CAJ | 학술논문

目的探讨成人松果体实质肿瘤的手术疗效.方法回顾性分析北京天坛医院神经外科2007年1月至2013年10月收治了39例成人(≥18岁)松果体实质细胞肿瘤的临床资料并进行随访.结果肿瘤全切除19例,次全切除12例,部分切除6例,仅行肿瘤活检2例,无手术死亡病例.术后病理结果:松果体细胞瘤14例,中分化松果体实质肿瘤15例,松果体母细胞瘤10例.随访到的32例患者中,5例患者因肿瘤复发而死亡,中分化和松果体母细胞瘤中位生存期分别为34.5个月和29.8个月.结论松果体细胞瘤手术治疗效果良好,中分化松果体实质肿瘤和松果体母细胞瘤治疗应首选手术,放化疗的效果尚待确定.
목적 탐토성인송과체실질종류적수술료효.방법 회고성분석북경천단의원신경외과2007년1월지2013년10월수치료39례성인(≥18세)송과체실질세포종류적림상자료병진행수방.결과 종류전절제19례,차전절제12례,부분절제6례,부행종류활검2례,무수술사망병례.술후병리결과:송과체세포류14례,중분화송과체실질종류15례,송과체모세포류10례.수방도적32례환자중,5례환자인종류복발이사망,중분화화송과체모세포류중위생존기분별위34.5개월화29.8개월.결론 송과체세포류수술치료효과량호,중분화송과체실질종류화송과체모세포류치료응수선수술,방화료적효과상대학정.
Objective To study the clinical characteristics,surgical treatment and outcome of pineal parenchymal tumors(PPT) in adult patients.Methods The adult patients (≥18 years old) with PPT diagnosed between 2007 and 2013 were retrospectively studied and their surgical results were followed-up.Results 37 PPT tumors were surgically removed,including 19 total removal,12 subtotal removal and 6 partial removal.The biopsy was made in 2 patients.The pathological type of 14 cases was pineocytoma,15 pineal parenchymal tumors of intermediate differentiation,and 10 pinealoblastoma.In 32 patients of follow-up,there were 5 patients died because of tumor recurrence.The median overall survival was 34.5 months for intermediate differentiation and 29.8 months for pinealoblastoma.Conclusions Pineocytomas' patients have good survival prognosis after surgical treatment.Microsurgery is the most effective therapy for pineal parenchymal tumor of intermediate differentiation and pineoblastoma.The role of adjuvant radiotherapy and chemotherapy remains to be defined.