CAJ | 학술논문

目的观察普通外科感染、非感染性全身炎症反应综合征(SIRS)及手术病例血清降钙素原(PCT)的变化,探讨降钙素原在判断普通外科感染病例中的价值.方法 266例普通外科患者,分为3组:手术组、非感染性SIRS组、感染组.动态观察(入院日、治疗后第1、3、7天)血清PCT水平,比较3组PCT的动态变化和3组间的差异.结果感染组入院日的PCT水平[(6.65±4.23) μg/L]明显升高,感染控制后恢复[(0.43 ±0.47) μg/L],非感染性SIRS组轻度升高[(0.76±0.49) μg/L],手术组入院时正常[(0.14±0.31)μg/L]仅在术后轻度升高[(1.87±0.45)μg/L],3d后恢复[(0.20 ±0.14)μg/L].入院日PCT 3组比较差异有统计学意义(P＜0.01).结论 PCT可以作为判断普通外科感染性SIRS和非感染性SIRS的敏感且特异的指标.
목적 관찰보통외과감염、비감염성전신염증반응종합정(SIRS)급수술병례혈청강개소원(PCT)적변화,탐토강개소원재판단보통외과감염병례중적개치.방법 266례보통외과환자,분위3조:수술조、비감염성SIRS조、감염조.동태관찰(입원일、치료후제1、3、7천)혈청PCT수평,비교3조PCT적동태변화화3조간적차이.결과 감염조입원일적PCT수평[(6.65±4.23) μg/L]명현승고,감염공제후회복[(0.43 ±0.47) μg/L],비감염성SIRS조경도승고[(0.76±0.49) μg/L],수술조입원시정상[(0.14±0.31)μg/L]부재술후경도승고[(1.87±0.45)μg/L],3d후회복[(0.20 ±0.14)μg/L].입원일PCT 3조비교차이유통계학의의(P＜0.01).결론 PCT가이작위판단보통외과감염성SIRS화비감염성SIRS적민감차특이적지표.
Objective To investigate the variation of procalcitonin (PCT) level and the significance of procalcitonin testing in general surgery patients with bacterial infection systemic inflammatory response syndrome (SIRS) or intraoperative SIRS.Methods 266 hospitalized patients in our general surgery ward were selected,and divided into three groups:SIRS group,bacterial infectious SIRS group and operation group.The levels of serum PCT in all patients were determined on the day of admission,and 1 st day,3rd day,and 7th day after treatment.The changes of PCT level in each group and the differences among the three groups were compared.Results Serum PCT level limited increased in SIRS group [(0.76 ± 0.49) μg/L],which significant increased in bacterial infectious SIRS group [(6.65 ±4.23) μg/L] at the day be admitted to hospital and recovered after infection controlled [(0.43 ±0.47) μg/L].In operation group serum PCT level transient increased from (0.14 ± 0.31) μg/L before operation to (1.87 ± 0.45) μg/L at the 1st day after operation and fell down to (0.20 ±0.14) μg/L at 3rd day after operation.A statistically significant was observed between three groups at the day be admitted to hospital (P ＜ 0.01).Conclusion Serum PCT level can be used as an indicator for differential diagnosis of bacterial infection SIRS and SIRS.