中华烧伤杂志
中華燒傷雜誌
중화소상잡지
16
2014年
2期
134-137
,共4页
刘玲英%柴家科%郁永辉%侯玉森
劉玲英%柴傢科%鬱永輝%侯玉森
류령영%시가과%욱영휘%후옥삼
伤口愈合%间质干细胞%细胞增殖%细胞分化%旁分泌
傷口愈閤%間質榦細胞%細胞增殖%細胞分化%徬分泌
상구유합%간질간세포%세포증식%세포분화%방분비
Wound healing%Mesenchymal stem cells%Cell proliferation%Cell differentiation%Paracrine
Wound healing is a dynamic and complicated process,which generally takes three overlapping phases:inflammation,proliferation,and remodeling.If wounds complicated by severe trauma,diabetes,vascular dysfunction disease,or a massive burn injury failed to pass through the three normal phases of healing,they might end up as chronic and refractory wounds.Mesenchymal stem cells (MSCs) play different important roles in the regulation of all the phases of wound healing.MSCs can be recruited into wound and differentiated into wound repair cells,as well as promote wound healing by exerting functions like anti-inflammation,anti-apoptosis,and neovascularization.This review focuses on the role and mechanism of MSCs in each phase of the wound healing process.
