CAJ | 학술논문

对上海市徐汇区6 008例60岁以上体检的老年人进行抗M2型线粒体抗体(胶体金免疫层析法)筛查,并以酶联免疫吸附法复测,其阳性率为1.31％ (79/6 008),其中男性0.82％(18/2 186),女性1.60％ (61/3 822).经进一步检查显示11例抗M2型线粒体抗体阳性者中,8例确诊为原发性胆汁性肝硬化,3例高度疑诊;11例患者肝功能生化指标和/或临床症状等均有不同程度的异常.
대상해시서회구6 008례60세이상체검적노년인진행항M2형선립체항체(효체금면역층석법)사사,병이매련면역흡부법복측,기양성솔위1.31％ (79/6 008),기중남성0.82％(18/2 186),녀성1.60％ (61/3 822).경진일보검사현시11례항M2형선립체항체양성자중,8례학진위원발성담즙성간경화,3례고도의진;11례환자간공능생화지표화/혹림상증상등균유불동정도적이상.
Serum anti-M2 mitochondrial antibody (AMA-M2) was screened with immune colloidal gold technique in 6 008 individuals aged over 60 years who underwent health check-up in Xuhui District of Shanghai,the positive samples were retested with ELISA method.The results showed that 1.31％ (79/6 008) individuals were AMA-M2 positive; the positive rate was 0.82％ (18/2 186) in males and 1.60％ (61/3 822) in females.Eleven subjects with positive AMA-M2 underwent further investigation,8 cases were diagnosed as primary biliary cirrhosis (PBC) and the remaining 3 were highly suspected as PBC.All 11 individuals were abnormal in biochemical tests of liver function and/or clinical symptoms.