CAJ | 학술논문

选取2010年6月至2011年2月郑州市6个社区40岁以上女性常住居民6 785名,根据血糖水平分为血糖正常组(NC组)、血糖调节受损(IGR)组与糖尿病组(DM组),比较3组人群在子女数量、年龄、血脂、血压、腰围、臀围、体质指数(BMI)以及饮酒、吸烟、哺乳等方面的差异.以logistic回归分析糖尿病发生风险.结果显示,NC组3 170例、IGR组2 035例,DM组1 580例.NC组子女数量为4(0,8)个,IGR组子女数量为5(0,10)个,DM组子女数量为5(0,10)个,差异有统计学意义(F=100.95,P ＜0.05).经logistic回归显示,子女数量与IGR、糖尿病的发生风险存在正相关性,随着子女数量的增加,血糖代谢恶化的风险升高(OR:1.115,95％ CI:0.063～0.156,P＜0.05).结果表明生育子女数量的多少与中老年女性发生IGR和糖尿病的风险存在相关性,并且生育子女数增多可能是中老年女性发生IGR和DM的危险因素之一.
선취2010년6월지2011년2월정주시6개사구40세이상녀성상주거민6 785명,근거혈당수평분위혈당정상조(NC조)、혈당조절수손(IGR)조여당뇨병조(DM조),비교3조인군재자녀수량、년령、혈지、혈압、요위、둔위、체질지수(BMI)이급음주、흡연、포유등방면적차이.이logistic회귀분석당뇨병발생풍험.결과현시,NC조3 170례、IGR조2 035례,DM조1 580례.NC조자녀수량위4(0,8)개,IGR조자녀수량위5(0,10)개,DM조자녀수량위5(0,10)개,차이유통계학의의(F=100.95,P ＜0.05).경logistic회귀현시,자녀수량여IGR、당뇨병적발생풍험존재정상관성,수착자녀수량적증가,혈당대사악화적풍험승고(OR:1.115,95％ CI:0.063～0.156,P＜0.05).결과표명생육자녀수량적다소여중노년녀성발생IGR화당뇨병적풍험존재상관성,병차생육자녀수증다가능시중노년녀성발생IGR화DM적위험인소지일.
A total of 6 785 female participants were collected,containing 3 170 orthoglycemic women(NC group),2 035 impaired glucose regulation women(IGR group) and 1 580 diabetic women (DM group).The clinical data were investigated,including the number of children,age,serum lipids,blood pressure,waist and hip circumference,smoking,drinking,and so on.The association between increasing number of children and glucose metabolic status was evaluated by stepwise logistic regression.Among the NC group (n =3 170),IGR group (n =2 035) and DM group (n =1 580),there was significant difference in the number of children that NC group has least children with a mean of 4 (0,8),and DM group has most children with a mean of 5 (0,10).In a full model,after controlling other factors,the number of children had a significant positive influence on the diabetes risk of middle-aged women (OR: 1.115,95％ CI: 0.063-0.156,P ＜0.05).The number of children was associated with IGR and DM in middle-aged women,and this relationship seemed to suggest grand multiparity may be one risk factor of IGR and DM in middle-aged women.