CAJ | 학술논문

目的探讨肝转移灶切除在胃癌肝转移中的意义及不同的临床因素对其预后的影响.方法 2006-2012年32例胃癌合并肝转移患者行肝转移灶切除.16例患者同时进行胃癌根治术和肝转移灶切除术,其余16例先后完成胃癌根治术和肝转移灶切除术.通过临床及病理资料对患者的预后进行单因素及多元因素分析.结果 32例患者1、3及5年的生存率分别是84％,50％及37％,中位生存期为32个月,单因素分析显示,原发胃癌侵犯浆膜、血管瘤栓、淋巴结转移和手术中输血与不良预后相关,多因素分析显示,原发胃癌侵犯浆膜、血管瘤栓和肝转移灶直径＞5 cm者预后不良.结论胃癌合并肝转移患者肝转移灶直径＜5 cm,原发胃癌未侵犯浆膜层及血管无瘤栓者肝转移灶切除后能取得较好的预后.
목적 탐토간전이조절제재위암간전이중적의의급불동적림상인소대기예후적영향.방법 2006-2012년32례위암합병간전이환자행간전이조절제.16례환자동시진행위암근치술화간전이조절제술,기여16례선후완성위암근치술화간전이조절제술.통과림상급병리자료대환자적예후진행단인소급다원인소분석.결과 32례환자1、3급5년적생존솔분별시84％,50％급37％,중위생존기위32개월,단인소분석현시,원발위암침범장막、혈관류전、림파결전이화수술중수혈여불량예후상관,다인소분석현시,원발위암침범장막、혈관류전화간전이조직경＞5 cm자예후불량.결론 위암합병간전이환자간전이조직경＜5 cm,원발위암미침범장막층급혈관무류전자간전이조절제후능취득교호적예후.
Objective To evaluate hepatectomy for liver metastasis in patients of gastric carcinoma.Methods Clinical data of 32 gastric cancer cases undergoing hepatectomy for hepatic metastatic tumor were reviewed retrospectively from 2006 to 2012.16 cases underwent radical gastrectomy and synchronous hepatectomy for liver metastasis,the remaining 16 cases underwent radical resection of gastric cancer and liver resection heterochronously.The relationship between prognosis and clinicopathology was analyzed.Results The overall survival rates were 84％,50％ and 37％ in 1 year,3 years and 5 years.The median survival time was 32 months.Gastric cancer invasion depth,intravascular tumor thrombi,lymphatic metastasis and intraoperative blood transfusion was related to poor prognosis by single factor analysis,while gastric serosal invasion,tumor thrombus and liver metastasis tumor ＞ 5 cm related to poor prognosis by multiple factors analysis.Conclusions Gastric cancer patients with liver metastasis who underwent hepatic resection can achieve good prognosis if hepatic metastatic tumor ＜ 5cm or the primary gastric cancer does not invade the serosa and without tumor thrombus.