CAJ | 학술논문

目的报道2例主动脉夹层合并慢性弥散性血管内凝血(DIC)的患者,并探讨此类病例的治疗方案.方法对2例主动脉夹层合并慢性DIC患者的临床资料及治疗方案进行分析并复习相关文献.结果例1,女,53岁,齿龈渗血、皮肤散在瘀斑及血尿2个月,PLT 48×109/L,APTT 38.0 s,纤维蛋白原0.53 g/L;例2,男,86岁,皮肤出血点、瘀斑伴齿龈出血2周,PLT 17×109/L,APTT 37.5 s,纤维蛋白原0.51 g/L.2例患者CT检查均示主动脉夹层,诊断为主动脉夹层相关慢性DIC,予输注血浆、血小板及纤维蛋白原等替代治疗后临床症状均有好转.结论充分的替代治疗可改善部分主动脉夹层相关慢性DIC患者的凝血异常.
목적 보도2례주동맥협층합병만성미산성혈관내응혈(DIC)적환자,병탐토차류병례적치료방안.방법 대2례주동맥협층합병만성DIC환자적림상자료급치료방안진행분석병복습상관문헌.결과 례1,녀,53세,치간삼혈、피부산재어반급혈뇨2개월,PLT 48×109/L,APTT 38.0 s,섬유단백원0.53 g/L;례2,남,86세,피부출혈점、어반반치간출혈2주,PLT 17×109/L,APTT 37.5 s,섬유단백원0.51 g/L.2례환자CT검사균시주동맥협층,진단위주동맥협층상관만성DIC,여수주혈장、혈소판급섬유단백원등체대치료후림상증상균유호전.결론 충분적체대치료가개선부분주동맥협층상관만성DIC환자적응혈이상.
Objective To report two cases of chronic disseminated intravascular coagulation associated (DIC) with aortic dissecting aneurysm,and discuss the treatment strategy.Methods The clinical data of two patients with chronic DIC associated with aortic dissecting aneurysm were analyzed and the related literature was reviewed.Results Case 1:female,53 years old,she had gingival bleeding,skin ecchymosis and haematuria for 2 months,the laboratory test revealed PLT 48 × 109/L,APTT 38.0 s and fibrinogen 0.53 g/L; Case 2:male 86 years old,he had skin petechia and ecchymosis,gingival bleeding for 2 weeks,the laboratory test revealed PLT 17 × 109/L,APTT 37.5 s and fibrinogen 0.51 g/L.CT scan for both cases revealed aortic aneurysm.They were diagnosed as aortic aneurysm associated chronic DIC.Both of them received blood component transfusion.After the treatment,they showed improvement in bleeding symtoms and laboratory data.They gave up operation,and were discharged from the hospital at last.Conclusions Blood replacement can alleviate bleeding tendency in those patients with chronic DIC associated with aortic dissecting aneurysm.