CAJ | 학술논문

目的评价甲钴胺治疗对后交通动脉瘤性动眼神经麻痹患者栓塞术后恢复情况的影响. 方法湖北医药学院附属襄阳医院神经科自2007年7月至2013年1月收治后交通动脉瘤合并动眼神经麻痹患者56例,随访55例,其中27例行单纯动脉瘤栓塞术,28例行动脉瘤栓塞术+甲钴胺治疗,随访并比较患者术后1年动眼神经麻痹恢复情况. 结果全部患者随访1年以上.55例患者中31例动眼神经完全恢复(56.4％),19例部分恢复(34.5％),5例(9.1％)无恢复;其中动脉瘤栓塞术+甲钴胺治疗组完全恢复20例(71.4％),单纯动脉瘤栓塞术治疗组完全恢复11例(40.7％),比较差异有统计学意义(P＜0.05). 结论栓塞术结合甲钴胺治疗能促进后交通动脉瘤性动眼神经麻痹的恢复.
목적 평개갑고알치료대후교통동맥류성동안신경마비환자전새술후회복정황적영향. 방법 호북의약학원부속양양의원신경과자2007년7월지2013년1월수치후교통동맥류합병동안신경마비환자56례,수방55례,기중27례행단순동맥류전새술,28례행동맥류전새술+갑고알치료,수방병비교환자술후1년동안신경마비회복정황. 결과 전부환자수방1년이상.55례환자중31례동안신경완전회복(56.4％),19례부분회복(34.5％),5례(9.1％)무회복;기중동맥류전새술+갑고알치료조완전회복20례(71.4％),단순동맥류전새술치료조완전회복11례(40.7％),비교차이유통계학의의(P＜0.05). 결론 전새술결합갑고알치료능촉진후교통동맥류성동안신경마비적회복.
Objective To describe the evolution of oculomotor nerve paresis (ONP) after endovascular packing of posterior communicating artery aneurysms (PcomA) to prospectively evaluate the effect of mecobalamine treatment on ONP prospective recovery.Methods A total of 56 patients with ONP attributable to PcomA,treated with coils in our hospital from July 2007 to January 2013,were enrolled in a randomized,controlled open study,and 55 of them got follow up;embolization+mecobalamine treatment was performed in 28 and embolization treatment was in 27.The degrees of ONP were recorded one year after treatment.Results All patients succeeded in one year follow-up; 31 patients (56.4％) achieved complete resolution of ONP,19 (34.5％) partial improvement and 5 (9.1％) no changes.The complete recovery rate in the embolization+mecobalamine treatment group was 71.4％ (20/28) and that in the embolization treatment group was 40.7％ (11/27),with statistically significant differences (P＜0.05).Conclusion Endovascular treatment is highly efficacious in treating ONP-inducing PcomA and mecobalamine treatment can promote the recovery of oculomotor nerve palsy after embolism.