中华消化杂志
中華消化雜誌
중화소화잡지
Chinese Journal of Digestion
2013年
1期
33-36
,共4页
张宝燕%李向红%袁静%吕有勇
張寶燕%李嚮紅%袁靜%呂有勇
장보연%리향홍%원정%려유용
胃肿瘤%回顾性研究%腺癌%癌,印戒细胞%淋巴转移
胃腫瘤%迴顧性研究%腺癌%癌,印戒細胞%淋巴轉移
위종류%회고성연구%선암%암,인계세포%림파전이
Stomach neoplasms%Retrospective studies%Adenocarcinoma%Carcinoma,signet ring cell%Lymphatic metastasis
目的 探讨胃癌临床病理特点,为胃癌的研究和治疗提供基础.方法 收集2001至2004年行胃癌根治术的病例共694例,回顾性分析性别、年龄、肿瘤部位、肿瘤大小、WHO组织学分型和分级、Lauren分型、脉管侵犯、淋巴结转移、肿瘤浸润深度(pT)、病理TNM分期(pTNM).结果 694例胃癌中,男女比为3.96∶1;41～70岁组有644例,占92.80％,51～70岁为高发年龄段.胃癌好发部位依次为贲门(33.43％)、胃窦(28.96％)、胃体(21.76％).常见的WHO组织学类型依次是管状腺癌(70.32％)、印戒细胞癌(24.50％).常见的组织学分级依次为Ⅱ、Ⅲ、Ⅰ级.Lauren分型以肠型最常见,占58.93％,其次是弥漫型,占22.33％.手术时438例(63.11％)有脉管侵犯,504例(72.62％)有淋巴结转移,319例(45.97％)处于pT3期,241例(34.73％)处于pTNMⅢ期.结论 近年胃癌在贲门、胃窦好发,管状腺癌和印戒细胞癌常见,提示胃癌发病机制存在多元性.
目的 探討胃癌臨床病理特點,為胃癌的研究和治療提供基礎.方法 收集2001至2004年行胃癌根治術的病例共694例,迴顧性分析性彆、年齡、腫瘤部位、腫瘤大小、WHO組織學分型和分級、Lauren分型、脈管侵犯、淋巴結轉移、腫瘤浸潤深度(pT)、病理TNM分期(pTNM).結果 694例胃癌中,男女比為3.96∶1;41～70歲組有644例,佔92.80％,51～70歲為高髮年齡段.胃癌好髮部位依次為賁門(33.43％)、胃竇(28.96％)、胃體(21.76％).常見的WHO組織學類型依次是管狀腺癌(70.32％)、印戒細胞癌(24.50％).常見的組織學分級依次為Ⅱ、Ⅲ、Ⅰ級.Lauren分型以腸型最常見,佔58.93％,其次是瀰漫型,佔22.33％.手術時438例(63.11％)有脈管侵犯,504例(72.62％)有淋巴結轉移,319例(45.97％)處于pT3期,241例(34.73％)處于pTNMⅢ期.結論 近年胃癌在賁門、胃竇好髮,管狀腺癌和印戒細胞癌常見,提示胃癌髮病機製存在多元性.
목적 탐토위암림상병리특점,위위암적연구화치료제공기출.방법 수집2001지2004년행위암근치술적병례공694례,회고성분석성별、년령、종류부위、종류대소、WHO조직학분형화분급、Lauren분형、맥관침범、림파결전이、종류침윤심도(pT)、병리TNM분기(pTNM).결과 694례위암중,남녀비위3.96∶1;41～70세조유644례,점92.80％,51～70세위고발년령단.위암호발부위의차위분문(33.43％)、위두(28.96％)、위체(21.76％).상견적WHO조직학류형의차시관상선암(70.32％)、인계세포암(24.50％).상견적조직학분급의차위Ⅱ、Ⅲ、Ⅰ급.Lauren분형이장형최상견,점58.93％,기차시미만형,점22.33％.수술시438례(63.11％)유맥관침범,504례(72.62％)유림파결전이,319례(45.97％)처우pT3기,241례(34.73％)처우pTNMⅢ기.결론 근년위암재분문、위두호발,관상선암화인계세포암상견,제시위암발병궤제존재다원성.
Objective To explore the clinical pathological features of gastric cancer and to provide a basis for research and treatment of gastric cancer.Methods From 2001 to 2004,a total of 694 cases of gastric cancer with radical gastrectomy were collected.Gender,age,tumor location,tumor size,World Health Organization (WHO) histological type and grade,Lauren type,blood/lymphatic vessel invasion,lymph node metastasis,depth of tumor invasion (pT) and pathological TNM staging (pTNM) were retrospectively analyzed.Results Among 694 gastric cancer cases,male to female ratio was 3.96∶ 1; a total of 644 cases (92.8％) were aged from 41 to 70,and cases aged from 51 to 70 had a high incidence of gastric cancer.The predilection site for gastric cancer was cardia (33.43％),antrum (28.96％) and the body (21.76％) accordingly.The common WHO histological types were tubular adenocarcinoma (70.32 ％) and signet ring cell carcinoma (24.50 ％).The common histological grades were Ⅱ,Ⅲ and Ⅰ.The intestinal type was most common in Lauren classification,accounting for 58.93 ％; followed by the diffuse type,accounting for 22.33 ％.Blood/lymphatic vessel invasion was detected in 438 cases (63.11％),lymphnode metastasis in 504 cases (72.62％).A total of 319 cases (45.97％) were pT3 stage,241 cases (34.73％) were on pTNM Ⅲ stage.Conclusions In recent years,cardia and antrum are the predilection sites of gastric cancer.Tubular adenocarcinoma and signet ring cell carcinoma are common which indicate that the mechanism of gastric cancer pathogenesis is varied.
