CAJ | 학술논문

回顾性分析3例合并肺部病变的Good综合征患者临床资料,并结合文献复习总结该病临床表现、肺部病变特征及诊断治疗.3例患者无显著的低γ球蛋白血症,但外周血淋巴细胞亚群检测均可见不同程度异常.胸腺瘤患者出现反复呼吸道感染时应考虑Good综合征的可能,Good综合征可出现弥漫性泛细支气管炎样肺部表现,也可表现为间质性肺病,早期进行免疫状况筛查、积极纠正原发免疫缺陷对改善预后有益.
회고성분석3례합병폐부병변적Good종합정환자림상자료,병결합문헌복습총결해병림상표현、폐부병변특정급진단치료.3례환자무현저적저γ구단백혈증,단외주혈림파세포아군검측균가견불동정도이상.흉선류환자출현반복호흡도감염시응고필Good종합정적가능,Good종합정가출현미만성범세지기관염양폐부표현,야가표현위간질성폐병,조기진행면역상황사사、적겁규정원발면역결함대개선예후유익.
Three cases of Good's syndrome with pulmonary lesions in our hospital from June 1,2010 to June 1,2013 were retrospective analyzed and relevant literatures were reviewed.Clinical manifestation,characteristics of pulmonary lesions,diagnosis and treatment were summarized.Abnormality of lymphocyte subpopulation to varying degrees in peripheral blood was detected in all 3 cases.However none showed hypogammaglobulinemia.If thymoma patients developed recurrent respiratory infections,Good's syndrome should be considered.Pulmonary manifestations of Good's syndrome have lesions similar to those of diffuse panbronchiolitis or interstitial lung disease.Early screening of immune competency and treatment for immunodeficiency may improve prognosis.