CAJ | 학술논문

回顾性分析1990年至今住院患者严重过敏反应的发生率,42例严重过敏反应患者的一般情况、临床表现、病因,2005年前后严重过敏反应发生率、患者性别年龄差异、临床表现和病因的变化.患者平均年龄(39±16)岁,男∶女=1.0∶2.2,2005年后严重过敏反应的例数较前明显增加(30例与12例);2005年后发生严重过敏反应的女性明显多于2005年前(24例与5例);2005年后出现神经系统、循环系统症状及血压下降的比例明显低于2005年前(P＜0.01、＜0.05、＜0.01);2005年后手术中发生严重过敏反应的构成比较2005年前明显增加(43.3％与1/12);引起严重过敏反应的最主要病因为药物(35/42),药物中最常见的是抗生素(14/35).
회고성분석1990년지금주원환자엄중과민반응적발생솔,42례엄중과민반응환자적일반정황、림상표현、병인,2005년전후엄중과민반응발생솔、환자성별년령차이、림상표현화병인적변화.환자평균년령(39±16)세,남∶녀=1.0∶2.2,2005년후엄중과민반응적례수교전명현증가(30례여12례);2005년후발생엄중과민반응적녀성명현다우2005년전(24례여5례);2005년후출현신경계통、순배계통증상급혈압하강적비례명현저우2005년전(P＜0.01、＜0.05、＜0.01);2005년후수술중발생엄중과민반응적구성비교2005년전명현증가(43.3％여1/12);인기엄중과민반응적최주요병인위약물(35/42),약물중최상견적시항생소(14/35).
To analyze the incidence,clinical manifestations and causes of 42 in patients with anaphylaxis from 1990 and follow its change before and after 2005 retrospectively.The mean age was (39 ± 16) years.The ratio of male and female was 1:2.2.The incidence increased obviously after 2005 (30 vs.12).A majority of patients were females after 2005 (24 vs.5).The proportions of patients with impaired nerve system,circulatory system and hypotension decreased after 2005 (P ＜ 0.01,P ＜ 0.05,P ＜ 0.01).Anaphylaxis attacked more often intra-operatively after 2005 (43.3 ％ vs.1 / 12).The most common cause was drug(35/42),especially antibiotics(14/35).