中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2014年
8期
812-816
,共5页
张隆辉%高天%李冬梅%杜世伟%汪晶%白志峰%毛更生
張隆輝%高天%李鼕梅%杜世偉%汪晶%白誌峰%毛更生
장륭휘%고천%리동매%두세위%왕정%백지봉%모경생
吲哚菁绿%血管荧光造影%颅内动脉瘤%定量分析
吲哚菁綠%血管熒光造影%顱內動脈瘤%定量分析
신타정록%혈관형광조영%로내동맥류%정량분석
Indocyanine green%Fluorescein angiography%Aneurysm%Quantitative analysis
目的 尝试用动脉瘤夹闭术中吲哚菁绿血管荧光造影定量分析方法对动脉瘤夹闭效果进行分析评价. 方法 选择武警总医院神经血管外科自2012年9月至2013年9月在动脉瘤夹闭术中辅助应用吲哚菁绿血管荧光造影的20例颅内动脉瘤患者(6例前交通动脉瘤,5例后交通动脉瘤,9例大脑中动脉动脉瘤),截取夹闭前后的造影视频图像,选取图像中相同部位(动脉瘤区、载瘤动脉区、分支动脉区)的兴趣点,利用定量分析的方法得出荧光强度曲线达峰时间并进行比较. 结果 动脉瘤区兴趣点夹闭前平均达峰时间为(10.975±1.208)s,夹闭后为(47.950±2.350)s,比较差异有统计学意义(t=57.299,P=0.000);载瘤动脉区兴趣点夹闭前平均达峰时间为(10.600±1.619)s,夹闭后为(10.350±1.452)s,比较差异无统计学意义(t=0.641,P=0.529);分支动脉区兴趣点夹闭前平均达峰时间为(10.400±1.153)s,夹闭后为(10.425±1.311)s,比较差异无统计学意义(t=-0.079,P=0.938). 结论 吲哚菁绿血管荧光造影定量分析可从血流量层面上对动脉瘤夹闭结果进行可靠判断,增加手术成功率.
目的 嘗試用動脈瘤夾閉術中吲哚菁綠血管熒光造影定量分析方法對動脈瘤夾閉效果進行分析評價. 方法 選擇武警總醫院神經血管外科自2012年9月至2013年9月在動脈瘤夾閉術中輔助應用吲哚菁綠血管熒光造影的20例顱內動脈瘤患者(6例前交通動脈瘤,5例後交通動脈瘤,9例大腦中動脈動脈瘤),截取夾閉前後的造影視頻圖像,選取圖像中相同部位(動脈瘤區、載瘤動脈區、分支動脈區)的興趣點,利用定量分析的方法得齣熒光彊度麯線達峰時間併進行比較. 結果 動脈瘤區興趣點夾閉前平均達峰時間為(10.975±1.208)s,夾閉後為(47.950±2.350)s,比較差異有統計學意義(t=57.299,P=0.000);載瘤動脈區興趣點夾閉前平均達峰時間為(10.600±1.619)s,夾閉後為(10.350±1.452)s,比較差異無統計學意義(t=0.641,P=0.529);分支動脈區興趣點夾閉前平均達峰時間為(10.400±1.153)s,夾閉後為(10.425±1.311)s,比較差異無統計學意義(t=-0.079,P=0.938). 結論 吲哚菁綠血管熒光造影定量分析可從血流量層麵上對動脈瘤夾閉結果進行可靠判斷,增加手術成功率.
목적 상시용동맥류협폐술중신타정록혈관형광조영정량분석방법대동맥류협폐효과진행분석평개. 방법 선택무경총의원신경혈관외과자2012년9월지2013년9월재동맥류협폐술중보조응용신타정록혈관형광조영적20례로내동맥류환자(6례전교통동맥류,5례후교통동맥류,9례대뇌중동맥동맥류),절취협폐전후적조영시빈도상,선취도상중상동부위(동맥류구、재류동맥구、분지동맥구)적흥취점,이용정량분석적방법득출형광강도곡선체봉시간병진행비교. 결과 동맥류구흥취점협폐전평균체봉시간위(10.975±1.208)s,협폐후위(47.950±2.350)s,비교차이유통계학의의(t=57.299,P=0.000);재류동맥구흥취점협폐전평균체봉시간위(10.600±1.619)s,협폐후위(10.350±1.452)s,비교차이무통계학의의(t=0.641,P=0.529);분지동맥구흥취점협폐전평균체봉시간위(10.400±1.153)s,협폐후위(10.425±1.311)s,비교차이무통계학의의(t=-0.079,P=0.938). 결론 신타정록혈관형광조영정량분석가종혈류량층면상대동맥류협폐결과진행가고판단,증가수술성공솔.
Objective Indocyanine green (ICG) video angiography is widely used in aneurysm surgery.This study is to evaluate and analyze the effect of intraoperatively aneurysms clipping by quantitative analysis of ICG video angiography.Methods Twenty patients with cerebral aneurysms (six with anterior communicating artery aneurysms,five with communicating artery aneurysms and nine with middle cerebral artery aneurysms),admitted to our hospital from September 2012 to September 2013,were chosen in our study; they all underwent aneurysms clipping involving ICG.Same areas of interest (AOIs,aneurysm area,parent artery area and branch artery area) of images intercepted from angiogram videos before and after clipping of aneurysms were analyzed by Image-pro plus.Results Dramatic differences in time to peak of blood flow of aneurysm areas were observed before and after clipping of aneurysms ([10.975±1.208] s vs.[47.950±2.350] s,t=57.299,P=0.000).There were no dramatic differences in times to peak of blood flow of parent and branch vessels before aneurysms clipping and after aneurysms clipping ([10.600±1.619] svs.[10.350±1.452] s,t=0.641,P=0.529;[10.400±1.153] s vs.[10.425±1.311] s,t=-0.079,P=0.938).Conclusion Quantitative analysis is a good method to evaluate the effect of aneurysm clipping surgery according to the blood flow,which might improve the success rate.
