CAJ | 학술논문

目的探讨行外科手术的恶性腹膜间皮瘤患者的临床特点.方法回顾性分析2008年4月至2012年11月14例行外科手术并最终病理确诊为恶性腹膜间皮瘤患者的临床资料.结果 14例患者中,有石棉接触史13例;腹痛10例,腹胀7例,阴道间断出血1例;有石棉斑13例;器官浸润14例,少量或无腹水9例,腹腔轻度淋巴结肿大1例,均未发现远处器官转移.弥漫型3例,局限型11例;血清CA125升高7例,7例术后行化学疗法,术后生存期平均为5个月,至截稿时2例腹膜病变局限的患者仍存活.结论本组恶性腹膜间皮瘤患者发病与石棉接触密切相关,以局限型为主,无淋巴结肿大和远处器官转移,早期患者手术切除可提高生存率.
목적 탐토행외과수술적악성복막간피류환자적림상특점.방법 회고성분석2008년4월지2012년11월14례행외과수술병최종병리학진위악성복막간피류환자적림상자료.결과 14례환자중,유석면접촉사13례;복통10례,복창7례,음도간단출혈1례;유석면반13례;기관침윤14례,소량혹무복수9례,복강경도림파결종대1례,균미발현원처기관전이.미만형3례,국한형11례;혈청CA125승고7례,7례술후행화학요법,술후생존기평균위5개월,지절고시2례복막병변국한적환자잉존활.결론 본조악성복막간피류환자발병여석면접촉밀절상관,이국한형위주,무림파결종대화원처기관전이,조기환자수술절제가제고생존솔.
Objective To explore the clinical features of patients with surgical malignant peritoneal mesothelioma.Methods From April 2008 to November 2012,the clinical data of 14 patients with surgery and pathologically diagnosed malignant peritoneal mesothelioma were retrospectively analyzed.Results Among the 14 patients,13 cases had a history of asbestos exposure.There were 10 cases with abdominal pain,seven cases with bloatting,and one case with intermittent vaginal bleeding.There were 13 cases with asbestos plaques,14 cases with organ infiltration,nine cases with little or no ascites,one case with mild lymph nodes enlargement in peritoneal cavity,but no case was found with distant metastasis.There were three cases with diffuse type and 11 cases with localized type.Serum CA125 level increased in seven cases.Seven cases received postoperative chemotherapy,and the average survival time was five months after surgery.To the closing date,two patients with localized peritoneal lesions are still alive.Conclusions The incidence of the group of patients with malignant peritoneal mesothelioma is closely related to the contact with asbestos.Localized type is the dominant type,without lymph nodes enlargement and distant metastases.Survival rate may improve in patients with early surgery.