中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2013年
9期
944-946
,共3页
刘克君%荆国杰%姚晓腾%景英朝%李毅毅%李王安%谢乙团%赵冬青%李百升
劉剋君%荊國傑%姚曉騰%景英朝%李毅毅%李王安%謝乙糰%趙鼕青%李百升
류극군%형국걸%요효등%경영조%리의의%리왕안%사을단%조동청%리백승
弥漫性轴索损伤%弥散张量成像%敏感性%各向异性分数%格拉斯哥昏迷评分
瀰漫性軸索損傷%瀰散張量成像%敏感性%各嚮異性分數%格拉斯哥昏迷評分
미만성축색손상%미산장량성상%민감성%각향이성분수%격랍사가혼미평분
Diffuse axon damage%Diffusion tensor imaging%Sensitivity%Fractional anisotropy%Glasgow coma scale
目的 研究弥散张量成像(DTI)诊断弥漫性轴索损伤(DAI)的敏感性,及探讨中脑区各向异性分数(FA)值与GCS评分的相关性以定量评估DAI的损伤程度. 方法 选择惠州市第一人民医院及惠州市中心人民医院神经外科自2007年1月至2013年1月临床诊断为DAI的105例患者为研究对象,对其在入院时行CT、MRI平扫及DTI扫描,观察比较3种不同影像学方法检测DAI损伤病灶的敏感性差异,并分析其中36例DAI患者中脑区FA值与入院时GCS评分的相关性. 结果 CT检测DAI损伤病灶的敏感性为70.48％,MRI平扫为82.86％,DTI为95.24％,3者比较差异具有统计学意义(P＜0.05),其中以DTI检查诊断的敏感性为最高.患者入院时GCS评分与中脑区FA值存在正相关关系(r=0.977,P=0.000). 结论 DTI不仅在诊断DAI敏感性方面优于CT和MRI平扫,且在一定程度上可客观地评估DAI的损伤程度.
目的 研究瀰散張量成像(DTI)診斷瀰漫性軸索損傷(DAI)的敏感性,及探討中腦區各嚮異性分數(FA)值與GCS評分的相關性以定量評估DAI的損傷程度. 方法 選擇惠州市第一人民醫院及惠州市中心人民醫院神經外科自2007年1月至2013年1月臨床診斷為DAI的105例患者為研究對象,對其在入院時行CT、MRI平掃及DTI掃描,觀察比較3種不同影像學方法檢測DAI損傷病竈的敏感性差異,併分析其中36例DAI患者中腦區FA值與入院時GCS評分的相關性. 結果 CT檢測DAI損傷病竈的敏感性為70.48％,MRI平掃為82.86％,DTI為95.24％,3者比較差異具有統計學意義(P＜0.05),其中以DTI檢查診斷的敏感性為最高.患者入院時GCS評分與中腦區FA值存在正相關關繫(r=0.977,P=0.000). 結論 DTI不僅在診斷DAI敏感性方麵優于CT和MRI平掃,且在一定程度上可客觀地評估DAI的損傷程度.
목적 연구미산장량성상(DTI)진단미만성축색손상(DAI)적민감성,급탐토중뇌구각향이성분수(FA)치여GCS평분적상관성이정량평고DAI적손상정도. 방법 선택혜주시제일인민의원급혜주시중심인민의원신경외과자2007년1월지2013년1월림상진단위DAI적105례환자위연구대상,대기재입원시행CT、MRI평소급DTI소묘,관찰비교3충불동영상학방법검측DAI손상병조적민감성차이,병분석기중36례DAI환자중뇌구FA치여입원시GCS평분적상관성. 결과 CT검측DAI손상병조적민감성위70.48％,MRI평소위82.86％,DTI위95.24％,3자비교차이구유통계학의의(P＜0.05),기중이DTI검사진단적민감성위최고.환자입원시GCS평분여중뇌구FA치존재정상관관계(r=0.977,P=0.000). 결론 DTI불부재진단DAI민감성방면우우CT화MRI평소,차재일정정도상가객관지평고DAI적손상정도.
Objective To study the sensitivity of diffusion tensor imaging (DTI) in diagnosing diffuse axon injury (DAI) and research the correlation between fractional anisotropy (FA) values of midbrain and Glasgow coma scale (GCS) scores to quantitative evaluate DAI.Methods One hundred and five patients with DAI,admitted to our hospital from 2007 to 2013,were chosen in our study; their imaging data,including X-ray computed tomography (CT) scan,magnetic resonance imaging (MRI)conventional scan and DTI scan at admission,were observed,and the sensitivity of three imaging methods in detecting DAI damage lesions was compared; the correlation between FA values in the midbrain and GCS scores of 36 DAI patients was analyzed.Results The sensitivity of CT in detecting DAI damage lesions was 70.48％,that of MRI conventional scan was 82.86％ and that of DTI scan was 95.24％ with significant difference among the three groups (P＜0.05).Significant positive correlation was noted between GCS scores and FA values of midbrain areas (r=0.977,P=0.000).Conclusion As to DTI in the diagnosis of DAI,not only its sensitivity is superior to CT and MRI scan,but also in a certain extent it can objectively evaluate the injury extent of DAI.
