中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2014年
6期
543-546
,共4页
帕金森病%深部脑刺激%丘脑底核%三维重建
帕金森病%深部腦刺激%丘腦底覈%三維重建
파금삼병%심부뇌자격%구뇌저핵%삼유중건
Parkinson's disease%Deep brain stimulation%Subthalamic nucleus%Three-dimensional reconstruction
目的 通过应用丘脑底核(STN)的三维重建图获取更理想的穿刺角度,使电极通过核团的长度进一步延长. 方法 通过第三军医大学的中国数字化可视人体数据库中1例22岁女性模板重建了脑深部核团的3D图谱,并对其STN核团参数进行了测量.同时将回顾性分析的30例患者MRI图像信息同3D图谱的结果进行融合对比,获得MRI核团信息. 结果 3D图谱中STN的空间角度参数同30例患者影像资料数据间的差异小(差值的95％CI范围＜1),提示图谱的代表性好.在图谱上经过模拟电极测量得出推荐穿刺角度,即环角/侧角为:55°～57°/17°～19°,核团内部电极长度为(5.7±0.3)mm. 结论 3D图谱在脑深部核团的定位上具有较高的代表性,与个体的影像结果可以很好地融合;通过在图谱上进行测量可得出针道的适合穿刺角度组合,获得更长的核团内电极长度.
目的 通過應用丘腦底覈(STN)的三維重建圖穫取更理想的穿刺角度,使電極通過覈糰的長度進一步延長. 方法 通過第三軍醫大學的中國數字化可視人體數據庫中1例22歲女性模闆重建瞭腦深部覈糰的3D圖譜,併對其STN覈糰參數進行瞭測量.同時將迴顧性分析的30例患者MRI圖像信息同3D圖譜的結果進行融閤對比,穫得MRI覈糰信息. 結果 3D圖譜中STN的空間角度參數同30例患者影像資料數據間的差異小(差值的95％CI範圍＜1),提示圖譜的代錶性好.在圖譜上經過模擬電極測量得齣推薦穿刺角度,即環角/側角為:55°～57°/17°～19°,覈糰內部電極長度為(5.7±0.3)mm. 結論 3D圖譜在腦深部覈糰的定位上具有較高的代錶性,與箇體的影像結果可以很好地融閤;通過在圖譜上進行測量可得齣針道的適閤穿刺角度組閤,穫得更長的覈糰內電極長度.
목적 통과응용구뇌저핵(STN)적삼유중건도획취경이상적천자각도,사전겁통과핵단적장도진일보연장. 방법 통과제삼군의대학적중국수자화가시인체수거고중1례22세녀성모판중건료뇌심부핵단적3D도보,병대기STN핵단삼수진행료측량.동시장회고성분석적30례환자MRI도상신식동3D도보적결과진행융합대비,획득MRI핵단신식. 결과 3D도보중STN적공간각도삼수동30례환자영상자료수거간적차이소(차치적95％CI범위＜1),제시도보적대표성호.재도보상경과모의전겁측량득출추천천자각도,즉배각/측각위:55°～57°/17°～19°,핵단내부전겁장도위(5.7±0.3)mm. 결론 3D도보재뇌심부핵단적정위상구유교고적대표성,여개체적영상결과가이흔호지융합;통과재도보상진행측량가득출침도적괄합천자각도조합,획득경장적핵단내전겁장도.
Objective To measure the parameters of the specific electrode trajectory angles under the condition that the trajectory length in the nuclei could be as long as possible by using 3D reconstruction of subthalamic nucleus (STN).Methods A 3D atlas of deep brain nuclei was built on the 3D reconstruction station,and the parameters of STN were measured.MR imaging of 30 Parkinson's disease (PD) patients was matched to the 3D atlas to acquire the average nucleus information.Results The STN spatial location parameters showed no significant statistical difference with imaging of these 30 patients (95％ confidence interval of difference value＜l),indicating that this 3D atlas enjoyed good representative value.After simulation,the optimal trajectory angles were achieved:the combination angles ofring/slide:55°-57°/17°-19°,which extended the trajectory within the nucleus to about (5.7±0.3)mm.Conclusion The 3D atlas shows high representative of locating deep brain nucleus and could be registrated well to particular patient's images.After simulation on the atlas,the optimal trajectory angles parameters can be obtained,which shows the specific operation of achieving longer length of electrode in nucleus.
