中华实验和临床病毒学杂志
中華實驗和臨床病毒學雜誌
중화실험화림상병독학잡지
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY
2014年
2期
93-95
,共3页
朱冰%欧阳灿%刘鸿凌%臧红%荣义辉%万志红%游绍莉%辛绍杰
硃冰%歐暘燦%劉鴻凌%臧紅%榮義輝%萬誌紅%遊紹莉%辛紹傑
주빙%구양찬%류홍릉%장홍%영의휘%만지홍%유소리%신소걸
肝衰竭%降钙素%C反应蛋白
肝衰竭%降鈣素%C反應蛋白
간쇠갈%강개소%C반응단백
liver failure%Calcitonin%C-reactive protein
目的 探讨C反应蛋白和降钙素原对乙肝肝衰竭患者合并感染的诊断价值.方法 对我院收治的162例乙肝肝衰竭患者分为感染组和非感染组,检测白细胞、C反应蛋白、降钙素原,绘制ROC曲线,进行统计分析.结果 感染组与非感染组WBC、CRP、PCT差异有统计学意义(P＜0.05),WBC、CRP、PCT的ROC曲线下面积分别为0.816,0.802,0.818,感染诊断阳性标准分别为WBC＞ 9.53×109/L、PCT＞0.622 ng/ml、CRP＞ 27 mg/l,敏感度和特异性分别为63.56％和93.18％,55.93％和93.18％,80.51％和70.45％.结论 WBC、CRP、PCT为乙肝肝衰竭患者合并感染的可靠诊断指标,PCT对感染诊断具有较强的敏感性,WBC、CRP特异性较高,综合分析有利于准确判断感染的发生.
目的 探討C反應蛋白和降鈣素原對乙肝肝衰竭患者閤併感染的診斷價值.方法 對我院收治的162例乙肝肝衰竭患者分為感染組和非感染組,檢測白細胞、C反應蛋白、降鈣素原,繪製ROC麯線,進行統計分析.結果 感染組與非感染組WBC、CRP、PCT差異有統計學意義(P＜0.05),WBC、CRP、PCT的ROC麯線下麵積分彆為0.816,0.802,0.818,感染診斷暘性標準分彆為WBC＞ 9.53×109/L、PCT＞0.622 ng/ml、CRP＞ 27 mg/l,敏感度和特異性分彆為63.56％和93.18％,55.93％和93.18％,80.51％和70.45％.結論 WBC、CRP、PCT為乙肝肝衰竭患者閤併感染的可靠診斷指標,PCT對感染診斷具有較彊的敏感性,WBC、CRP特異性較高,綜閤分析有利于準確判斷感染的髮生.
목적 탐토C반응단백화강개소원대을간간쇠갈환자합병감염적진단개치.방법 대아원수치적162례을간간쇠갈환자분위감염조화비감염조,검측백세포、C반응단백、강개소원,회제ROC곡선,진행통계분석.결과 감염조여비감염조WBC、CRP、PCT차이유통계학의의(P＜0.05),WBC、CRP、PCT적ROC곡선하면적분별위0.816,0.802,0.818,감염진단양성표준분별위WBC＞ 9.53×109/L、PCT＞0.622 ng/ml、CRP＞ 27 mg/l,민감도화특이성분별위63.56％화93.18％,55.93％화93.18％,80.51％화70.45％.결론 WBC、CRP、PCT위을간간쇠갈환자합병감염적가고진단지표,PCT대감염진단구유교강적민감성,WBC、CRP특이성교고,종합분석유리우준학판단감염적발생.
Objective To investigate the diagnostic value of proealeitonin (PCT) and C-reactive protein(CRP) test in the patients with hepatitis B virus acute-on-chronic liver failure (HBV-ACLF).Methods 162 cases of hepatitis B virus acute-on-chronic liver failure patients were divided into infection group and non-infection group.The level of serum PCT and CRP was detected.The results were analyzed by using the ROC of the participants.Results The levels of WBC,PCT,CRP showed significant differences among the groups(P ＜0.05).Area under curve of ROC of WBC,CRP,PCT were 0.816,0.802,0.818.At a cut off level of WBC ＞ 9.53 × 109/L,PCT ＞ 0.622ng/ml,CRP ＞ 27 mg/L,the sensitivity and the specificity were 63.56％ and 93.18％,55.93％ and 93.18％,80.51％ and 70.45％ respectively.Conclusion WBC,PCT and CRP were prospective marker of bacterial infection in HBV-ACLF patients with infection.PCT has a strong sensitivity for diagnosis of infection,WBC and CRP have hig specificity.Comprehensive analysis is conducive to accurately determine the incidence of infection.
