中华糖尿病杂志
中華糖尿病雜誌
중화당뇨병잡지
CHINES JOURNAL OF DLABETES MELLITUS
2013年
5期
275-278
,共4页
邢晓欢%严晋华%杨黛稚%李津%邓洪容%章燕%姚斌%翁建平
邢曉歡%嚴晉華%楊黛稚%李津%鄧洪容%章燕%姚斌%翁建平
형효환%엄진화%양대치%리진%산홍용%장연%요빈%옹건평
糖尿病,1型%血红蛋白A,糖基化%血糖自我监测%疾病管理
糖尿病,1型%血紅蛋白A,糖基化%血糖自我鑑測%疾病管理
당뇨병,1형%혈홍단백A,당기화%혈당자아감측%질병관리
Diabetes mellitus,type 1%Hemoglobin A,glycosylated%Blood glucose self-monitoring%Disease management
目的 探讨综合管理对1型糖尿病(T1DM)血糖控制的影响.方法 纳入2010年8月6日至2013年1月1日在中山大学附属第三医院就诊随访的T1DM患者,实施综合管理,包括3个月1次的规律随访、糖尿病教育、治疗方案调整及免费的糖化血红蛋白(HbA1c)检测等.根据HbA1c是否达到相应年龄段的血糖控制目标将患者分为达标组和未达标组.采用logistic回归模型分析HbA1c达标与各因素的相关性.结果 共纳入144例T1DM患者,男64例,女80例,中位年龄29.0岁(四分位间距22.0,38.0,下同),糖尿病病程4.5年(2.8,9.0),体质指数(BMI) 19.8 kg/m2(18.9,22.0),干预前HbA1c 8.2％ (6.7％,9.8％),41例(28.5％) HbA1c达标.完成3、6、9、12个月随访的患者分别为97、50、44、36例,HbA1c达标率分别为50.5％、80％、77％、63.9％.随访3、6、9、12个月HbA1c分别为7.2％(6.4％,8.3％)、7.2％(6.6％,7.9％)、7.0％(6.4％,7.7％)、7.0％(6.5％,8.0％),与干预前比较差异均有统计学意义(均P ＜0.05).Logistic回归分析显示年龄较大、BMI较小、自我血糖监测(SMBG)频率较高的和病程较短的患者血糖控制较好.结论 综合管理有助于T1 DM的血糖控制,增加自我血糖监测频率对血糖控制有利.
目的 探討綜閤管理對1型糖尿病(T1DM)血糖控製的影響.方法 納入2010年8月6日至2013年1月1日在中山大學附屬第三醫院就診隨訪的T1DM患者,實施綜閤管理,包括3箇月1次的規律隨訪、糖尿病教育、治療方案調整及免費的糖化血紅蛋白(HbA1c)檢測等.根據HbA1c是否達到相應年齡段的血糖控製目標將患者分為達標組和未達標組.採用logistic迴歸模型分析HbA1c達標與各因素的相關性.結果 共納入144例T1DM患者,男64例,女80例,中位年齡29.0歲(四分位間距22.0,38.0,下同),糖尿病病程4.5年(2.8,9.0),體質指數(BMI) 19.8 kg/m2(18.9,22.0),榦預前HbA1c 8.2％ (6.7％,9.8％),41例(28.5％) HbA1c達標.完成3、6、9、12箇月隨訪的患者分彆為97、50、44、36例,HbA1c達標率分彆為50.5％、80％、77％、63.9％.隨訪3、6、9、12箇月HbA1c分彆為7.2％(6.4％,8.3％)、7.2％(6.6％,7.9％)、7.0％(6.4％,7.7％)、7.0％(6.5％,8.0％),與榦預前比較差異均有統計學意義(均P ＜0.05).Logistic迴歸分析顯示年齡較大、BMI較小、自我血糖鑑測(SMBG)頻率較高的和病程較短的患者血糖控製較好.結論 綜閤管理有助于T1 DM的血糖控製,增加自我血糖鑑測頻率對血糖控製有利.
목적 탐토종합관리대1형당뇨병(T1DM)혈당공제적영향.방법 납입2010년8월6일지2013년1월1일재중산대학부속제삼의원취진수방적T1DM환자,실시종합관리,포괄3개월1차적규률수방、당뇨병교육、치료방안조정급면비적당화혈홍단백(HbA1c)검측등.근거HbA1c시부체도상응년령단적혈당공제목표장환자분위체표조화미체표조.채용logistic회귀모형분석HbA1c체표여각인소적상관성.결과 공납입144례T1DM환자,남64례,녀80례,중위년령29.0세(사분위간거22.0,38.0,하동),당뇨병병정4.5년(2.8,9.0),체질지수(BMI) 19.8 kg/m2(18.9,22.0),간예전HbA1c 8.2％ (6.7％,9.8％),41례(28.5％) HbA1c체표.완성3、6、9、12개월수방적환자분별위97、50、44、36례,HbA1c체표솔분별위50.5％、80％、77％、63.9％.수방3、6、9、12개월HbA1c분별위7.2％(6.4％,8.3％)、7.2％(6.6％,7.9％)、7.0％(6.4％,7.7％)、7.0％(6.5％,8.0％),여간예전비교차이균유통계학의의(균P ＜0.05).Logistic회귀분석현시년령교대、BMI교소、자아혈당감측(SMBG)빈솔교고적화병정교단적환자혈당공제교호.결론 종합관리유조우T1 DM적혈당공제,증가자아혈당감측빈솔대혈당공제유리.
Objective To investigate the effect of disease-management programs on glycemic control in type 1 diabetic (T1DM) patients.Methods T1DM patients registered in the Third Affiliated Hospital of Sun Yat-sen University from August 6,2010 to January 1,2013 were enrolled and disease-management programs were implied in those patients,including scheduled follow-up every 3 months,diabetic education,treatment plan adjustment and free glycated hemoglobin A1c (HbA1c) test in each visit.The patients were divided into two groups according to the HbA1 c level:those whose HbA1 c reached the control standard and those not.Multivariate logistic regression analysis was used to investigate the correlative factors for control effect of HbA1c.Results Total of 144 T1DM patients were enrolled,among them 64 were male,80 were female,the patients aged 29.0 years (interquartile range:22.0,38.0,same below) with a T1DM duration of 4.5 years (2.8,9.0) and a body mass index (BMI) of 19.8 kg/m2 (18.9,22.0).The HbA1c at baseline was 8.2％ (6.7％,9.8％) and 41 patients (28.5％) achieved the age-specific HbAlc targets after the therapy.The number of patients completed the 3-,6-,9-and 12-month follow-up was 97,50,44and 36,respectively.And of them,50.5％,80％,77％,63.9％ reached the age-specific glycemic control goals at the 3-,6-,9-and 12-month visit,respectively.HbA1c fell from 8.2 (6.7％,9.8％) at baseline to7.2％ (6.4％,8.3％) at3-month,7.2％ (6.6％,7.9％) at6-month,7.0％ (6.4％,7.7％) at9-month and 7.0％ (6.5％,8.0％) at 12-month (all P ＜ 0.05 compared with baseline).Binary logistic regression analysis showed that patients who were older,with lower BMI,more frequent self-monitoring of blood glucose(SMBG) and shorter diabetic duration had better glycemic control.Conclusions Diseasemanagement programs has a favorable effect on glycemic control in T1DM patients.Higher frequency of SMBG is beneficial for glycemic improvement.
