中华烧伤杂志
中華燒傷雜誌
중화소상잡지
16
2013年
4期
374-377
,共4页
微小RNA%创面愈合
微小RNA%創麵愈閤
미소RNA%창면유합
MicroRNA%Wound healing
MicroRNAs are endogenous noncoding RNA molecules with 19-22 nucleotides in length.MicroRNAs can post-transcriptionally regulate gene and (or) protein expression by binding to their target messenger RNAs (mRNAs),leading to mRNA degradation or suppression of translation.As a huge family that regulates gene expression,microRNAs has recently been shown to not only participate in the normal healing processes of wounds but also closely related to pathologic wound healing,and formation of hypertrophic scars and keloids.This review focuses on the biogenesis of microRNA and its role in wound healing.