中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2014年
5期
518-521
,共4页
头痛%药物过量%临床特点%复合止痛剂%致残性
頭痛%藥物過量%臨床特點%複閤止痛劑%緻殘性
두통%약물과량%림상특점%복합지통제%치잔성
Headache%Medication overuse%Clinical characteristic%Combination analgesic%Disability
目的 探讨药物过量性头痛(MOH)患者的不同病因及临床特征,加强该病的临床重视程度及患者用药安全意识. 方法 总结分析自2011年8月至2012年3月在吉林大学第二医院神经内科头痛门诊诊治的88例MOH患者人口学特点、头痛特点、伴发症状及致残情况. 结果 MOH患者平均年龄为(47.0±10.5)岁,约80％为女性,98％为中重度头痛,头痛部位在全头和颞顶部的为39％,头痛性质为跳痛、胀痛的各占51％和42％;近70％伴发睡眠障碍,近50％平日情绪烦躁,近20％伴有情绪低落;63.15％和73.68％ MOH患者的偏头痛残疾程度评估问卷、头痛影响测试评分显示致残程度为重度.过量服用的药物种类包括非甾体类抗炎药与咖啡因的复合止痛剂、中成药、单组份的非甾体类抗炎药,其中非甾体类抗炎药与咖啡因的复合止痛剂占86％. 结论 MOH好发于中老年女性慢性偏头痛患者,程度较重,易伴发精神、睡眠障碍,严重影响生活.
目的 探討藥物過量性頭痛(MOH)患者的不同病因及臨床特徵,加彊該病的臨床重視程度及患者用藥安全意識. 方法 總結分析自2011年8月至2012年3月在吉林大學第二醫院神經內科頭痛門診診治的88例MOH患者人口學特點、頭痛特點、伴髮癥狀及緻殘情況. 結果 MOH患者平均年齡為(47.0±10.5)歲,約80％為女性,98％為中重度頭痛,頭痛部位在全頭和顳頂部的為39％,頭痛性質為跳痛、脹痛的各佔51％和42％;近70％伴髮睡眠障礙,近50％平日情緒煩躁,近20％伴有情緒低落;63.15％和73.68％ MOH患者的偏頭痛殘疾程度評估問捲、頭痛影響測試評分顯示緻殘程度為重度.過量服用的藥物種類包括非甾體類抗炎藥與咖啡因的複閤止痛劑、中成藥、單組份的非甾體類抗炎藥,其中非甾體類抗炎藥與咖啡因的複閤止痛劑佔86％. 結論 MOH好髮于中老年女性慢性偏頭痛患者,程度較重,易伴髮精神、睡眠障礙,嚴重影響生活.
목적 탐토약물과량성두통(MOH)환자적불동병인급림상특정,가강해병적림상중시정도급환자용약안전의식. 방법 총결분석자2011년8월지2012년3월재길림대학제이의원신경내과두통문진진치적88례MOH환자인구학특점、두통특점、반발증상급치잔정황. 결과 MOH환자평균년령위(47.0±10.5)세,약80％위녀성,98％위중중도두통,두통부위재전두화섭정부적위39％,두통성질위도통、창통적각점51％화42％;근70％반발수면장애,근50％평일정서번조,근20％반유정서저락;63.15％화73.68％ MOH환자적편두통잔질정도평고문권、두통영향측시평분현시치잔정도위중도.과량복용적약물충류포괄비치체류항염약여가배인적복합지통제、중성약、단조빈적비치체류항염약,기중비치체류항염약여가배인적복합지통제점86％. 결론 MOH호발우중노년녀성만성편두통환자,정도교중,역반발정신、수면장애,엄중영향생활.
Objective To investigate the clinical features of medication overuse headache (MOH) to provide data for the diagnosis and treatment of MOH.Methods Eighty-eight patients with MOH,admitted to our hospital from August 2011 to March 2012,were chosen in our study; the demographic characteristics,headache characteristics,concomitant symptoms and disability of these patients were analyzed statistically.Results MOH patients (aged 47.0±17.5 years and 80％ being women) had the following characteristics:moderate to severe pain (98％),throbbing or distending pain (51％ and 42％,respectively),locating in full head or temporal top,sleep disorders (70％),emotional irritability (50％) and depression (20％).Migraine Disability Assessment Questionnaire showed that about 63.15％ patients had severe degree of disability and Headache Impact Test (HIT-6) indicated about 73.68％ patients.The over-used medication was combination analgesic,including non-steroid anti-inflammatory drug and caffeine in 76 patients (86％),Chinese patent drug in 10 patients (12％) and non-steroid anti-inflammatory drug in 2 patients (2％).Conclusion Most MOH patients are old women with chronic migraine,whose typical characteristics of headache are moderate to severe throbbing or distending pain in full head or temporal top,often accompanied with depression,dysphoria and sleeplessness,which affects life deeply.
