中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2013年
3期
305-307
,共3页
利晞%梁舜尧%谭理连%胡滨%侯仲军%陈耀棠%于晓君%曹兵艺
利晞%樑舜堯%譚理連%鬍濱%侯仲軍%陳耀棠%于曉君%曹兵藝
리희%량순요%담리련%호빈%후중군%진요당%우효군%조병예
脑动静脉畸形%脑水肿%立体定向放射治疗%伽玛刀%并发症
腦動靜脈畸形%腦水腫%立體定嚮放射治療%伽瑪刀%併髮癥
뇌동정맥기형%뇌수종%입체정향방사치료%가마도%병발증
Brain arteriovenous malformation%Cerebral edema%Stereotactic radiosurgery%Gamma knife%Complication
目的 探讨脑动静脉畸形γ刀放射治疗后不同随访阶段放射性脑水肿的发生率.方法 回顾性分析广州医学院第二附属医院放射科自1995年1月至2010年12月十余年间内经γ刀治疗的脑动静脉畸形患者的临床资料,共经磁共振检查随访351例次.统计γ刀术后不同随访阶段放射性脑水肿发生率并采用采用x2检验分析. 结果 γ刀放射治疗后本组患者放射性脑水肿阳性率为36.2％；不同随访阶段放射性脑水肿阳性率分别为:≤12月43.0％,13～36月45.3％,37～60月23.1％,61～120月13.6％,＞120月5.9％；各随访阶段间放射性脑水肿的发生率比较差异有统计学意义(x2=26.514,P=0.000). 结论 放射性脑水肿是脑动静脉畸形γ刀治疗后最常见的并发症之一,部分患者可出现顽固性放射性脑水肿.γ刀治疗后第一阶段(≤12月)、第二阶段(13～36月)放射性脑水肿发生率较高,应临床密切关注.
目的 探討腦動靜脈畸形γ刀放射治療後不同隨訪階段放射性腦水腫的髮生率.方法 迴顧性分析廣州醫學院第二附屬醫院放射科自1995年1月至2010年12月十餘年間內經γ刀治療的腦動靜脈畸形患者的臨床資料,共經磁共振檢查隨訪351例次.統計γ刀術後不同隨訪階段放射性腦水腫髮生率併採用採用x2檢驗分析. 結果 γ刀放射治療後本組患者放射性腦水腫暘性率為36.2％；不同隨訪階段放射性腦水腫暘性率分彆為:≤12月43.0％,13～36月45.3％,37～60月23.1％,61～120月13.6％,＞120月5.9％；各隨訪階段間放射性腦水腫的髮生率比較差異有統計學意義(x2=26.514,P=0.000). 結論 放射性腦水腫是腦動靜脈畸形γ刀治療後最常見的併髮癥之一,部分患者可齣現頑固性放射性腦水腫.γ刀治療後第一階段(≤12月)、第二階段(13～36月)放射性腦水腫髮生率較高,應臨床密切關註.
목적 탐토뇌동정맥기형γ도방사치료후불동수방계단방사성뇌수종적발생솔.방법 회고성분석엄주의학원제이부속의원방사과자1995년1월지2010년12월십여년간내경γ도치료적뇌동정맥기형환자적림상자료,공경자공진검사수방351례차.통계γ도술후불동수방계단방사성뇌수종발생솔병채용채용x2검험분석. 결과 γ도방사치료후본조환자방사성뇌수종양성솔위36.2％；불동수방계단방사성뇌수종양성솔분별위:≤12월43.0％,13～36월45.3％,37～60월23.1％,61～120월13.6％,＞120월5.9％；각수방계단간방사성뇌수종적발생솔비교차이유통계학의의(x2=26.514,P=0.000). 결론 방사성뇌수종시뇌동정맥기형γ도치료후최상견적병발증지일,부분환자가출현완고성방사성뇌수종.γ도치료후제일계단(≤12월)、제이계단(13～36월)방사성뇌수종발생솔교고,응림상밀절관주.
Objective To study the incidence of cerebral edema in patients with cerebral arteriovenous malformations (AVMs) treated by Gamma knife.Methods The clinical data of 351 patients with AVMs,admitted to and treated with gamma knife in our hospital from January 1995 to December 2010,were retrospectively analyzed.MR imaging was performed on these patients to review the characteristics of cerebral edema and compare the different incidences of cerebral edema at different follow up periods; chi-square analysis was employed on these data.Results After being treated with gamma knife,the total positive rate of cerebral edema was 36.2％.At different follow-up periods,the positive rates of cerebral edema were different:43.0％ within 12 months of treatment,45.3％ at 13-36 months after treatment,23.1％ at 37-60 months after treatment,13.6％ at 61-120 months after treatment,and 5.9％ more than 120 months after treatment; significant difference was noted between each two follow up periods (x2=26.514,P=0.000).Conclusion Edema is one of the common complications after gamma knife treatment; stubborn cerebral edema might appear in some; the tiptop of cerebral edema incidence rate is at 0 to 36 months after treatment,which needs to be paid attention in clinic.
