CAJ | 학술논문

目的观察低高密度脂蛋白胆固醇(HDL-C)血症有氧训练的效果.方法选取低HDL-C血症患者60例,根据训练强度的不同采用随机数字表法分为高、中、低强度3个训练组,每组患者20例.参照3组患者在症状限制性心电运动试验结果中所取得的最高心率制订运动强度,高强度训练组采用90％最高心率为靶心率的运动强度,中强度训练组采取70％最高心率为靶心率的运动强度,低强度训练组采取50％最高心率为靶心率的运动强度；3组患者均采用医用跑台(可随时监测心率)跑步的运动方式进行训练;3组达靶心率的运动时间均为每次20 min；每组均隔天运动1次,疗程为2个月.记录3组患者训练前和训练2个月后(训练后)HDL-C值,并对其水平变化及3组患者训练后低HDL-C达正常值的例数进行比较.结果高强度、中强度和低强度训练组HDL-C水平分别由训练前的(0.81±0.22) mmol/L、(0.82±0.20) mmol/L和(0.79±0.25) mmol/L提高到训练后的(1.04±0.33) mmol/L、(1.03±0.37) mmol/L和(0.82±0.27) mmol/L;训练后,高强度和中强度训练组的HDL-C水平均显著高于组内训练前和低强度训练组训练后,差异均有统计学意义(P＜0.05),但高强度训练组与中强度训练组间HDL-C水平比较,差异无统计学意义(P＞0.05).训练后HDL-C达正常值(HDL-C≥1.04 mmol/L)例数分别为高强度训练组15例(15/20),中强度训练组13例(13/20),低强度训练组l例(1/20),且高、中强度训练组与低强度训练组比较,差异均有统计学意义(P＜0.01).结论中、高强度有氧运动均能有效地改善低HDL-C血症患者的HDL-C水平,且中强度训练与高强度训练对其HDL-C水平和HDL-C达正常值例数的影响,差异无统计学意义(P＞0.05),建议临床采用中等强度有氧运动治疗低HDL-C血症.
목적 관찰저고밀도지단백담고순(HDL-C)혈증유양훈련적효과.방법 선취저HDL-C혈증환자60례,근거훈련강도적불동채용수궤수자표법분위고、중、저강도3개훈련조,매조환자20례.삼조3조환자재증상한제성심전운동시험결과중소취득적최고심솔제정운동강도,고강도훈련조채용90％최고심솔위파심솔적운동강도,중강도훈련조채취70％최고심솔위파심솔적운동강도,저강도훈련조채취50％최고심솔위파심솔적운동강도；3조환자균채용의용포태(가수시감측심솔)포보적운동방식진행훈련;3조체파심솔적운동시간균위매차20 min；매조균격천운동1차,료정위2개월.기록3조환자훈련전화훈련2개월후(훈련후)HDL-C치,병대기수평변화급3조환자훈련후저HDL-C체정상치적례수진행비교.결과 고강도、중강도화저강도훈련조HDL-C수평분별유훈련전적(0.81±0.22) mmol/L、(0.82±0.20) mmol/L화(0.79±0.25) mmol/L제고도훈련후적(1.04±0.33) mmol/L、(1.03±0.37) mmol/L화(0.82±0.27) mmol/L;훈련후,고강도화중강도훈련조적HDL-C수평균현저고우조내훈련전화저강도훈련조훈련후,차이균유통계학의의(P＜0.05),단고강도훈련조여중강도훈련조간HDL-C수평비교,차이무통계학의의(P＞0.05).훈련후HDL-C체정상치(HDL-C≥1.04 mmol/L)례수분별위고강도훈련조15례(15/20),중강도훈련조13례(13/20),저강도훈련조l례(1/20),차고、중강도훈련조여저강도훈련조비교,차이균유통계학의의(P＜0.01).결론 중、고강도유양운동균능유효지개선저HDL-C혈증환자적HDL-C수평,차중강도훈련여고강도훈련대기HDL-C수평화HDL-C체정상치례수적영향,차이무통계학의의(P＞0.05),건의림상채용중등강도유양운동치료저HDL-C혈증.
Objective To observe the effects of aerobic exercise on low-and high-density lipoprotein cholesterol,and to investigate the relationship between exercise intensities and high-density lipoprotein cholesterol (HDL-C) changes.Methods Sixty patients with low HDL-C were randomly allocated into a high intensity exercise group,a moderate intensity group or a low intensity group with 20 in each group.According to each patient's maximal heart rate in a restrictive electrocardiogram exercise test,the different aerobic exercise intensities were formulated as follows.The target heart rate of the high-intensity training group was 90％ of each subject's maximum heart rate; in the moderate-intensity group it was 70％ ; in the low-intensity group it was 50％.All 3 groups jogged on a medical treadmill for 20 minutes every other day with their heart rates monitored at all times.They maintained the target heart rate for 20 minutes.The experiment lasted 2 months.Results In the high intensity group HDL-C increased from 0.81 ± 0.22 to 1.04 ± 0.33 mmol/L after training; in the moderate intensity group it increased from 0.82±0.20 to 1.03 ±0.37 mmol/L; in the low intensity group it increased from 0.79 ±0.25 to 0.82 ± 0.27 mmol/L.That increase in the low intensity group was not statistically significant.After high intensity or moderate intensity training the HDL-C increases were statistically significant,but the difference between the groups was not.After training,in 15 cases among the high intensity group,13 cases from moderate intensity group and in 1 case from the low intensity group the HDL-C level achieved a normal value (≥ 1.04 mmol/L).Comparing the high intensity group to the low intensity group or the moderate intensity group to the low intensity group,there were significant differences in the number of patients who achieved normal HDL-C readings,but there was no significant difference between high intensity group and the moderate intensity group.Conclusion Low intensity aerobic exercise has no obvious effect on low HDL-C levels.High or moderate intensity aerobic exercise can effectively raise the HDL-C level,but there is no significant difference in the fraction of patients reaching normal values between high and moderate intensity aerobic exercise.So moderate intensity is recommended for improving low levels of HDL cholesterol.