CAJ | 학술논문

目的探讨良性疾病全肺切除术的手术指征和术后近期并发症的影响因素.方法回顾性分析136例良性疾病全肺切除术患者的临床资料,随访术后30天内发生的并发症.采用单因素和多因素分析良性疾病全肺切除术后并发症发生的危险因素.结果 33例(24.26％)出现术后并发症,围术期死亡5例(3.68％).单因素分析显示疾病类型(P=0.041)、术侧(P =0.014)、出血量(P=0.010)及手术持续时间(P =0.009)是术后并发症的主要影响因素.多因素分析显示疾病类型(HR3.158,95％ CI 1.248～7.992,P=0.015)和手术持续时间(HR2.508,95％ CI 1.035 ～6.080,P=0.042)为良性病变全肺切除术后发生并发症的独立危险因素.结论良性疾病全肺切除术后伴有高并发症发生率.但通过严格掌握手术适应证和科学合理进行围术期管理可以有效降低围术期死亡率和并发症发生率.全肺切除仍然可以作为良性肺疾病治疗的选择.
목적 탐토량성질병전폐절제술적수술지정화술후근기병발증적영향인소.방법 회고성분석136례량성질병전폐절제술환자적림상자료,수방술후30천내발생적병발증.채용단인소화다인소분석량성질병전폐절제술후병발증발생적위험인소.결과 33례(24.26％)출현술후병발증,위술기사망5례(3.68％).단인소분석현시질병류형(P=0.041)、술측(P =0.014)、출혈량(P=0.010)급수술지속시간(P =0.009)시술후병발증적주요영향인소.다인소분석현시질병류형(HR3.158,95％ CI 1.248～7.992,P=0.015)화수술지속시간(HR2.508,95％ CI 1.035 ～6.080,P=0.042)위량성병변전폐절제술후발생병발증적독립위험인소.결론 량성질병전폐절제술후반유고병발증발생솔.단통과엄격장악수술괄응증화과학합리진행위술기관리가이유효강저위술기사망솔화병발증발생솔.전폐절제잉연가이작위량성폐질병치료적선택.
Objective To investigate indications and early postoperative morbidity of patients who underwent pneumonectomy for benign lung disease.Methods We retrospectively analysed 136 patients with benign lung diseases undergone pneumonectomy,and collected clinical database about early postoperative complications.We used log-rank test and Cox proportional hazards methods to identify potential independent risk factors for early postoperative complications after pneumonectomy for benign disease.Results The early morbidity and mortality were 24.6％,3.68％,respectively.Univariate analysis showed etiology (P =0.041),anatomical side (P =0.014),blood loss (P =0.010) and duration of operation (P =0.009)were the risk factors of early complications after pneumonectomy for benign disease.However,etiology(HR 3.158,95％ CI 1.248-7.992,P =0.015) and duration of operation (HR 2.508,95 ％ CI 1.035-6.080,P =0.042) were the independent risk factors.Conclusion Pneunonectomy for benign lung disease is a high-risk procedure that is performed for a variety of indications,but it can effectively reduce postoperative mortality and morbidity through the strict indication of operation and scientific perioperative management.Pneumonectomy for benign disease should be considered a treatment option for carefully selected patients.