CAJ | 학술논문

目的探讨神经生长因子(NGF)在肘关节恐怖三联征患者经微创前内侧双开窗入路治疗后的表达及其与患者预后的关系.方法采用酶联免疫吸附试验(ELASA)法检测60例肘关节恐怖三联征患者血清中NGF的表达水平,评估NGF表达与患者术后愈合时间、功能恢复及并发症的关系.结果 NGF高表达患者术后骨折愈合时间[(10.1±3.1)周]明显短于低表达患者[(21.2±9.6)周,P＜0.05].同时,高表达NGF患者功能恢复情况明显优于低表达患者(P＜0.05).此外,高表达NGF患者术后并发症的发生率约为2.3％,明显低于低表达患者(23.5％),两者差异有统计学意义(P＜0.05).结论神经因子的表达与微创内侧双开窗入路治疗的肘关节恐怖三联征患者的预后明显相关,其高表达可有效缩短患者愈合的时间,促进功能恢复及降低并发症的发生.
목적 탐토신경생장인자(NGF)재주관절공포삼련정환자경미창전내측쌍개창입로치료후적표체급기여환자예후적관계.방법 채용매련면역흡부시험(ELASA)법검측60례주관절공포삼련정환자혈청중NGF적표체수평,평고NGF표체여환자술후유합시간、공능회복급병발증적관계.결과 NGF고표체환자술후골절유합시간[(10.1±3.1)주]명현단우저표체환자[(21.2±9.6)주,P＜0.05].동시,고표체NGF환자공능회복정황명현우우저표체환자(P＜0.05).차외,고표체NGF환자술후병발증적발생솔약위2.3％,명현저우저표체환자(23.5％),량자차이유통계학의의(P＜0.05).결론 신경인자적표체여미창내측쌍개창입로치료적주관절공포삼련정환자적예후명현상관,기고표체가유효축단환자유합적시간,촉진공능회복급강저병발증적발생.
Objective To investigate the expression of nerve growth factor (NGF) in patients with terrible triad of the elbow after treatment with minimally invasive double window surgery and ite correlation with prognosis.Methods The expression of serum NGF in 60 patients with terrible triad of the elbow was detected by using enzyme-linked immunosorbent assay (ELASA),and its relationship with function recovery,healing time and complications was analyzed.Results Healing time in patients with high NGF expression was significantly shorter than that in those with low NGF expression (P ＜ 0.05).The function recovery in patients with high NGF expression was better than that in those with low NGF expression (P ＜ 0.05).Additionally,the incidence of postoperative complications in patients with high NGF expression was 2.3％,significantly lower than that in those with low NGF expression (23.5％,P ＜ 0.05).Conclusion NGF expression is associated with the prognosis of patients with terrible triad of the elbow after treatment with minimally invasive double window surgery and its high expression can effectively shorten the healing time,promote the functional recovery,and reduce complications.