中华全科医师杂志
中華全科醫師雜誌
중화전과의사잡지
CHINESE JOURNAL OF GENERAL PRACTITIONERS
2013年
2期
104-107
,共4页
魏勇%刘少稳%周根青%欧阳平%费民忠
魏勇%劉少穩%週根青%歐暘平%費民忠
위용%류소은%주근청%구양평%비민충
血脂异常%心肌梗死%年龄分布
血脂異常%心肌梗死%年齡分佈
혈지이상%심기경사%년령분포
Dyslipidemia%Myocardial infarction%Age distribution
目的 探讨急性心肌梗死(AMI)患者血脂水平的增龄变化特点.方法 收集本院2007年5月至2011年7月符合入选标准的AMI患者1214例.依据年龄40 ～89岁间每10岁分为一组,比较各年龄组及不同性别间患者的血脂水平差异.结果 在7个年龄组中进行两两间TC或LDL-C水平比较,40 ～ 69岁各年龄组的TC水平[分别为(4.71±1.08)、(4.80±1.30)、(4.69±1.03) mmol/L]均高于70 ～89岁各年龄组[分别为(4.41±0.96)、(4.38±1.03) mmol/L],均P＜0.05(t值分别为2.381、2.323、4.382、3.965、3.317、3.096).59岁以下的3个年龄组间的TG水平差异无统计学意义,该3组的TG水平均高于60岁以上各年龄组；在50～89岁患者TG水平随年龄组的增加而逐渐降低.7个年龄组间的HDL-C水平两两比较,40 ～ 59岁各年龄组的HDL-C水平[分别为(1.03 ±0.23)、(1.05±0.26)mmol/L]均低于60 ～ 89岁各年龄组[分别为(1.11±0.28)、(1.11-±0.28)、(1.16±0.34) mmol/L],均P＜0.05(t值分别为-2.777、-2.789、-3.731、-2.543、-2.566、-3.644).AMI患者TC(r=-0.123,P＜0.01)、LDL-C(r=-0.139,P＜0.01)和TG(r=-0.287,P＜0.01)与年龄呈负相关,HDL-C与年龄呈正相关(r=0.125,P＜0.01).1214例AMI患者中,50～89岁各年龄组的女性TC水平高于同年龄组男性,50～69岁各年龄组的女性LDL-C水平高于同年龄组男性,40～79岁各年龄组的女性HDL-C水平高于同年龄组男性,均P＜0.05(t值分别为-2.878、-3.007、-3.352、-3.333).结论 总体上看,＜60岁的AMI患者的TC、LDL和TG高于≥60岁老年AMI患者,而HDL偏低.同年龄组女性TC、LDL、HDL水平有高于男性的趋势.
目的 探討急性心肌梗死(AMI)患者血脂水平的增齡變化特點.方法 收集本院2007年5月至2011年7月符閤入選標準的AMI患者1214例.依據年齡40 ～89歲間每10歲分為一組,比較各年齡組及不同性彆間患者的血脂水平差異.結果 在7箇年齡組中進行兩兩間TC或LDL-C水平比較,40 ～ 69歲各年齡組的TC水平[分彆為(4.71±1.08)、(4.80±1.30)、(4.69±1.03) mmol/L]均高于70 ～89歲各年齡組[分彆為(4.41±0.96)、(4.38±1.03) mmol/L],均P＜0.05(t值分彆為2.381、2.323、4.382、3.965、3.317、3.096).59歲以下的3箇年齡組間的TG水平差異無統計學意義,該3組的TG水平均高于60歲以上各年齡組；在50～89歲患者TG水平隨年齡組的增加而逐漸降低.7箇年齡組間的HDL-C水平兩兩比較,40 ～ 59歲各年齡組的HDL-C水平[分彆為(1.03 ±0.23)、(1.05±0.26)mmol/L]均低于60 ～ 89歲各年齡組[分彆為(1.11±0.28)、(1.11-±0.28)、(1.16±0.34) mmol/L],均P＜0.05(t值分彆為-2.777、-2.789、-3.731、-2.543、-2.566、-3.644).AMI患者TC(r=-0.123,P＜0.01)、LDL-C(r=-0.139,P＜0.01)和TG(r=-0.287,P＜0.01)與年齡呈負相關,HDL-C與年齡呈正相關(r=0.125,P＜0.01).1214例AMI患者中,50～89歲各年齡組的女性TC水平高于同年齡組男性,50～69歲各年齡組的女性LDL-C水平高于同年齡組男性,40～79歲各年齡組的女性HDL-C水平高于同年齡組男性,均P＜0.05(t值分彆為-2.878、-3.007、-3.352、-3.333).結論 總體上看,＜60歲的AMI患者的TC、LDL和TG高于≥60歲老年AMI患者,而HDL偏低.同年齡組女性TC、LDL、HDL水平有高于男性的趨勢.
