中华胸心血管外科杂志
中華胸心血管外科雜誌
중화흉심혈관외과잡지
Chinese Journal of Thoracic and Cardiovascular Surgery
2012年
10期
588-590
,共3页
潘燕军%张海波%郑景浩%王顺民%徐志伟
潘燕軍%張海波%鄭景浩%王順民%徐誌偉
반연군%장해파%정경호%왕순민%서지위
主动脉瓣狭窄%心脏缺损,先天性%交界切开术%心脏瓣膜成形术
主動脈瓣狹窄%心髒缺損,先天性%交界切開術%心髒瓣膜成形術
주동맥판협착%심장결손,선천성%교계절개술%심장판막성형술
Aortic stenosis%Heart defects,congenital%Valvotomy%Cardiac valve annuloplasty
目的 回顾性总结先天性主动脉瓣狭窄患儿手术治疗的效果及经验.方法 2006年2月至2011年11月,共收治49例先天性主动脉瓣狭窄患儿,男29例,女20例;年龄1个月~ 14岁;体质量3.2 ~47.0 kg.轻度狭窄2例,中度狭窄21例,重度狭窄26例.术前跨瓣压差45~123 mm Hg(1 mm Hg =0.133 kPa),平均(74.9±20.4)mm Hg.单纯主动脉瓣狭窄14例,伴有中—重度反流4例.伴其他心内畸形33例,包括室间隔缺损、房间隔缺损、动脉导管未闭、主动脉缩窄、左心室流出道狭窄、二尖瓣瓣上环等.行主动脉瓣交界切开术31例,主动脉瓣成形术9例,主动脉瓣置换术2例,Ross手术1例,Ross-Konno手术2例,Konno+主动脉瓣置换术4例.术后随访2~55个月,平均20个月.评估患儿心功能、主动脉瓣跨瓣压差及瓣膜反流程度.结果 死亡1例,生存患儿术后心功能良好,左心室射血分数0.69±0.10,短轴缩短分数0.38±0.09.术后跨瓣压差20 ~ 73 mm Hg,平均(38.6±15.8)mm Hg,较术前降低(36.2±18.3)mm Hg(P <0.001).40例患儿行主动脉瓣交界切开和成形,术后主动脉瓣反流程度为无或轻微8例,轻度25例,中度7例.1例主动脉瓣交界切开术后因切开处复粘连再次行交界切开术.结论 先天性主动脉瓣狭窄的患儿如无明显反流,可行主动脉瓣交界切开术或同时行主动脉瓣成形术,如果反流中度以上,则需根据患儿年龄等情况选择合适的手术方法.
目的 迴顧性總結先天性主動脈瓣狹窄患兒手術治療的效果及經驗.方法 2006年2月至2011年11月,共收治49例先天性主動脈瓣狹窄患兒,男29例,女20例;年齡1箇月~ 14歲;體質量3.2 ~47.0 kg.輕度狹窄2例,中度狹窄21例,重度狹窄26例.術前跨瓣壓差45~123 mm Hg(1 mm Hg =0.133 kPa),平均(74.9±20.4)mm Hg.單純主動脈瓣狹窄14例,伴有中—重度反流4例.伴其他心內畸形33例,包括室間隔缺損、房間隔缺損、動脈導管未閉、主動脈縮窄、左心室流齣道狹窄、二尖瓣瓣上環等.行主動脈瓣交界切開術31例,主動脈瓣成形術9例,主動脈瓣置換術2例,Ross手術1例,Ross-Konno手術2例,Konno+主動脈瓣置換術4例.術後隨訪2~55箇月,平均20箇月.評估患兒心功能、主動脈瓣跨瓣壓差及瓣膜反流程度.結果 死亡1例,生存患兒術後心功能良好,左心室射血分數0.69±0.10,短軸縮短分數0.38±0.09.術後跨瓣壓差20 ~ 73 mm Hg,平均(38.6±15.8)mm Hg,較術前降低(36.2±18.3)mm Hg(P <0.001).40例患兒行主動脈瓣交界切開和成形,術後主動脈瓣反流程度為無或輕微8例,輕度25例,中度7例.1例主動脈瓣交界切開術後因切開處複粘連再次行交界切開術.結論 先天性主動脈瓣狹窄的患兒如無明顯反流,可行主動脈瓣交界切開術或同時行主動脈瓣成形術,如果反流中度以上,則需根據患兒年齡等情況選擇閤適的手術方法.
