CAJ | 학술논문

目的回顾性分析评价伽玛刀对海绵窦海绵状血管瘤的治疗作用. 方法海军总医院全军神经外科研究所自1997年11月至2011年6月应用伽玛刀治疗海绵窦海绵状血管瘤33例,其中10例为术后残留,23例经影像诊断.肿瘤平均直径29 mm(12～65 mm).伽玛刀治疗的平均周边剂量12.5Gy(9～16Gy),平均等剂量曲线47.7％(40％～50％). 结果 32例患者获随访,平均随访时间46个月(6～135个月).30例(93.8％)治疗后症状明显好转或消失,2例(6.2％)同治疗前.本组治疗后无其他颅神经功能受损症状出现；肿瘤基本消失9例(28.1％),肿瘤体积明显萎缩21例(65.6％),体积较伽玛刀治疗前无明显改变2例(6.7％),肿瘤总控制率100％.2例患者因治疗前肿瘤体积巨大行分次伽玛刀治疗. 结论伽玛刀治疗海绵窦海绵状血管瘤安全有效,并可有效改善其临床症状.
목적 회고성분석평개가마도대해면두해면상혈관류적치료작용. 방법 해군총의원전군신경외과연구소자1997년11월지2011년6월응용가마도치료해면두해면상혈관류33례,기중10례위술후잔류,23례경영상진단.종류평균직경29 mm(12～65 mm).가마도치료적평균주변제량12.5Gy(9～16Gy),평균등제량곡선47.7％(40％～50％). 결과 32례환자획수방,평균수방시간46개월(6～135개월).30례(93.8％)치료후증상명현호전혹소실,2례(6.2％)동치료전.본조치료후무기타로신경공능수손증상출현；종류기본소실9례(28.1％),종류체적명현위축21례(65.6％),체적교가마도치료전무명현개변2례(6.7％),종류총공제솔100％.2례환자인치료전종류체적거대행분차가마도치료. 결론 가마도치료해면두해면상혈관류안전유효,병가유효개선기림상증상.
Objective To evaluate the role of Gamma knife surgery (GKS) in the treatment of cavemous sinus hemangiomas.Methods Thirty-three patients underwent GKS for cavernous sinus hemangioma at our hospital from November 1997 to June 2011 were chosen in our study; 10 had prior tumor resection and 23 underwent radiosurgery on the basis of imaging diagnosis only.The mean diameter of 33 tumors was 29 mm.(ranged 12-65 mm).The mean marginal dose was 12.5 Gy (ranged 9-16 Gy),and the mean prescription isodose configuration was 47.7％ (ranged 40％-50％).Results Follow up in the 32 patients was performed for 6-135 months (mean 46 months).Neurological symptoms or signs improved or dismissed in 30 patients (93.8 ％) and a stable lesion was noted in 2 patients (6.2％).No other cranial nerve dysfunction symptoms appeared.On imaging,the hemangiomas almost disappeared in 9 patients (28.1％),shrank in 21 (65.6％) and remained stable in 2 patients (6.7％).Tumor growth control was achieved in all patients (100％).Two patients because of the big tumor volume received fractionated gamma knife treatment.Conclusion The use of GKS in treating cavernous sinus hemangiomas is safe and effective,and can achieve functional improvement.