목적 탐토급성심기경사(AMI)환자혈지수평적증령변화특점.방법 수집본원2007년5월지2011년7월부합입선표준적AMI환자1214례.의거년령40 ～89세간매10세분위일조,비교각년령조급불동성별간환자적혈지수평차이.결과 재7개년령조중진행량량간TC혹LDL-C수평비교,40 ～ 69세각년령조적TC수평[분별위(4.71±1.08)、(4.80±1.30)、(4.69±1.03) mmol/L]균고우70 ～89세각년령조[분별위(4.41±0.96)、(4.38±1.03) mmol/L],균P＜0.05(t치분별위2.381、2.323、4.382、3.965、3.317、3.096).59세이하적3개년령조간적TG수평차이무통계학의의,해3조적TG수평균고우60세이상각년령조；재50～89세환자TG수평수년령조적증가이축점강저.7개년령조간적HDL-C수평량량비교,40 ～ 59세각년령조적HDL-C수평[분별위(1.03 ±0.23)、(1.05±0.26)mmol/L]균저우60 ～ 89세각년령조[분별위(1.11±0.28)、(1.11-±0.28)、(1.16±0.34) mmol/L],균P＜0.05(t치분별위-2.777、-2.789、-3.731、-2.543、-2.566、-3.644).AMI환자TC(r=-0.123,P＜0.01)、LDL-C(r=-0.139,P＜0.01)화TG(r=-0.287,P＜0.01)여년령정부상관,HDL-C여년령정정상관(r=0.125,P＜0.01).1214례AMI환자중,50～89세각년령조적녀성TC수평고우동년령조남성,50～69세각년령조적녀성LDL-C수평고우동년령조남성,40～79세각년령조적녀성HDL-C수평고우동년령조남성,균P＜0.05(t치분별위-2.878、-3.007、-3.352、-3.333).결론 총체상간,＜60세적AMI환자적TC、LDL화TG고우≥60세노년AMI환자,이HDL편저.동년령조녀성TC、LDL、HDL수평유고우남성적추세.
Objective To investigate the variation of lipid profile in patients with acute myocardial infarction (AMI) of different age groups.Methods Total 1214 patients of AMI were admitted to our hospital from May 2007 to July 2011.The age of patients ranged 40-89 years,and patients were divided into 5 age groups with 10-years step.Differences in lipid levels were observed by using pair-wise comparison among different age groups.Results Pair-wise comparisons among different age groups indicated that TC levels were higher in 40-69 years age groups [(4.71 ± 1.08),(4.80 ± 1.30),(4.69 ± 1.03) mmol/L,respectively] than those in the 70-89 age groups [(4.41 ± 0.96),(4.38 ± 1.03) mmol/L],all P ＜ 0.05(t values were 2.381,2.323,4.382,3.965,3.317,3.096).TG levels among three age groups ＜ 59 years had no significant difference,which were higher than those in groups over 60 years.Among 50-89 years age groups,TG gradually reduced with increase of age.HDL levels were lower in 40-59 years age groups [(1.03 ± 0.23),(1.05 ± 0.26) mmol/L,respectively] than those in 60-89 years age groups [(1.11 ±0.28),(1.11±0.28),(1.16±0.34) mmol/L,respectively],allP＜0.05 (t values were-2.777,-2.789,-3.731,-2.543,-2.566,-3.644).Total cholesterol (TC) (r =-0.123,P ＜0.01),lowdensity lipoprotein cholesterol (LDL) (r =-0.139,P ＜ 0.01) and triglyceride (TG) (r =-0.287,P ＜0.01) were negatively but high-density lipoprotein cholesterol (HDL) (r =0.125,P ＜ 0.01) was positively correlated with age of patients.TC levels in female patients were higher than those in male patients in 50-89 years age groups; LDL levels in female patients were higher than those in male patients in 50-69 years age groups and HDL levels in female patients were higher than those in male patients in 40-79 years age groups (all P ＜ 0.05,t values were-2.878,-3.007,-3.352,-3.333).Conclusions Results show that the non-elderly AMI patients (＜60 years) have higher levels of TC,LDL and TG,and lower level of HDL than the elderly patients; the TC,LDL and HDL levels are higher in female AMI patients than those in male patients at the same age groups.