목적 회고성총결선천성주동맥판협착환인수술치료적효과급경험.방법 2006년2월지2011년11월,공수치49례선천성주동맥판협착환인,남29례,녀20례;년령1개월~ 14세;체질량3.2 ~47.0 kg.경도협착2례,중도협착21례,중도협착26례.술전과판압차45~123 mm Hg(1 mm Hg =0.133 kPa),평균(74.9±20.4)mm Hg.단순주동맥판협착14례,반유중—중도반류4례.반기타심내기형33례,포괄실간격결손、방간격결손、동맥도관미폐、주동맥축착、좌심실류출도협착、이첨판판상배등.행주동맥판교계절개술31례,주동맥판성형술9례,주동맥판치환술2례,Ross수술1례,Ross-Konno수술2례,Konno+주동맥판치환술4례.술후수방2~55개월,평균20개월.평고환인심공능、주동맥판과판압차급판막반류정도.결과 사망1례,생존환인술후심공능량호,좌심실사혈분수0.69±0.10,단축축단분수0.38±0.09.술후과판압차20 ~ 73 mm Hg,평균(38.6±15.8)mm Hg,교술전강저(36.2±18.3)mm Hg(P <0.001).40례환인행주동맥판교계절개화성형,술후주동맥판반류정도위무혹경미8례,경도25례,중도7례.1례주동맥판교계절개술후인절개처복점련재차행교계절개술.결론 선천성주동맥판협착적환인여무명현반류,가행주동맥판교계절개술혹동시행주동맥판성형술,여과반류중도이상,칙수근거환인년령등정황선택합괄적수술방법.
Objective To studiy the surgical outcomes of children with congenital aortic stenosis (AS),and summarized the experience of surgical procedures.Methods From February 2006 to November 2011,a total of 49 consecutive children with AS underwent surgical treatments.Twenty-nine patients were male and 20 patients were female.The median age was 17 months (1 month to 14 years),and median weight was 15.6 kg (3.2-47.0 kg).Peak AS gradients was (74.9 ±20.4)mmHg (45-123 mm Hg) before surgery.Fourteen patients had isolated congenital AS,4 had combined moderate-to-severe aortic insufficiency (AI).Thirty-Three patients had associated cardiac anomalies,including ventricular septal defect,atrial septal defect,patent ductus ateriosus,coarctation of aorta,subaortic stenosis,and supravalvular mitral stenosis.Thirty-one patients underwent aortic valvotomy,9 valvuloplasty,2 Aortic valve replacement (AVR),1 Ross procedure,2 Ross-Konno procedure,and 4 Konno/AVR.Median follow-up was 20 months (2-55 months).Clinical and echocardiographic follow-up data were analyzed.Results There was 1 postoperative death who died of heart failure due to severe mitral valve insuffciency.Latest follow-up data showed that the survivals performed in satisfactory cardiac function.Left ventricular ejection fraction (LVEF)was 0.69 ±0.10,and fraction shortening (FS) was 0.38 ±0.09.Peak AS gradients decreased significantly after surgery to (38.6 ± 15.8) mm Hg (20-73 mm Hg),P < 0.001.One patient needed reintervention because of severe recurrence of adhesion in the commissure 3 months after the previous surgery.Totally 31 patients underwent simple valvotomy procedure.Postoperative AI was none or trace in 5,mild in 20,and moderate in 6.Two surgical techniques were used to repair the aortic valve according to the anatomy of the valve and the cause of insufficiency,including commissuroplasty in 6 and pericarial casp extension in 3.Nine patients underwent valvuloplasty procedure,post-operative AI was none or trace in 3,mild in 5,and moderate in 1.We put more attention to the 7 patients who had moderate AI valvotomy or valvuloplasty,and the latest follow-up showed that these patients were in good condition and there was no deterioration the degree of AI.Conclusion Long-term outcomes show that aortic valvotomy and valvuloplasty are reliable and effective approaches for congenital AS in children.When moderate-to-severe AI exists,other procedures such as Ross,Ross-Konno,AVR,or Konno/AVR are preferred.