中华心血管病杂志
中華心血管病雜誌
중화심혈관병잡지
Chinese Journal of Cardiology
2014年
9期
736-739
,共4页
卜晓佳%吕蓉%季诗明%梁涛%郭希娟
蔔曉佳%呂蓉%季詩明%樑濤%郭希娟
복효가%려용%계시명%량도%곽희연
心力衰竭,充血性%认知障碍
心力衰竭,充血性%認知障礙
심력쇠갈,충혈성%인지장애
Heart failure,congestive%Cognition disorders
目的 描述慢性心力衰竭(chronic heart failure,CHF)患者认知功能状况并探讨其影响因素.方法 入选2013年4月至12月北京阜外心血管病医院CHF监护病房及重症监护病房(ICU)住院的CHF患者267例,使用蒙特利尔认知功能评估表(MoCA)进行认知功能评估,并收集相关资料.以患者认知状况为因变量进行非条件logistic回归分析.结果 患者认知评估平均分为(25.22±2.82)分,以＜ 26分作为认知功能受损的界值,37.8％ (101/267)的患者伴有认知功能损伤.其中延迟回忆、语言、视空间与执行功能维度受损最严重.多因素分析结果显示,在对其他因素进行控制后,随年龄增长患者认知功能呈下降趋势(OR=1.09,95％ CI:1.05～1.14),左心室射血分数(LVEF)越高患者认知功能越好(OR =0.97,95％ CI:0.95 ～0.99),规律服药者认知功能好于未规律服药者(OR =3.71,95％ CI:1.40 ～ 10.91),社会支持水平高的患者认知功能优于社会支持低者(OR=0.92,95％ CI:0.88 ～0.96).结论 CHF患者认知损伤发生率较高,年龄、LVEF、规律服药情况及社会支持与CHF患者认知功能有关.
目的 描述慢性心力衰竭(chronic heart failure,CHF)患者認知功能狀況併探討其影響因素.方法 入選2013年4月至12月北京阜外心血管病醫院CHF鑑護病房及重癥鑑護病房(ICU)住院的CHF患者267例,使用矇特利爾認知功能評估錶(MoCA)進行認知功能評估,併收集相關資料.以患者認知狀況為因變量進行非條件logistic迴歸分析.結果 患者認知評估平均分為(25.22±2.82)分,以＜ 26分作為認知功能受損的界值,37.8％ (101/267)的患者伴有認知功能損傷.其中延遲迴憶、語言、視空間與執行功能維度受損最嚴重.多因素分析結果顯示,在對其他因素進行控製後,隨年齡增長患者認知功能呈下降趨勢(OR=1.09,95％ CI:1.05～1.14),左心室射血分數(LVEF)越高患者認知功能越好(OR =0.97,95％ CI:0.95 ～0.99),規律服藥者認知功能好于未規律服藥者(OR =3.71,95％ CI:1.40 ～ 10.91),社會支持水平高的患者認知功能優于社會支持低者(OR=0.92,95％ CI:0.88 ～0.96).結論 CHF患者認知損傷髮生率較高,年齡、LVEF、規律服藥情況及社會支持與CHF患者認知功能有關.
목적 묘술만성심력쇠갈(chronic heart failure,CHF)환자인지공능상황병탐토기영향인소.방법 입선2013년4월지12월북경부외심혈관병의원CHF감호병방급중증감호병방(ICU)주원적CHF환자267례,사용몽특리이인지공능평고표(MoCA)진행인지공능평고,병수집상관자료.이환자인지상황위인변량진행비조건logistic회귀분석.결과 환자인지평고평균분위(25.22±2.82)분,이＜ 26분작위인지공능수손적계치,37.8％ (101/267)적환자반유인지공능손상.기중연지회억、어언、시공간여집행공능유도수손최엄중.다인소분석결과현시,재대기타인소진행공제후,수년령증장환자인지공능정하강추세(OR=1.09,95％ CI:1.05～1.14),좌심실사혈분수(LVEF)월고환자인지공능월호(OR =0.97,95％ CI:0.95 ～0.99),규률복약자인지공능호우미규률복약자(OR =3.71,95％ CI:1.40 ～ 10.91),사회지지수평고적환자인지공능우우사회지지저자(OR=0.92,95％ CI:0.88 ～0.96).결론 CHF환자인지손상발생솔교고,년령、LVEF、규률복약정황급사회지지여CHF환자인지공능유관.
Objective To explore the cognitive function status and potential influence factors on cognitive function in hospitalized patients with chronic heart failure.Methods Using a cross-sectional research design,CHF patients(n =267,mean age (63.8 ± 9.4) years) were recruited from two care unitsHeart Failure Care Unit and Intensive Care Unit of our hospital.Cognitive function status was evaluated by the Montreal Cognitive Assessment (MoCA) screen test.Results Based on the MoCA score,37.8％ (101/267) patients suffered from cognitive impairment (score ＜ 26),especially on the three specific cognitive functions-memory,langue and executive capability.Multifactorial analysis showed that after controlling for other factors,there was a downward trend on cognitive function with aging (OR =1.09,95％ CI:1.05-1.14) while higher left ventricular ejection fraction (LVEF) was related to better cognitive function (OR =0.97,95％ CI:0.95-0.99) ; patients who took medicine regularly also had better cognitive function (OR =3.71,95％CI:1.40-10.91); cognitive function was better in patients with high level of social support compared those with low social support (OR =0.92,95％ CI:0.88-0.96).Conclusions Incidence of cognitive impairment is high in hospitalized patients with chronic heart failure.Age,LVEF,whether taking medication regularly and social support are factors related to cognitive function in CHF patients.
