中华糖尿病杂志
中華糖尿病雜誌
중화당뇨병잡지
CHINES JOURNAL OF DLABETES MELLITUS
2013年
1期
29-33
,共5页
杨光燃%袁申元%傅汉菁%万钢%朱良湘%袁明霞%潘素芳%卜祥雷%张建东%杜雪平
楊光燃%袁申元%傅漢菁%萬鋼%硃良湘%袁明霞%潘素芳%蔔祥雷%張建東%杜雪平
양광연%원신원%부한정%만강%주량상%원명하%반소방%복상뢰%장건동%두설평
糖尿病,2型%颈围%血脂异常%社区
糖尿病,2型%頸圍%血脂異常%社區
당뇨병,2형%경위%혈지이상%사구
Diabetes,type 2%Neck circumference%Dyslipidemia%Community
目的 了解2型糖尿病患者颈围与血脂谱问的关系.方法 选择2008年8月至2009年7月北京三甲医院与15个城区社区联合开展糖尿病纵向管理项目基线数据库中2410例2型糖尿病患者.全体参与医师经过专门培训,按统一要求调查并填写调查表,同时对患者进行体格检查及相关的实验室检查,血脂异常的诊断根据2007年中国成人血脂异常防治指南.结果 (1)2410例中男986例,女1424例.平均颈围为(36 ±4)cm.总胆固醇为(5.2 ±1.1)mmol/L；甘油三酯为(1.8±1.2) mmol/L；高密度脂蛋白胆固醇(HDL-C)为(1.3±0.4)mmol/L；低密度脂蛋白胆固醇(LDL-C)为(3.0±0.9) mmol/L；(2)男性、女性的颈围均与甘油三酯呈正相关(男性r=0.093,女性r=0.077,均P＜0.01),与HDL-C呈负相关(男性r=-0.144,女性r=-0.062,均P＜0.05)；(3)预测高甘油三酯血症最佳的颈围切点:男性为37 cm,女性为35 cn；预测HDL-C降低的颈围切点男性为40 cm,女性为35 cm；(4)预测高胆固醇血症受试者操作特征(ROC)曲线下面积男性组为0.511,女性组为0.480(P ＞0.05)；预测LDL-C升高ROC曲线下面积男性为0.527；女性为0.519(P＞0.05).结论2型糖尿病患者的颈围与血脂密切相关,尤其是甘油三酯和HDL-C;颈围可能做为筛查/评价2型糖尿病患者血脂异常的指标之一.
目的 瞭解2型糖尿病患者頸圍與血脂譜問的關繫.方法 選擇2008年8月至2009年7月北京三甲醫院與15箇城區社區聯閤開展糖尿病縱嚮管理項目基線數據庫中2410例2型糖尿病患者.全體參與醫師經過專門培訓,按統一要求調查併填寫調查錶,同時對患者進行體格檢查及相關的實驗室檢查,血脂異常的診斷根據2007年中國成人血脂異常防治指南.結果 (1)2410例中男986例,女1424例.平均頸圍為(36 ±4)cm.總膽固醇為(5.2 ±1.1)mmol/L；甘油三酯為(1.8±1.2) mmol/L；高密度脂蛋白膽固醇(HDL-C)為(1.3±0.4)mmol/L；低密度脂蛋白膽固醇(LDL-C)為(3.0±0.9) mmol/L；(2)男性、女性的頸圍均與甘油三酯呈正相關(男性r=0.093,女性r=0.077,均P＜0.01),與HDL-C呈負相關(男性r=-0.144,女性r=-0.062,均P＜0.05)；(3)預測高甘油三酯血癥最佳的頸圍切點:男性為37 cm,女性為35 cn；預測HDL-C降低的頸圍切點男性為40 cm,女性為35 cm；(4)預測高膽固醇血癥受試者操作特徵(ROC)麯線下麵積男性組為0.511,女性組為0.480(P ＞0.05)；預測LDL-C升高ROC麯線下麵積男性為0.527；女性為0.519(P＞0.05).結論2型糖尿病患者的頸圍與血脂密切相關,尤其是甘油三酯和HDL-C;頸圍可能做為篩查/評價2型糖尿病患者血脂異常的指標之一.
목적 료해2형당뇨병환자경위여혈지보문적관계.방법 선택2008년8월지2009년7월북경삼갑의원여15개성구사구연합개전당뇨병종향관리항목기선수거고중2410례2형당뇨병환자.전체삼여의사경과전문배훈,안통일요구조사병전사조사표,동시대환자진행체격검사급상관적실험실검사,혈지이상적진단근거2007년중국성인혈지이상방치지남.결과 (1)2410례중남986례,녀1424례.평균경위위(36 ±4)cm.총담고순위(5.2 ±1.1)mmol/L；감유삼지위(1.8±1.2) mmol/L；고밀도지단백담고순(HDL-C)위(1.3±0.4)mmol/L；저밀도지단백담고순(LDL-C)위(3.0±0.9) mmol/L；(2)남성、녀성적경위균여감유삼지정정상관(남성r=0.093,녀성r=0.077,균P＜0.01),여HDL-C정부상관(남성r=-0.144,녀성r=-0.062,균P＜0.05)；(3)예측고감유삼지혈증최가적경위절점:남성위37 cm,녀성위35 cn；예측HDL-C강저적경위절점남성위40 cm,녀성위35 cm；(4)예측고담고순혈증수시자조작특정(ROC)곡선하면적남성조위0.511,녀성조위0.480(P ＞0.05)；예측LDL-C승고ROC곡선하면적남성위0.527；녀성위0.519(P＞0.05).결론2형당뇨병환자적경위여혈지밀절상관,우기시감유삼지화HDL-C;경위가능주위사사/평개2형당뇨병환자혈지이상적지표지일.
Objective To investigate the association between neck circumference and lipid profile in Chinese individuals with type 2 diabetes.Methods Total of 2410 subjects with type 2 diabetes (age 20-80 yrs) were recruited from 15 community health centers in Beijing using a multi-stage random sampling approach.Dyslipidemia was diagnosed according to 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults.Results (1) The study sample consisted of 986 men and 1424 women with a mean neck circumferenee of (36 ± 4) cm.Mean total cholesterol,triglyceride,high-density lipoprotein cholesteroland low-density lipoprotein cholesterol was (5.2 ± 1.1) mmol/L,(1.8 ± 1.2) mmol/L,(1.3 ± 0.4) mmol/L and (3.0 ± 0.9) mmol/L,respectively.(2) Neck circumference correlated positively with triglyceride (men (r =0.093),women(r =0.077),P ＜ 0.01).Neck circumference correlated negatively with high-density lipoprotein cholesterol (men (r =-0.144),women (r =-0.062),P ＜ 0.05).(3) Receiver operating characteristic analysis showed that a neck circumference of 37 cm for men and 35 cm for women was the best cutoff point for determining hypertriglyceridemia subjects.A neck circumference of 40 cm for men and 35 cm for women was the best cutoff point to determine subjects with decreased high-density lipoprotein cholesterol.(4) Receiver operating characteristic analysis showed that the area under the curve for neck circumference and hypercholeslerolemia was 0.511 for men and 0.480 for women (P ＞ 0.05).Receiver operating characteristic analysis showed that the area under the curve for neck circumference and low-density lipoprotein cholesterol was 0.527 for men and 0.519 for women (P ＞0.05).Conclusion In the present study,neck circumference is related with lipid profile in Chinese individuals with type 2 diabetes,especially triglyceride and high-density lipoprotein cholesterol.Neck circumference might be used in a clinical setting as an indicator for screening or evaluating dyslipidemia in type 2 diabetic subjects.
