中华消化杂志
中華消化雜誌
중화소화잡지
Chinese Journal of Digestion
2014年
4期
244-246
,共3页
姚东英%胡晔东%奚慧敏%孙梅%刘菲
姚東英%鬍曄東%奚慧敏%孫梅%劉菲
요동영%호엽동%해혜민%손매%류비
酸袋%胃食管反流病%食管活动障碍
痠袋%胃食管反流病%食管活動障礙
산대%위식관반류병%식관활동장애
Acid pocket%Gastroesophageal reflux disease%Esophageal motility disorders
目的 探讨酸袋与GERD酸反流的关系.方法 选择2011年3月至2012年1月的GERD患者29例,并以9名健康者为对照.所有研究对象均接受食管测压、酸袋检测、酸袋出现时间检测和食管24 h动态pH监测.组间比较行t检验.采用Logistic回归法分析GERD发病与酸袋间的关系.采用Pearson法进行相关性分析.结果 GERD组和对照组中有酸袋者所占比例分别为58.6％(17/29)和5/9,差异无统计学意义(P＞0.05).GERD组中有酸袋者的酸袋持续时间[(56.3±44.7) min]长于对照组中有酸袋者[(16.0±8.2) min],差异有统计学意义(t=1.970,P＜0.01).GERD组中有酸袋者的酸袋平均pH值(2.8±1.3)与对照组中有酸袋者(1.9±0.5)比较差异无统计学意义(P＞0.05).GERD组中有酸袋者的酸袋持续时间与最长反流时间相关(r=0.550,P＜0.01).GERD组的食管动力峰值速度[(3.3±0.6) cm/s]低于对照组[(5.0±4.1)cm/s],差异有统计学意义(t=-1.354,P＜0.05).GERD组中有酸袋者的食管动力峰值速度[(3.2±0.6)cm/s]低于对照组中有酸袋者[(7.2±6.3) cm/s],差异有统计学意义(t=-2.693,P＜0.05).结论 GERD患者酸袋持续时间与酸反流间存在相关性.食管运动功能异常可能与GERD发病和酸袋发生有关.
目的 探討痠袋與GERD痠反流的關繫.方法 選擇2011年3月至2012年1月的GERD患者29例,併以9名健康者為對照.所有研究對象均接受食管測壓、痠袋檢測、痠袋齣現時間檢測和食管24 h動態pH鑑測.組間比較行t檢驗.採用Logistic迴歸法分析GERD髮病與痠袋間的關繫.採用Pearson法進行相關性分析.結果 GERD組和對照組中有痠袋者所佔比例分彆為58.6％(17/29)和5/9,差異無統計學意義(P＞0.05).GERD組中有痠袋者的痠袋持續時間[(56.3±44.7) min]長于對照組中有痠袋者[(16.0±8.2) min],差異有統計學意義(t=1.970,P＜0.01).GERD組中有痠袋者的痠袋平均pH值(2.8±1.3)與對照組中有痠袋者(1.9±0.5)比較差異無統計學意義(P＞0.05).GERD組中有痠袋者的痠袋持續時間與最長反流時間相關(r=0.550,P＜0.01).GERD組的食管動力峰值速度[(3.3±0.6) cm/s]低于對照組[(5.0±4.1)cm/s],差異有統計學意義(t=-1.354,P＜0.05).GERD組中有痠袋者的食管動力峰值速度[(3.2±0.6)cm/s]低于對照組中有痠袋者[(7.2±6.3) cm/s],差異有統計學意義(t=-2.693,P＜0.05).結論 GERD患者痠袋持續時間與痠反流間存在相關性.食管運動功能異常可能與GERD髮病和痠袋髮生有關.
목적 탐토산대여GERD산반류적관계.방법 선택2011년3월지2012년1월적GERD환자29례,병이9명건강자위대조.소유연구대상균접수식관측압、산대검측、산대출현시간검측화식관24 h동태pH감측.조간비교행t검험.채용Logistic회귀법분석GERD발병여산대간적관계.채용Pearson법진행상관성분석.결과 GERD조화대조조중유산대자소점비례분별위58.6％(17/29)화5/9,차이무통계학의의(P＞0.05).GERD조중유산대자적산대지속시간[(56.3±44.7) min]장우대조조중유산대자[(16.0±8.2) min],차이유통계학의의(t=1.970,P＜0.01).GERD조중유산대자적산대평균pH치(2.8±1.3)여대조조중유산대자(1.9±0.5)비교차이무통계학의의(P＞0.05).GERD조중유산대자적산대지속시간여최장반류시간상관(r=0.550,P＜0.01).GERD조적식관동력봉치속도[(3.3±0.6) cm/s]저우대조조[(5.0±4.1)cm/s],차이유통계학의의(t=-1.354,P＜0.05).GERD조중유산대자적식관동력봉치속도[(3.2±0.6)cm/s]저우대조조중유산대자[(7.2±6.3) cm/s],차이유통계학의의(t=-2.693,P＜0.05).결론 GERD환자산대지속시간여산반류간존재상관성.식관운동공능이상가능여GERD발병화산대발생유관.
Objective To explore the relationship between acid pocket and acid reflux in gastroesophageal reflux disease (GERD).Methods From March 2011 to January 2012,29 patients with GERD were enrolled and nine healthy individuals were set as control.All objects of this study accepted esophageal manometry test,acid pocket test,test of the occurrence time of acid pocket and ambulatory 24 hours pH monitoring.The t-test was performed for comparison between two groups.The relationship between the incidence of GERD and acid pocket was analyzed by Logistic regression analysis.Pearson correlation analysis was used for correlation analysis.Results The percentage of acid pocket in GERD group and control group was 58.6％ (17/29) and 5/9,respectively,and the difference was not statistically significantly (P＞0.05).The duration time of acid pocket was (56.3±44.7) minutes in GERD group which was longer than that of control group ((16.0±8.2) minutes) and the difference was statistically significant (t=1.970,P＜0.01).There was no statistical significance in the average pH value of acid pocket between GERD group with acid pocket (2.8 ± 1.3) and that of control group with acid pocket (1.9±0.5,P＞0.05).The duration time of acid pocket was correlated with the longest reflux time in GERD group with acid pocket (r=0.550,P＜0.01).The peak velocity of esophageal motility in GERD group ((3.3±0.6) cm/s) was lower than that of control group ((5.0±4.1) cm/s) and the difference was statistically significant (t=-1.354,P＜0.05).The peak velocity of esophageal motility in GERD group with acid pocket ((3.2±0.6) cm/s) was lower than that of control group with acid pocket ((7.2± 6.3) cm/s) and the difference was statistically significant (t=-2.693,P＜0.05).Conclusions The duration time of acid pocket in GERD is correlated with the time of acid reflux.Esophageal dysmotility may be related with the pathogenesis of GERD and the occurrence of acid pocket.
