中华物理医学与康复杂志
中華物理醫學與康複雜誌
중화물리의학여강복잡지
CHINESE JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION
2013年
3期
190-192
,共3页
脊髓损伤%骨量丢失%脉冲电磁场
脊髓損傷%骨量丟失%脈遲電磁場
척수손상%골량주실%맥충전자장
Spinal cord injury%Bone loss%Pulsed electromagnetic fields%Osteoporosis
目的 探讨脉冲电磁场(PEMFS)治疗对脊髓损伤(SCI)患者骨量丢失的影响.方法 将入选的SCI患者55例按随机数字表法分为治疗组(29例)和对照组(26例),对照组患者给予常规康复治疗;治疗组患者在常规康复治疗的基础上加用PEMFS治疗.2组患者均于治疗前和治疗12周后(治疗后)评定其骨密度和骨代谢生化指标.结果 治疗后,治疗组患者仅转子间的骨密度(0.827 ±0.103) g/cm2与组内治疗前的(0.796±0.092)g/cm2比较,差异无统计学意义(P＞0.05),其股骨颈、大转子、Ward＇s三角区以及总的骨密度值分别为(0.594±0.110) g/cm2、(0.671±0.109) g/cm2、(0.396±0.106) g/cm2、(0.679 ±0.123)g/cm2、较组内治疗前均显著增加(P＜0.05),且股骨颈、大转子、转子间、Ward＇s三角区以及总的骨密度值均明显高于对照组治疗后(P＜0.05).治疗后,治疗组的血清骨钙素(BGP)、尿吡啶啉/肌酐(U-Pyd/Cr)和1,25-二羟基维生素D3[1,25(OH)2D3]3项生化指标分别为(5.76±0.35) ng/ml、(21.6 ±2.51) nm/ml和(10.5±2.75) ng/ml,与组内治疗前和对照组治疗后比较,差异均有统计学意义(P＜0.05).结论 脉冲电磁场可延缓SCI患者的骨量丢失,预防和治疗骨质疏松症.
目的 探討脈遲電磁場(PEMFS)治療對脊髓損傷(SCI)患者骨量丟失的影響.方法 將入選的SCI患者55例按隨機數字錶法分為治療組(29例)和對照組(26例),對照組患者給予常規康複治療;治療組患者在常規康複治療的基礎上加用PEMFS治療.2組患者均于治療前和治療12週後(治療後)評定其骨密度和骨代謝生化指標.結果 治療後,治療組患者僅轉子間的骨密度(0.827 ±0.103) g/cm2與組內治療前的(0.796±0.092)g/cm2比較,差異無統計學意義(P＞0.05),其股骨頸、大轉子、Ward＇s三角區以及總的骨密度值分彆為(0.594±0.110) g/cm2、(0.671±0.109) g/cm2、(0.396±0.106) g/cm2、(0.679 ±0.123)g/cm2、較組內治療前均顯著增加(P＜0.05),且股骨頸、大轉子、轉子間、Ward＇s三角區以及總的骨密度值均明顯高于對照組治療後(P＜0.05).治療後,治療組的血清骨鈣素(BGP)、尿吡啶啉/肌酐(U-Pyd/Cr)和1,25-二羥基維生素D3[1,25(OH)2D3]3項生化指標分彆為(5.76±0.35) ng/ml、(21.6 ±2.51) nm/ml和(10.5±2.75) ng/ml,與組內治療前和對照組治療後比較,差異均有統計學意義(P＜0.05).結論 脈遲電磁場可延緩SCI患者的骨量丟失,預防和治療骨質疏鬆癥.
목적 탐토맥충전자장(PEMFS)치료대척수손상(SCI)환자골량주실적영향.방법 장입선적SCI환자55례안수궤수자표법분위치료조(29례)화대조조(26례),대조조환자급여상규강복치료;치료조환자재상규강복치료적기출상가용PEMFS치료.2조환자균우치료전화치료12주후(치료후)평정기골밀도화골대사생화지표.결과 치료후,치료조환자부전자간적골밀도(0.827 ±0.103) g/cm2여조내치료전적(0.796±0.092)g/cm2비교,차이무통계학의의(P＞0.05),기고골경、대전자、Ward＇s삼각구이급총적골밀도치분별위(0.594±0.110) g/cm2、(0.671±0.109) g/cm2、(0.396±0.106) g/cm2、(0.679 ±0.123)g/cm2、교조내치료전균현저증가(P＜0.05),차고골경、대전자、전자간、Ward＇s삼각구이급총적골밀도치균명현고우대조조치료후(P＜0.05).치료후,치료조적혈청골개소(BGP)、뇨필정람/기항(U-Pyd/Cr)화1,25-이간기유생소D3[1,25(OH)2D3]3항생화지표분별위(5.76±0.35) ng/ml、(21.6 ±2.51) nm/ml화(10.5±2.75) ng/ml,여조내치료전화대조조치료후비교,차이균유통계학의의(P＜0.05).결론 맥충전자장가연완SCI환자적골량주실,예방화치료골질소송증.
Objective To observe any therapeutic effect of pulsed electromagnetic fields (PEMFs) on bone loss in spinal cord injury (SCI) patients.Methods Fifty-five patients with SCI were divided into two groups randomly.The twenty-six patients in the control group (group B) were given only routine rehabilitation treatment; the twenty-six patients in the treatment group (group A) received PEMF therapy in addition.Results After 12 weeks of treatment,the average bone mineral density (BMD) of the proximal femur (including total,neck,Wards,inter,troch) in group A was significantly higher than in group B.The levels of bone-gamma-carboxyglutamic acid containing protein (BGP) and 1,25 (OH)2D3 in group A increased significantly,while they decreased in group B.Urine-pyridinium/crealinine (U-Pyd/Cr) levels in group A decreased significantly,while in group B they were higher than before.There were statistically significant differences between the two groups.Conclusion PEMF treatment can effectively retard bone loss in SCI patients.It has good preventive and curative effects on osteoporosis after SCI.
