中华实验外科杂志
中華實驗外科雜誌
중화실험외과잡지
CHINESE JOURNAL OF EXPERIMENTAL SURGERY
2013年
8期
1739-1740
,共2页
胃癌%营养支持%肠外营养%肠内营养
胃癌%營養支持%腸外營養%腸內營養
위암%영양지지%장외영양%장내영양
Gastric cancer%Nutritional support%Parenteral nutrition%Enteral nutrition
目的 探讨胃癌术后患者早期不同营养支持方法、疗效观察及应用价值.方法 将100例胃癌根治术后患者随机分为两组,分别进行全肠外营养支持(TPN组)和肠内联合肠外营养支持(CEP组),分别于术后24 h后予营养支持.观察在治疗过程中两组患者术后并发症的发生率、胃肠功能恢复时间、术后平均住院天数、免疫指标及营养评定等各项指标进行对比分析.结果 两组患者术后并发症的发生率(TPN组9％、CEP组3％)；胃肠道功能恢复时间TPN组(69.75±9.49)h、CEP组(48.54±8.46)h；平均住院时间TPN组(15.18±2.21)d、CEP组(12.89±2.23)d,CEP组明显低于TPN组(P＜0.05)；两组术后血浆总蛋白(TP)、血浆白蛋白(ALB)、血红蛋白(HGB)和体质量(BW)在营养支持后均有所下降(P＜0.05),TPN组淋巴细胞计数(LY)减少(P＜0.05),CEP组LY差异无统计学意义(P＞0.05)；两组营养及免疫指标组间差异无统计学意义(P＞0.05).结论 胃癌术后早期肠内营养联合肠外营养,在改善机体营养状况方面与全肠外营养相似,在加快免疫状态改善,降低并发症发生率方面要优于全肠外营养.
目的 探討胃癌術後患者早期不同營養支持方法、療效觀察及應用價值.方法 將100例胃癌根治術後患者隨機分為兩組,分彆進行全腸外營養支持(TPN組)和腸內聯閤腸外營養支持(CEP組),分彆于術後24 h後予營養支持.觀察在治療過程中兩組患者術後併髮癥的髮生率、胃腸功能恢複時間、術後平均住院天數、免疫指標及營養評定等各項指標進行對比分析.結果 兩組患者術後併髮癥的髮生率(TPN組9％、CEP組3％)；胃腸道功能恢複時間TPN組(69.75±9.49)h、CEP組(48.54±8.46)h；平均住院時間TPN組(15.18±2.21)d、CEP組(12.89±2.23)d,CEP組明顯低于TPN組(P＜0.05)；兩組術後血漿總蛋白(TP)、血漿白蛋白(ALB)、血紅蛋白(HGB)和體質量(BW)在營養支持後均有所下降(P＜0.05),TPN組淋巴細胞計數(LY)減少(P＜0.05),CEP組LY差異無統計學意義(P＞0.05)；兩組營養及免疫指標組間差異無統計學意義(P＞0.05).結論 胃癌術後早期腸內營養聯閤腸外營養,在改善機體營養狀況方麵與全腸外營養相似,在加快免疫狀態改善,降低併髮癥髮生率方麵要優于全腸外營養.
목적 탐토위암술후환자조기불동영양지지방법、료효관찰급응용개치.방법 장100례위암근치술후환자수궤분위량조,분별진행전장외영양지지(TPN조)화장내연합장외영양지지(CEP조),분별우술후24 h후여영양지지.관찰재치료과정중량조환자술후병발증적발생솔、위장공능회복시간、술후평균주원천수、면역지표급영양평정등각항지표진행대비분석.결과 량조환자술후병발증적발생솔(TPN조9％、CEP조3％)；위장도공능회복시간TPN조(69.75±9.49)h、CEP조(48.54±8.46)h；평균주원시간TPN조(15.18±2.21)d、CEP조(12.89±2.23)d,CEP조명현저우TPN조(P＜0.05)；량조술후혈장총단백(TP)、혈장백단백(ALB)、혈홍단백(HGB)화체질량(BW)재영양지지후균유소하강(P＜0.05),TPN조림파세포계수(LY)감소(P＜0.05),CEP조LY차이무통계학의의(P＞0.05)；량조영양급면역지표조간차이무통계학의의(P＞0.05).결론 위암술후조기장내영양연합장외영양,재개선궤체영양상황방면여전장외영양상사,재가쾌면역상태개선,강저병발증발생솔방면요우우전장외영양.
Objective To investigate the effectiveness and applied value of different nutritional support methods in the early stage after radical resection of gastric cancer.Methods 100 patients with gastric cancer subject to radical resection were randomly divided into two groups:total parenteral nutrition (TPN) group,and enteral nutrition (EN) combined with TPN (EN + TPN) group.Nutritional support was given 24 h after operation.The incidence of postoperative complications,gastrointestinal function recovery time,postoperative hospitalization days,and the indexes of immune function and nutrition assessment were analyzed.Results The incidence of postoperative complications in TPN group and EN + TPN group was 9％ and 3％,gastrointestinal function recovery time was (69.75 ± 9.49) h and (48.54 ±8.46) h,and the average hospital stay was (15.18 ± 2.21) days and (12.89 ± 2.23) days respectively (P ＜0.05 for all).In both two two groups after operation,the serum total protein (TP),plasma albumin (ALB),hemoglobin (HGB) and body weight (BW) were decreased after nutritional support to some extent (P ＜ 0.05).Lymphocyte count (LY) in TPN group was decreased (P ＜ 0.05),and no significant change was found in LY in EN + TPN group (P ＞ 0.05).There was no statistically significant difference in the indexes of immune function and nutrition assessment between two groups (P ＞ 0.05).Conclusion The effects of early EN combined with TPN improving the nutritional status of body after radical resection of gastric cancer were similar to those of PTN.Early EN combined with TPN could quickly improve the immune state and significant reduce the incidence of complications in comparison to TPN used alone.
