中华实验和临床病毒学杂志
中華實驗和臨床病毒學雜誌
중화실험화림상병독학잡지
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY
2014年
4期
274-276
,共3页
麻疹%免疫学监视
痳疹%免疫學鑑視
마진%면역학감시
Measles%Immunologic surveillance
目的 分析曹县麻疹病例实验室检测结果、流行病学和临床特点,为当地预防控制麻疹提供指导.方法 从国家疾病监测信息报告管理系统收集2009-2013年曹县麻疹疫情数据,以及麻疹疑似病例,开展麻疹IgM、风疹IgM检测和分析麻疹病毒分离情况、病例特点.结果 2009-2013年度共报告227例麻疹疑似病例,血清标本采集率72.69%,麻疹IgM阳性率为18.71%,12例咽拭子标本中分离出5株麻疹病毒,为H1a基因型.确诊168例麻疹病例,<4岁年龄组的构成比为80.95%,幼托儿童、散居儿童是麻疹发病的主要人群,占89.29%;主要临床表现包括发热,超过38.5℃者占86.63%,皮疹首发部位为面部,占72.95%,有口腔黏膜斑者占72.80%,麻疹并发症前三位分别为肺炎、心肌炎、喉炎.结论 经血清学和病毒学证实,曹县当地存在麻疹病毒传播,病例以散发为主,麻疹野病毒为H1基因型,麻疹发病与年龄、性别、职业、季节有关.
目的 分析曹縣痳疹病例實驗室檢測結果、流行病學和臨床特點,為噹地預防控製痳疹提供指導.方法 從國傢疾病鑑測信息報告管理繫統收集2009-2013年曹縣痳疹疫情數據,以及痳疹疑似病例,開展痳疹IgM、風疹IgM檢測和分析痳疹病毒分離情況、病例特點.結果 2009-2013年度共報告227例痳疹疑似病例,血清標本採集率72.69%,痳疹IgM暘性率為18.71%,12例嚥拭子標本中分離齣5株痳疹病毒,為H1a基因型.確診168例痳疹病例,<4歲年齡組的構成比為80.95%,幼託兒童、散居兒童是痳疹髮病的主要人群,佔89.29%;主要臨床錶現包括髮熱,超過38.5℃者佔86.63%,皮疹首髮部位為麵部,佔72.95%,有口腔黏膜斑者佔72.80%,痳疹併髮癥前三位分彆為肺炎、心肌炎、喉炎.結論 經血清學和病毒學證實,曹縣噹地存在痳疹病毒傳播,病例以散髮為主,痳疹野病毒為H1基因型,痳疹髮病與年齡、性彆、職業、季節有關.
목적 분석조현마진병례실험실검측결과、류행병학화림상특점,위당지예방공제마진제공지도.방법 종국가질병감측신식보고관리계통수집2009-2013년조현마진역정수거,이급마진의사병례,개전마진IgM、풍진IgM검측화분석마진병독분리정황、병례특점.결과 2009-2013년도공보고227례마진의사병례,혈청표본채집솔72.69%,마진IgM양성솔위18.71%,12례인식자표본중분리출5주마진병독,위H1a기인형.학진168례마진병례,<4세년령조적구성비위80.95%,유탁인동、산거인동시마진발병적주요인군,점89.29%;주요림상표현포괄발열,초과38.5℃자점86.63%,피진수발부위위면부,점72.95%,유구강점막반자점72.80%,마진병발증전삼위분별위폐염、심기염、후염.결론 경혈청학화병독학증실,조현당지존재마진병독전파,병례이산발위주,마진야병독위H1기인형,마진발병여년령、성별、직업、계절유관.
Objective To analyze the detection results of measles serum samples,the epidemic and clinical characteristics of measles cases so as to provide guidance for local prevention and control measles.Methods From the national disease surveillance information management system,the data of Caoxian measles epidemic,combined measles IgM and rubella IgM detection and isolation of measles virus of the suspected measles cases were conducted,and the epidemiological characteristics and classification of the cases were observed.Results A total of 227 cases of suspected cases of measles were reported,and serum sample collection rate of measles suspected cases was 72.69% with the positive rate of measles IgM 18.71%,in 12 cases of throat swab specimens,5 strains of measles virus were isolated,genotype H1a confirmed.In all suspected measles cases,the people without measles vaccination reached 49.78%.168 cases were confirmed measles,and of which,the constituent ratios of the groups aged under < 4 years were 80.95%.Preschool children and scattered children were the main group of measles,accounting for 89.29%.The main clinical manifestations included fever,more than 38.5℃ accounting for 86.63%,rash starting positions for the face accounting for 72.95%,with oral mucosal patches accounting for 72.80%.The top three complications of measles were pneumonia,myocarditis,Laryngitis.Conclusion Measles incidence was related with age,gender,occupation,season,mainly in sporadic.The measles virus was H1 genotype.