中华皮肤科杂志
中華皮膚科雜誌
중화피부과잡지
Chinese Journal of Dermatology
2014年
10期
711-714
,共4页
王杨%孙树%王锦文%孙海峰%于兵%张雪莹
王楊%孫樹%王錦文%孫海峰%于兵%張雪瑩
왕양%손수%왕금문%손해봉%우병%장설형
痣%儿童%皮肤移植%真皮
痣%兒童%皮膚移植%真皮
지%인동%피부이식%진피
Nevus%Child%Skin transplantation%Dermis
目的 探讨自体头皮与脱细胞异体真皮复合移植方法修复儿童巨大色素痣的效果.方法 采用自体刃厚头皮与脱细胞异体真皮复合移植的方法修复儿童巨大色素痣,并以自体薄中厚皮片移植方法作对照,观察移植皮片成活率、创面愈合时间及瘢痕增生状况.结果 供皮区实验组创面愈合时间为(5.31±1.45)d,对照组为(11.63±1.69)d,两组比较差异有统计学意义(P＜0.05),实验组瘢痕评分为1.62±0.38,对照组为6.38±0.58,两组比较差异有统计学意义(P＜0.05);受皮区实验组皮肤移植成活率为(94.44±2.56)％,对照组为(95.13±3.13)％,移植皮片成活率于两组间差异无统计学意义,实验组瘢痕评分为5.38±0.62,对照组瘢痕评分为8.40±0.41,两组差异有统计学意义(P＜0.05).结论 自体头皮与脱细胞异体真皮复合移植修复儿童巨大色素痣,对供区损伤小,移植区形态及功能良好,值得应用.
目的 探討自體頭皮與脫細胞異體真皮複閤移植方法脩複兒童巨大色素痣的效果.方法 採用自體刃厚頭皮與脫細胞異體真皮複閤移植的方法脩複兒童巨大色素痣,併以自體薄中厚皮片移植方法作對照,觀察移植皮片成活率、創麵愈閤時間及瘢痕增生狀況.結果 供皮區實驗組創麵愈閤時間為(5.31±1.45)d,對照組為(11.63±1.69)d,兩組比較差異有統計學意義(P＜0.05),實驗組瘢痕評分為1.62±0.38,對照組為6.38±0.58,兩組比較差異有統計學意義(P＜0.05);受皮區實驗組皮膚移植成活率為(94.44±2.56)％,對照組為(95.13±3.13)％,移植皮片成活率于兩組間差異無統計學意義,實驗組瘢痕評分為5.38±0.62,對照組瘢痕評分為8.40±0.41,兩組差異有統計學意義(P＜0.05).結論 自體頭皮與脫細胞異體真皮複閤移植脩複兒童巨大色素痣,對供區損傷小,移植區形態及功能良好,值得應用.
목적 탐토자체두피여탈세포이체진피복합이식방법수복인동거대색소지적효과.방법 채용자체인후두피여탈세포이체진피복합이식적방법수복인동거대색소지,병이자체박중후피편이식방법작대조,관찰이식피편성활솔、창면유합시간급반흔증생상황.결과 공피구실험조창면유합시간위(5.31±1.45)d,대조조위(11.63±1.69)d,량조비교차이유통계학의의(P＜0.05),실험조반흔평분위1.62±0.38,대조조위6.38±0.58,량조비교차이유통계학의의(P＜0.05);수피구실험조피부이식성활솔위(94.44±2.56)％,대조조위(95.13±3.13)％,이식피편성활솔우량조간차이무통계학의의,실험조반흔평분위5.38±0.62,대조조반흔평분위8.40±0.41,량조차이유통계학의의(P＜0.05).결론 자체두피여탈세포이체진피복합이식수복인동거대색소지,대공구손상소,이식구형태급공능량호,치득응용.
Objective To evaluate the efficacy of composite skin grafts consisting of allogeneic acellular dermal matrix and autologous scalp in the repair of defects after excision of giant pigmented nevi in children.Methods Eighteen children with giant pigmented nevi were included in this study.All the patients received excision of giant pigmented nevi.The defects were repaired using composite skin grafts consisting of allogeneic acellular dermal matrix and autologous razor-thin scalp grafts in 10 children from June 2009 to October 2012 (test group),and using autologous thin or intermediate-thickness skin grafts in 8 children from March 2006 to May 2009 (control group).Donor site healing time,skin graft survival rate,and the degree of scar proliferation were compared between the two groups.Results Significant differences were observed at donor sites between the test group and control group in healing time ((5.31 ± 1.45) vs.(11.63 ± 1.69) days,P ＜ 0.05) and scar score (1.62 ± 0.38 vs.6.38 ± 0.58,P ＜ 0.05).At recipient sites,the survival rate of skin grafts was similar between the test group and control group ((94.44 ± 2.56)％ vs.(95.13 ± 3.13)％,P ＞ 0.05),while scar score was significantly different (5.38 ±0.62 vs.8.40 ± 0.41,P ＜ 0.05).Conclusion Composite skin grafts consisting of allogeneic acellular dermal matrix and autologous scalp appear to be a good option for the repair of defects after excision of giant pigmented nevi in children,with minor donor-site injuries and satisfying cosmetic and functional outcomes at recipient sites.
