CAJ | 학술논문

目的探讨十二指肠神经内分泌肿瘤的诊断及治疗方法.方法回顾分析1999年8月至2012年7月收治的15例十二指肠神经内分泌肿瘤的临床病理资料.结果本组15例均经病理及免疫组化明确诊断.临床诊断主要为超声检查、胃镜检查、上消化道X线造影、腹部CT或核磁共振等,其中11例为胃镜检查发现,3例为超声检查发现,超声内镜穿刺病理诊断明确5例.15例中12例行腹部CT检查,1例行腹部MRI检查.本组行胰十二指肠切除术7例,十二指肠局部切除2例,内镜下病灶切除4例,全胃切除术1例,远端胃大部切除术1例.结论十二指肠神经内分泌肿瘤以内镜和影像诊断为主,外科手术是主要的治疗方式.对于G2期和G3期患者可选择胰十二指肠切除、十二指肠局部切除,对于G1期患者可选择内镜下病灶切除.
목적 탐토십이지장신경내분비종류적진단급치료방법.방법 회고분석1999년8월지2012년7월수치적15례십이지장신경내분비종류적림상병리자료.결과 본조15례균경병리급면역조화명학진단.림상진단주요위초성검사、위경검사、상소화도X선조영、복부CT혹핵자공진등,기중11례위위경검사발현,3례위초성검사발현,초성내경천자병리진단명학5례.15례중12례행복부CT검사,1례행복부MRI검사.본조행이십이지장절제술7례,십이지장국부절제2례,내경하병조절제4례,전위절제술1례,원단위대부절제술1례.결론 십이지장신경내분비종류이내경화영상진단위주,외과수술시주요적치료방식.대우G2기화G3기환자가선택이십이지장절제、십이지장국부절제,대우G1기환자가선택내경하병조절제.
Objective To evaluate the diagnosis and treatment of duodenal neuroendocrine tumors.Method We retrospectively analyzed data of 15 patients with duodenal neuroendocrine tumors admitted between August 1999 and July 2012.Result In all the 15 cases accurate and definitive diagnosis were achieved via pathological examination and immunohistochemistry.Clinical diagnostic methods included ultrasound,endoscopy,upper gastrointestinal imaging,abdominal CT,MRI,etc.7 cases underwent pancreaticoduodenectomy,2 cases were treated by local excision,4 cases by endoscopic excision,and total gastrectomy and distal gastrectomy was performed in one each case.Conclusions The diagnosis of duodenal neuroendocrine tumors is established mainly by endoscopy and diagnostic imaging.Surgical resection is the treatment of choice.Pancreatoduodenectomy and local excision is applicable for G2 and G3 patients while endoscopic excision can be used for G1 patients.