中华神经外科杂志
中華神經外科雜誌
중화신경외과잡지
Chinese Journal of Neurosurgery
2014年
10期
1005-1007
,共3页
垂体腺瘤%脑脊液漏%外科治疗%临床特征
垂體腺瘤%腦脊液漏%外科治療%臨床特徵
수체선류%뇌척액루%외과치료%림상특정
Pituitary adenoma%Cerebral spinal fluid rhinorrhea%Surgical treatment%Clinical features
目的 探讨垂体腺瘤合并脑脊液鼻漏的临床特点及外科治疗方法.方法 选取近2010年2月到2013年12月的合并脑脊液鼻漏的垂体腺瘤患者18例,研究其临床特点,均一期切除肿瘤同时修补脑脊液鼻漏,修补鼻漏的方式方法根据不同患者的具体情况确定.结果 在所有18例患者中,12例肿瘤获得全切除,6例近全切除,所有患者鼻漏修补成功,其中1例二次手术修补成功,病理结果分析,其中催乳素腺瘤8例,生长激素腺瘤3例,无功能腺瘤7例.随访结果,所有患者术后均动态观察头部MRI扫描,部分患者服药或以立体定向放疗控制肿瘤.结论 垂体腺瘤合并脑脊液鼻漏是一种少见的临床疾病,一旦确诊就需外科治疗,应切除肿瘤同时修补脑脊液鼻漏,根据具体情况选择合适的修补方式至关重要.
目的 探討垂體腺瘤閤併腦脊液鼻漏的臨床特點及外科治療方法.方法 選取近2010年2月到2013年12月的閤併腦脊液鼻漏的垂體腺瘤患者18例,研究其臨床特點,均一期切除腫瘤同時脩補腦脊液鼻漏,脩補鼻漏的方式方法根據不同患者的具體情況確定.結果 在所有18例患者中,12例腫瘤穫得全切除,6例近全切除,所有患者鼻漏脩補成功,其中1例二次手術脩補成功,病理結果分析,其中催乳素腺瘤8例,生長激素腺瘤3例,無功能腺瘤7例.隨訪結果,所有患者術後均動態觀察頭部MRI掃描,部分患者服藥或以立體定嚮放療控製腫瘤.結論 垂體腺瘤閤併腦脊液鼻漏是一種少見的臨床疾病,一旦確診就需外科治療,應切除腫瘤同時脩補腦脊液鼻漏,根據具體情況選擇閤適的脩補方式至關重要.
목적 탐토수체선류합병뇌척액비루적림상특점급외과치료방법.방법 선취근2010년2월도2013년12월적합병뇌척액비루적수체선류환자18례,연구기림상특점,균일기절제종류동시수보뇌척액비루,수보비루적방식방법근거불동환자적구체정황학정.결과 재소유18례환자중,12례종류획득전절제,6례근전절제,소유환자비루수보성공,기중1례이차수술수보성공,병리결과분석,기중최유소선류8례,생장격소선류3례,무공능선류7례.수방결과,소유환자술후균동태관찰두부MRI소묘,부분환자복약혹이입체정향방료공제종류.결론 수체선류합병뇌척액비루시일충소견적림상질병,일단학진취수외과치료,응절제종류동시수보뇌척액비루,근거구체정황선택합괄적수보방식지관중요.
Objective To investigate the clinical features and surgical treatment of pituitary adenoma with cerebral spinal fluid (CSF) rhinorrhea.Methods The clinical characteristics,uniformity of removal of the tumor and repair techniques of the CSF rhinorrhea of 18 cases of pituitary adenoma patients combined with CSF rhinorrhea in nearly four years were studied and the patterns of repair ways for CSF rhinorrhea to the specific circumstances of different patients were determined.Results In all 18 patients,total tumor resection were obtained in 12 cases and subtotal resection in 6 cases.All patients' rhinorrhea repair was successful,including one case of secondary surgical repair.Pathology analysis:prolactinomas in 8 cases,GH in 3,and non-functioning in 7.11 patients were dynamically observed postoperatively through MRI scans.Some patients underwent medication or stereotactic radiotherapy to control the residual tumors.Conclusions CSF rhinorrhea in pituitary adenoma patients was rare.Once it was diagnosed in pituitary adenoma patient,surgical treatment was necessary.The tumor should be removed and the reconstruction of the skull base defect should be performed.It was essential to choose the right way to repair CSF leakage depending on the specific circumstances.
