中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2014年
2期
188-190
,共3页
大脑中动脉狭窄或闭塞%二氧化碳吸入%SPECT%脑血管储备力
大腦中動脈狹窄或閉塞%二氧化碳吸入%SPECT%腦血管儲備力
대뇌중동맥협착혹폐새%이양화탄흡입%SPECT%뇌혈관저비력
Middle cerebral artery steno-occlusion%CO2 inhalation text%Single-photon emission computed tomography%Cerebrovascular reserve
目的 用单光子发射计算机断层扫描(SPECT)结合二氧化碳(CO2)负荷试验评价大脑中动脉(MCA)狭窄或闭塞患者的脑血管储备力(CVR). 方法 选择自2010年10月至2012年3月间在空军总院神经内科住院的MCA狭窄或闭塞患者,CO2负荷试验前后分别行SPECT检查.设定12个感兴趣区(ROI),左右对称6个,计算各感兴趣区的平均局部脑血流量比值(rCBF％),比较正常侧与患侧rCBF％的差值及CO2吸入试验前后各ROI的rCBF％变化评价CVR. 结果 24例患者中有2例CVR正常.CO2负荷前后rCBF％均正常的ROI有121个;CO2负荷试验前rCBF％正常,负荷试验后减低的ROI有1 19个;CO2负荷试验前rCBF％减低,负荷试验后减低更明显的ROI有12个;另有38个ROI CO2负荷试验前rCBF％减低,负荷试验后较前升高. 结论 单侧MCA狭窄或闭塞患者中存在着CVR正常者.MCA狭窄或闭塞后脑血管对CO2负荷试验存在不同的反应性.
目的 用單光子髮射計算機斷層掃描(SPECT)結閤二氧化碳(CO2)負荷試驗評價大腦中動脈(MCA)狹窄或閉塞患者的腦血管儲備力(CVR). 方法 選擇自2010年10月至2012年3月間在空軍總院神經內科住院的MCA狹窄或閉塞患者,CO2負荷試驗前後分彆行SPECT檢查.設定12箇感興趣區(ROI),左右對稱6箇,計算各感興趣區的平均跼部腦血流量比值(rCBF％),比較正常側與患側rCBF％的差值及CO2吸入試驗前後各ROI的rCBF％變化評價CVR. 結果 24例患者中有2例CVR正常.CO2負荷前後rCBF％均正常的ROI有121箇;CO2負荷試驗前rCBF％正常,負荷試驗後減低的ROI有1 19箇;CO2負荷試驗前rCBF％減低,負荷試驗後減低更明顯的ROI有12箇;另有38箇ROI CO2負荷試驗前rCBF％減低,負荷試驗後較前升高. 結論 單側MCA狹窄或閉塞患者中存在著CVR正常者.MCA狹窄或閉塞後腦血管對CO2負荷試驗存在不同的反應性.
목적 용단광자발사계산궤단층소묘(SPECT)결합이양화탄(CO2)부하시험평개대뇌중동맥(MCA)협착혹폐새환자적뇌혈관저비력(CVR). 방법 선택자2010년10월지2012년3월간재공군총원신경내과주원적MCA협착혹폐새환자,CO2부하시험전후분별행SPECT검사.설정12개감흥취구(ROI),좌우대칭6개,계산각감흥취구적평균국부뇌혈류량비치(rCBF％),비교정상측여환측rCBF％적차치급CO2흡입시험전후각ROI적rCBF％변화평개CVR. 결과 24례환자중유2례CVR정상.CO2부하전후rCBF％균정상적ROI유121개;CO2부하시험전rCBF％정상,부하시험후감저적ROI유1 19개;CO2부하시험전rCBF％감저,부하시험후감저경명현적ROI유12개;령유38개ROI CO2부하시험전rCBF％감저,부하시험후교전승고. 결론 단측MCA협착혹폐새환자중존재착CVR정상자.MCA협착혹폐새후뇌혈관대CO2부하시험존재불동적반응성.
Objective To evaluate the cerebrovascular reserve (CVR) of patients with unilateral middle cerebral artery (MCA) steno-occlusion with single-photon emission computed tomography (SPECT) and CO2 inhalation test.Methods SPECT were performed in patients diagnosed as having unilateral MCA steno-occlusion disease in our hospital from October 2010 to March 2012.SPECT were performed in 24 unilateral MCA steno-occlusion patients before and after CO2 inhalation text.Twelve regions of interests (ROIs),6 in the right and 6 in the left,were chosen in each patient; the ratio of regional cerebral blood flow (rCBF％) of all ROIs were calculated,compared between the normal side and the steno-occlusive side,and before and after CO2 inhalation test for CVR.Results Two of 24 patients had normal CVR.And there were four types of cerebrovascular reactivity to CO2:the first,there were no differences ofrCBF％ before and after CO2 inhalation text in 121 ROIs; the sencond,rCBF％ was normal before the CO2 inhalation text and then decreased after the test in 119 ROIs; the third,rCBF％ was decreased before the CO2 inhalation text and then further decreased after the text in 12 ROIs; and the forth,rCBF％ was decreased before the CO2 inhalation text and increased after the text in 72 ROIs.Conclusion There is normal CVR in patients with unilateral middle cerebral artery steno-occlusion;there are four reactions for CVR in patients with unilateral middle cerebral artery steno-occlusive.
