中华肾脏病杂志
中華腎髒病雜誌
중화신장병잡지
2014年
8期
580-585
,共6页
顾玥%黄承国%阎磊%陈晖%刘冰%邵凤民
顧玥%黃承國%閻磊%陳暉%劉冰%邵鳳民
고모%황승국%염뢰%진휘%류빙%소봉민
腹膜透析%营养不良%外周血管疾病%踝臂指数
腹膜透析%營養不良%外週血管疾病%踝臂指數
복막투석%영양불량%외주혈관질병%과비지수
Peritoneal dialysis%Malnutrition%Peripheral vascular disease%Ankle brachial index
目的 探讨持续性非卧床腹膜透析(CAPD)患者营养与外周动脉疾病(PAD)的关系.方法 应用踝臂指数(ABI)测定仪测定CAPD患者ABI,根据ABI将患者分为PAD组(ABI＜ 0.9)和非PAD组(ABI≥0.9).收集患者临床资料,检测相关血生化指标,评估营养状况相关指标:血白蛋白、握力(HGS)、主观综合性营养评估(SGA).用logistic回归方法分析PAD与营养及其他因素间的关系.结果 入选患者102例,PAD的发生率为23.53％ (24/102).营养不良组(SGA评估)ABI显著低于营养良好组[(0.72±0.21)比(1.04±0.14),P＜0.01].与非PAD组相比,PAD组血白蛋白、HGS、舒张压、血肌酐、血尿素氮显著降低(均P＜0.05),年龄、营养不良(SGA评估)发生率、糖尿病史比例、心血管病史比例显著增加(均P＜0.01).多因素logistic回归分析结果显示血白蛋白(OR=0.762,95％CI:0.611～0.948,P=0.015)、HGS(OR=0.988,95％CI:0.979 ～ 0.997,P=0.013)是CAPD患者发生PAD的独立保护因素;营养不良(SGA评估)[OR=21.101,95％CI:5.008～88.901,P＜0.01]是CAPD患者发生PAD的独立危险因素.结论 本中心CAPD患者PAD的发生率为23.53％.营养是CAPD患者发生PAD的相关因素.
目的 探討持續性非臥床腹膜透析(CAPD)患者營養與外週動脈疾病(PAD)的關繫.方法 應用踝臂指數(ABI)測定儀測定CAPD患者ABI,根據ABI將患者分為PAD組(ABI＜ 0.9)和非PAD組(ABI≥0.9).收集患者臨床資料,檢測相關血生化指標,評估營養狀況相關指標:血白蛋白、握力(HGS)、主觀綜閤性營養評估(SGA).用logistic迴歸方法分析PAD與營養及其他因素間的關繫.結果 入選患者102例,PAD的髮生率為23.53％ (24/102).營養不良組(SGA評估)ABI顯著低于營養良好組[(0.72±0.21)比(1.04±0.14),P＜0.01].與非PAD組相比,PAD組血白蛋白、HGS、舒張壓、血肌酐、血尿素氮顯著降低(均P＜0.05),年齡、營養不良(SGA評估)髮生率、糖尿病史比例、心血管病史比例顯著增加(均P＜0.01).多因素logistic迴歸分析結果顯示血白蛋白(OR=0.762,95％CI:0.611～0.948,P=0.015)、HGS(OR=0.988,95％CI:0.979 ～ 0.997,P=0.013)是CAPD患者髮生PAD的獨立保護因素;營養不良(SGA評估)[OR=21.101,95％CI:5.008～88.901,P＜0.01]是CAPD患者髮生PAD的獨立危險因素.結論 本中心CAPD患者PAD的髮生率為23.53％.營養是CAPD患者髮生PAD的相關因素.
목적 탐토지속성비와상복막투석(CAPD)환자영양여외주동맥질병(PAD)적관계.방법 응용과비지수(ABI)측정의측정CAPD환자ABI,근거ABI장환자분위PAD조(ABI＜ 0.9)화비PAD조(ABI≥0.9).수집환자림상자료,검측상관혈생화지표,평고영양상황상관지표:혈백단백、악력(HGS)、주관종합성영양평고(SGA).용logistic회귀방법분석PAD여영양급기타인소간적관계.결과 입선환자102례,PAD적발생솔위23.53％ (24/102).영양불량조(SGA평고)ABI현저저우영양량호조[(0.72±0.21)비(1.04±0.14),P＜0.01].여비PAD조상비,PAD조혈백단백、HGS、서장압、혈기항、혈뇨소담현저강저(균P＜0.05),년령、영양불량(SGA평고)발생솔、당뇨병사비례、심혈관병사비례현저증가(균P＜0.01).다인소logistic회귀분석결과현시혈백단백(OR=0.762,95％CI:0.611～0.948,P=0.015)、HGS(OR=0.988,95％CI:0.979 ～ 0.997,P=0.013)시CAPD환자발생PAD적독립보호인소;영양불량(SGA평고)[OR=21.101,95％CI:5.008～88.901,P＜0.01]시CAPD환자발생PAD적독립위험인소.결론 본중심CAPD환자PAD적발생솔위23.53％.영양시CAPD환자발생PAD적상관인소.
Objective To investigate the association between nutrition and peripheral artery disease (PAD) in continuous ambulatory peritoneal dialysis (CAPD) patients.Methods One hundred and two stable CAPD patients from a single center were enrolled in this cross-sectional study.Automatic ankle-brachial index (ABI) measuring system was applied to examine ABI.Patients were divided into PAD group (ABI ＜ 0.9) and non-PAD group (ABI≥0.9).Clinical data were collected.Biochemical parameters were detected.Nutritional status was evaluated by serum albumin,handgrip strength (HGS) and subjective global assessment (SGA).Logistic regression analysis was performed to estimate the association of PAD with each nutritional marker as well as other potential risk factors.Results The incidence of PAD was 23.53％ (24/102).ABI was significantly lower in patients with malnutrition as compared to those without malnutrition [(0.72 ± 0.21) vs (1.04 ± 0.14),P＜0.01].Compared with non-PAD patients,serum albumin (P ＜ 0.01),HGS (P ＜ 0.01),diastolic blood pressure (P ＜ 0.05),serum creatine (P ＜ 0.05)、blood urine nitrogen (P ＜ 0.01) were significantly decreased,but age (P ＜ 0.01),the incidence of malnutrition [SGA,P ＜ 0.01],diabetic status (P ＜ 0.01),cardiovascular disease history (P ＜ 0.01) were significantly increased in PAD patients.Logistic regression analysis showed that serum albumin (OR=0.762,95％ CI:0.611-0.948,P=0.015),HGS (OR=0.988,95％ CI:0.979-0.997,P=0.013) were independent protective factors for PAD,malnutrition [(SGA),OR=21.101,95％ CI:5.008-88.901,P＜0.01] was independent risk factor for PAD in CAPD patients.Conclusions The PAD incidence of CAPD patients in our center is 23.53％.Nutrition is independent factor associated with PAD in CAPD patients.
