CAJ | 학술논문

目的检测骨骼肌组织学的变化,探讨不同修复方式对失神经骨骼肌的影响.方法将32只普通级SD大鼠左上肢肌皮神经切断,随机分成2组,非神经寄养组(16只)；神经寄养组(16只),将胸内侧神经分支的近端移位于寄养组肌皮神经的远端,6周后对两组大鼠行二期神经修复.分别于修复术后6、12周测量两组大鼠双上肢肌肉湿重和肌纤维横截面积,比较各项指标的恢复率.结果神经修复术后6、12周神经寄养组的肌肉湿重恢复率[(75.18±1.67)％、(86.41±1.53)％]和肌纤维截面积恢复率[(56.14±1.64)％、(74.83±3.54)％]均高于非神经寄养组[(48.32±2.55)％、(50.23±1.52)％和(40.32±1.54)％、(52.26±2.25)％],两组比较差异有统计学意义(P＜0.05).结论神经寄养可使肌肉保持良好状态,有利于二期神经修复.
목적 검측골격기조직학적변화,탐토불동수복방식대실신경골격기적영향.방법 장32지보통급SD대서좌상지기피신경절단,수궤분성2조,비신경기양조(16지)；신경기양조(16지),장흉내측신경분지적근단이위우기양조기피신경적원단,6주후대량조대서행이기신경수복.분별우수복술후6、12주측량량조대서쌍상지기육습중화기섬유횡절면적,비교각항지표적회복솔.결과 신경수복술후6、12주신경기양조적기육습중회복솔[(75.18±1.67)％、(86.41±1.53)％]화기섬유절면적회복솔[(56.14±1.64)％、(74.83±3.54)％]균고우비신경기양조[(48.32±2.55)％、(50.23±1.52)％화(40.32±1.54)％、(52.26±2.25)％],량조비교차이유통계학의의(P＜0.05).결론 신경기양가사기육보지량호상태,유리우이기신경수복.
Objective Through detect skeletal muscle histology,to observe the effect on nerve anastomosis of skeleta muscle by different methods.Methods The left musculocutaneous nerves were transected in 32 SD rats,then the rats were randomly divide 2 groups,babysitting group(16 rats)and nonbabysitting group (16 rats),the distal end was coapted to the purely motor medial pefctoral nerve,and reanastomosed to its proximal in babysitting group,6 weeks later; the left musculocutaneous nerves were repaired in two groups,After 6 and 12 weeks of the nerve repairation,observing the changing of the wet muscle weight and muscle fiber cross-section area on two side limbs,contrast the resule of the recovery.Results Recover of the wet muscle weight [(75.18 ± 1.67) ％,(86.41 ± 1.53) ％] and muscle fiber cross-section area of the nerve babysitting [(56.14 ± 1.64) ％,(74.83 ± 3.54) ％] is better than other groups [(48.32 ±2.55)％,(50.23 ± 1.52)％ and (40.32 ± 1.54)％,(52.26 ±2.25)％],the two aspects are significantly different from babysitting group and non-babysitting group.Conclusion Nerve babysitting can prevent muscle atrophy,and it may better to delayed nerve anastomosis.