CAJ | 학술논문

目的利用MRI影像Flair序列和虚拟现实系统构建侧脑室周围核团三维解剖模型,观察各解剖结构之间的空间形态和毗邻关系. 方法将成年尸体头颅进行T2 Flair序列扫描,获得Dicom数据输入Vitrea虚拟现实工作站,构建侧脑室、尾状核、壳核、苍白球外侧部、苍白球内侧部、海马、杏仁核等交互式三维解剖模型并且进行解剖观察. 结果 Flair影像中神经核团以及脑室与周围组织图像对比度良好,大脑皮质和除红核、丘脑底核之外的神经核团呈现高信号,红核呈现卵圆形略低信号,丘脑底核呈双凸透镜略低信号,大脑白质、脑室和脑沟呈现低信号,便于图像分割.虚拟现实模型三维可视化效果良好,侧脑室和周围核团空间形态和毗邻关系显示清晰,通过图像旋转和透明度调节,能够多角度、多层次、非侵袭性地进行解剖观察. 结论利用Flair成像结合虚拟现实技术构建侧脑室周围核团三维解剖模型有助于无创直观地观察和理解脑神经核团的整体空间关系,节约时间和标本,并可为指导相关手术提供充分的解剖依据.
목적 이용MRI영상Flair서렬화허의현실계통구건측뇌실주위핵단삼유해부모형,관찰각해부결구지간적공간형태화비린관계. 방법 장성년시체두로진행T2 Flair서렬소묘,획득Dicom수거수입Vitrea허의현실공작참,구건측뇌실、미상핵、각핵、창백구외측부、창백구내측부、해마、행인핵등교호식삼유해부모형병차진행해부관찰. 결과 Flair영상중신경핵단이급뇌실여주위조직도상대비도량호,대뇌피질화제홍핵、구뇌저핵지외적신경핵단정현고신호,홍핵정현란원형략저신호,구뇌저핵정쌍철투경략저신호,대뇌백질、뇌실화뇌구정현저신호,편우도상분할.허의현실모형삼유가시화효과량호,측뇌실화주위핵단공간형태화비린관계현시청석,통과도상선전화투명도조절,능구다각도、다층차、비침습성지진행해부관찰. 결론 이용Flair성상결합허의현실기술구건측뇌실주위핵단삼유해부모형유조우무창직관지관찰화리해뇌신경핵단적정체공간관계,절약시간화표본,병가위지도상관수술제공충분적해부의거.
Objective To establish three-dimensional anatomic models of nucleus surrounding the lateral ventricle by utilizing MRI data of Flair sequence and virtual reality system,and then,observe the spacial form and relationships of above anatomic structures.Methods MRI scan of T2 Flair sequence was performed to adult cadaver heads,of which Digital Imaging and Communications in Medicine data was inputted into the Vitrea virtual reality workstation to build interactive three-dimensional anatomic models of lateral ventrical,caudate nucleus,putamen,external segment of globus pallidus,internal segment of globus pallidus,hippocampus,amygdala,mamillary body,thalamus,subthalamus nucleus,red nucleus,and substantia nigra.Anatomic observation was performed for above structures.Results High resolution was achieved to distinguish lateral ventrical and surrounding nucleus from remaining tissues.In the image of Flair sequence,cerebral cortex and other nucleus,except red nucleus and subthalamus nucleus,demonstrated high signal; red nucleus and subthalamus nucleus showed slight low signal oval and len form,respectively; white matter,ventricle and brain sulcus demonstrated low signal.Procedures of image segmentation were convenient.Three-dimensional visualization effect of virtual reality models were well,of which spacial form and relationships displayed clearly.Lateral ventrical and surrounding nucleus were observed with multiple visual angles,multiple levels and non-invasive way by rotating model and modulating transparency.Conclusion Three-dimensional anatomic models of nucleus surrounding lateral ventricle simulated by Flair image combined with virtual reality technique is helpful in observing and understanding the global spacial relationship of nucleus non-invasively and objectively; the procedure is time-and specimen-saving and provides reliable information for relative surgery.