CAJ | 학술논문

目的探讨丙泊酚静脉麻醉状态下内镜超声检查术(EUS)与经内镜逆行胰胆管造影术(ERCP)串联诊治胆胰疾病的临床价值.方法回顾性总结105例EUS、ERCP串联执行的胆胰疾病患者(观察组)和90例EUS、ERCP分开执行的胆胰疾病患者(对照组)的临床资料,对比分析操作时间、丙泊酚用量、诊断情况、心肺并发症和内镜并发症发生情况.结果观察组操作时间(78.56±15.88) min、丙泊白酚用量(314.21±223.54) mg,对照组操作时间(97.78±34.56) min、丙泊酚用量(521.23 ±245.12)mg,两组比较差异均有统计学意义(P＜0.05).观察组EUS、ERCP诊断率以及心肺并发症发生率、内镜并发症发生率分别为91.4％ (96/105)、81.9％(86/105)、6.67％(7/105)、3.81％ (4/105),对照组对应分别为94.4％(85/90)、82.2％ (74/90)、5.56％ (5/90)、3.33％ (3/90),两组比较差异均无统计学意义(P＞0.05).结论静脉麻醉状态下EUS、ERCP串联诊治胆胰疾病安全可行,较分开执行可缩短操作时间、减少丙泊酚用量.
목적 탐토병박분정맥마취상태하내경초성검사술(EUS)여경내경역행이담관조영술(ERCP)천련진치담이질병적림상개치.방법 회고성총결105례EUS、ERCP천련집행적담이질병환자(관찰조)화90례EUS、ERCP분개집행적담이질병환자(대조조)적림상자료,대비분석조작시간、병박분용량、진단정황、심폐병발증화내경병발증발생정황.결과 관찰조조작시간(78.56±15.88) min、병박백분용량(314.21±223.54) mg,대조조조작시간(97.78±34.56) min、병박분용량(521.23 ±245.12)mg,량조비교차이균유통계학의의(P＜0.05).관찰조EUS、ERCP진단솔이급심폐병발증발생솔、내경병발증발생솔분별위91.4％ (96/105)、81.9％(86/105)、6.67％(7/105)、3.81％ (4/105),대조조대응분별위94.4％(85/90)、82.2％ (74/90)、5.56％ (5/90)、3.33％ (3/90),량조비교차이균무통계학의의(P＞0.05).결론 정맥마취상태하EUS、ERCP천련진치담이질병안전가행,교분개집행가축단조작시간、감소병박분용량.
Objective To explore the therapeutic value of endoscopic ultrasonography (EUS) combined with endoscopic retrograde cholangiopancreatography (ERCP) for the diagnosis and treatment of pancreaticobiliary diseases.Methods Clinical data were analysed retrospectively in patients who underwent both EUS and ERCP in a single anesthetic session (Group A) and separate procedure in two different sessions (Group B).The following variables of both groups were evaluated:procedural time,propofol dose,cardiopulmonary complications,endoscopic complications and diagnostic yield,and therapeutic procedures.Results Proceduraltime [GroupAvs.GroupB:(78.56 ±-15.88) min vs.(97.78±34.56)min] andthe dose of propofol [Group A vs.Group B:(314.21 ±223.54)mg vs.(521.23 ±245.12)mg] differed significantly between both groups (P ＜ 0.05).In Group A,the diagnostic rates of EUS and ERCP,cardiopulmonary complications rate and endoscopic complications rate were 91.4％ (96/105),81.9％ (86/105),6.67％ (7/105),3.81％ (4/105),respectively,and these variables of group B were 94.4％ (85/90),82.2％ (74/90),5.56％ (5/90),3.33％ (3/90).There were no significant differences in the diagnostic yield,cardiopulmonary complications and endoscopic complications between the two groups (P ＞ 0.05).Conclusion It is safe and feasible that EUS combined with ERCP is performed under anesthesia in a single session.It needs a significantly shorter procedural time and smaller dose of propofol compared with separate procedures for pancreaticobiliary diseases.