CAJ | 학술논문

目的监测广州市番禺区全年龄组农民急性冠心病事件的发病水平及长期变化趋势,为疾病防治提供依据.方法 1991至2001年、2010至2011年在广州市番禺区对中美心肺疾病流行病学合作研究的监测人群进行监测.采用世界标准人口进行标化,按年度、性别、年龄分别计算急性冠心病事件发病粗率和年龄标化率；比较该人群在2个不同时期冠心病事件的发病特点；采用回归分析法计算急性冠心病事件发病率的年均变化率,并进行统计学分析.结果 1991至2001年,番禺区女性农民急性冠心病事件发病率呈上升趋势(P＜0.05).番禺区农民急性冠心病事件年龄标化发病率2010至2011年为28.50/10万(粗率为34.06/10万),1991至2001年为15.57/10万(粗率为16.14/10万),标化率增长了83.04％.男性发病高峰年龄在75～ 79岁,女性在80～84岁.男性发病率增长幅度最大的是35～39岁年龄段,其次是75～ 79岁年龄段；女性发病率增长幅度最大的是50～ 54岁年龄段,其次是65～ 69岁年龄段.2010至2011年75岁及以上患者占全部发病人数的47.37％(36/76),较1991至2001年(33.73％,56/166)增长了40.44％.结论广州市番禺区农民急性冠心病事件的发病率处于国内中等偏低水平,20年来呈平缓上升趋势；番禺区的冠心病防治应针对发病率增幅较大的特定年龄人群.
목적 감측엄주시번우구전년령조농민급성관심병사건적발병수평급장기변화추세,위질병방치제공의거.방법 1991지2001년、2010지2011년재엄주시번우구대중미심폐질병류행병학합작연구적감측인군진행감측.채용세계표준인구진행표화,안년도、성별、년령분별계산급성관심병사건발병조솔화년령표화솔；비교해인군재2개불동시기관심병사건적발병특점；채용회귀분석법계산급성관심병사건발병솔적년균변화솔,병진행통계학분석.결과 1991지2001년,번우구녀성농민급성관심병사건발병솔정상승추세(P＜0.05).번우구농민급성관심병사건년령표화발병솔2010지2011년위28.50/10만(조솔위34.06/10만),1991지2001년위15.57/10만(조솔위16.14/10만),표화솔증장료83.04％.남성발병고봉년령재75～ 79세,녀성재80～84세.남성발병솔증장폭도최대적시35～39세년령단,기차시75～ 79세년령단；녀성발병솔증장폭도최대적시50～ 54세년령단,기차시65～ 69세년령단.2010지2011년75세급이상환자점전부발병인수적47.37％(36/76),교1991지2001년(33.73％,56/166)증장료40.44％.결론 엄주시번우구농민급성관심병사건적발병솔처우국내중등편저수평,20년래정평완상승추세；번우구적관심병방치응침대발병솔증폭교대적특정년령인군.
Objective To monitor the incidence change of acute coronary heart events in the allages farmers in Panyu District,Guangzhou City during 1991-2001 and 2010-2011.Methods The surveillance on the same defined population as that from the PRC-USA cooperative epidemiologic project on the cardiovascular and pulmonary diseases 30-year ago was carried out in Panyu,Guangzhou in 1991-2001 and 2010-2011.The crude incidence of acute coronary events and the age-standardized incidence rate were calculated by the year,gender and age,and standardized with the world standard population age distribution.Incidences at the two different periods were compared.The annual average changing rate of the incidence was obtained by the regression analysis methods.Results In the 11 consecutive years of 1991-2001,a upward trend on the incidence of acute coronary events among the farmers in women in Panyu District was found (P ＜ 0.05).The incidence of the acute coronary events in the year of 2010-2011 was significantly higher than that in the year of 1991 to 2001 [34.06 per 100 000 (age-adjusted rate as 28.50 per 100 000) versus 16.14 per 100 000 (age-adjusted rate as 16.57 per 100 000),P ＜0.05].The ageadjusted rate increased by 83.04％.Peak incidence of acute coronary events in males was noticed in 75-79 age group,and in 80-84 age group in females.Comparing to the period of 1991-2001,the largest incidence increases appeared in the age groups of 35-39 and 75-79 years in males,while in the age groups of 50-54 and 65-69 years in females.Up to 47.37％ (36/76) events occurred on the age group older than 75 years,raised by 40.44％ comparing to that in 1991-2001 (33.73％,56/166).Conclusions The incidence of acute coronary events among farmers in Panyu District is at middle or low level of China but there is an increasing trend in acute coronary incidence from 1991 to 2011.Our results suggest that the prevention and treatment on acute coronary syndrome should be strengthened,and especially on the age group with the largest increase of disease incidence.