CAJ | 학술논문

目的了解男性在职干部中超重、肥胖及多种代谢疾病的发病情况.方法对2012年在我院行年度体检的1 018例男性在职干部,测量血压、腰围、身高、体重,检测空腹血糖(FPG)、TC、TG、尿酸水平,并根据BMI分为消瘦组(BMI＜ 18.5 kg/m2,20例)、正常组(18.5 kg/m2≤BMI＜ 24kg/m2,502例)、超重组(24 kg/m2≤BMI＜ 28 kg/m2,416例)和肥胖组(BMI≥28 kg/m2,80例)4个组,进行组间比较.结果 ①男性在职干部的超重及肥胖情况分布:超重40.9％ (416/1 018),肥胖7.8％ (80/1 018),向心性肥胖53.0％ (540/1 018),代谢综合征(MS) 11.2％ (114/1 018).②从消瘦、正常、超重至肥胖组,FPG、TC、TG、尿酸、收缩压、舒张压水平逐步增高,FPG分别为(4.78±0.36)mmol/L ～(5.30±1.65) mmol/L,TC分别为(4.93 ±0.71) mmol/L ～(5.33 ±0.97) mmol/L,TG为(1.12±0.45) mmol/L～(2.23±1.07) mmol/L,尿酸分别为(356 ± 25)和(354±45) μmol/L～(373±58) μmol/L,收缩压分别为(108.7±10.9)mmHg～(127.2±12.0) mmHg(1 mmHg =0.133 kPa),舒张压分别为(69.9±7.1)mmHg ～(82.6±9.5)mmHg,各组间比较差异均有统计学意义(F值分别为4.82、12.09、40.55、6.19、28.97和49.29,均P＜0.01);随着BMI增大,高血压(0％、11.8％、27.4％、37.5％)、糖尿病(0、1.6％、5.5％、10.0％)、血脂异常(40.0％、47.2％、66.3％、71.2％)、高尿酸血症(0、5.0％、13.5％、13.8％)的患病率越高(x2值分别为55.97、9.65、43.32和24.08,均P＜0.01),同时患上述多种代谢疾病的比例也越高,患3种以上代谢性疾病的比例分别为0 (0/20)、1.4％(7/502)、5.8％ (24/416)、13.8％ (11/80) (x2 =31.90,P＜0.01).结论肥胖与各种代谢异常疾病密切相关,是心血管病的高风险因素.
목적 료해남성재직간부중초중、비반급다충대사질병적발병정황.방법 대2012년재아원행년도체검적1 018례남성재직간부,측량혈압、요위、신고、체중,검측공복혈당(FPG)、TC、TG、뇨산수평,병근거BMI분위소수조(BMI＜ 18.5 kg/m2,20례)、정상조(18.5 kg/m2≤BMI＜ 24kg/m2,502례)、초중조(24 kg/m2≤BMI＜ 28 kg/m2,416례)화비반조(BMI≥28 kg/m2,80례)4개조,진행조간비교.결과 ①남성재직간부적초중급비반정황분포:초중40.9％ (416/1 018),비반7.8％ (80/1 018),향심성비반53.0％ (540/1 018),대사종합정(MS) 11.2％ (114/1 018).②종소수、정상、초중지비반조,FPG、TC、TG、뇨산、수축압、서장압수평축보증고,FPG분별위(4.78±0.36)mmol/L ～(5.30±1.65) mmol/L,TC분별위(4.93 ±0.71) mmol/L ～(5.33 ±0.97) mmol/L,TG위(1.12±0.45) mmol/L～(2.23±1.07) mmol/L,뇨산분별위(356 ± 25)화(354±45) μmol/L～(373±58) μmol/L,수축압분별위(108.7±10.9)mmHg～(127.2±12.0) mmHg(1 mmHg =0.133 kPa),서장압분별위(69.9±7.1)mmHg ～(82.6±9.5)mmHg,각조간비교차이균유통계학의의(F치분별위4.82、12.09、40.55、6.19、28.97화49.29,균P＜0.01);수착BMI증대,고혈압(0％、11.8％、27.4％、37.5％)、당뇨병(0、1.6％、5.5％、10.0％)、혈지이상(40.0％、47.2％、66.3％、71.2％)、고뇨산혈증(0、5.0％、13.5％、13.8％)적환병솔월고(x2치분별위55.97、9.65、43.32화24.08,균P＜0.01),동시환상술다충대사질병적비례야월고,환3충이상대사성질병적비례분별위0 (0/20)、1.4％(7/502)、5.8％ (24/416)、13.8％ (11/80) (x2 =31.90,P＜0.01).결론 비반여각충대사이상질병밀절상관,시심혈관병적고풍험인소.
Objective To investigate the prevalence of overweight,obesity and related metabolic diseases among male public institution office workers in health check-up.Methods Total 1 018 male public institution office workers aged 23-60 underwent annual health check-up at our hospital in 2012.The data including blood pressure,waist circumference,height,body weight,serum glucose,plasma lipids and serum uric acid were analyzed.According to body mass index (BMI),the subjects were classified as:underweight(BMI ＜ 18.5 kg/m2),normal weight (18.5 kg/m2 ≤ BMI ＜ 24 kg/m2),overweight (24 kg/m2 ≤ BMI ＜ 28 kg/m2) and obesity(BMI≥28 kg/m2).Results The prevalence of overweight,obesity,central obesity and metabolic syndrome (MS) were 40.9％ (416/1 018),7.9％ (80/1 018),53.0％ (540/1 018),and 11.2％ (114/1 018),respectively.There were significant differences in fasting blood glucose (FPG),TC,TG,uric acid(UA),systolic blood pressure(SBP) and diastolic blood pressure(DBP) levels among different groups (F =4.82,12.09,40.55,6.19,28.97 and 49.29,respectively,all P ＜0.01).The prevalence rate of hypertension in underweight,normal,overweight and obesity groups was 0,11.8％,27.4％ and 37.5％,respectively; that of diabetes was 0,1.6％,5.5％ and 10.0％,respectively; that of hyperlipidemia was 40.0％,47.2％,66.3％ and 71.2％,respectively; that of hyperuricemia was 0,5.0％,13.5％ and 13.8％,respectively,which showed that with the increasing of BMI,the prevalence rates of related metabolic diseases were increased(x2 =55.97,9.65,43.32 and 24.08,all P ＜0.01).And the co-morbidity rate with ≥3 diseases in 4 BMI groups were 0(0/20),1.4％ (7/502),5.8％ (24/416) and 13.8％ (11/80),respectively (x2 =31.90,P ＜ 0.01).Conclusion Obesity and overweight are correlated with metabolic disorders and the obese subjects are at high risk for cardiovascular diseases.