中华眼底病杂志
中華眼底病雜誌
중화안저병잡지
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
2013年
1期
9-12
,共4页
糖尿病视网膜病变/并发症%黄斑水肿%体层摄影术,光学相干
糖尿病視網膜病變/併髮癥%黃斑水腫%體層攝影術,光學相榦
당뇨병시망막병변/병발증%황반수종%체층섭영술,광학상간
Diabetic retinopathy/complications%Macular edema%Tomography,optical coherence
目的 观察糖尿病黄斑水肿(DME)患者中心凹下脉络膜厚度(SFCT)的变化.方法 横断面观察研究.20例DME患者32只眼纳入研究.男性12例,女性8例.平均年龄(57.6±9.3)岁.均行最佳矫正视力(BCVA)、频域(SD)光相干断层扫描(OCT)、验光检查.根据OCT黄斑水肿形态,分为弥漫水肿型、囊样水肿型、浆液性神经上皮脱离型、硬性渗出为主型.应用Cirrus HD-OCT对患眼黄斑区行加强深度扫描(EDI),测量SFCT.与国内同年龄段正常人群平均SFCT值(286.84±28.80) μm进行比较.患者年龄、屈光度、糖尿病病程、空腹血糖、BCVA、中央视网膜厚度与SFCT的相关性应用Pearson相关分析；不同类型黄斑水肿间SFCT差异比较行单因素变量分析.结果 患眼SFCT 120.50～361.50μm,平均SFCT(223.81±43.74) μm,与正常人群平均SFCT值比较,厚度下降63.03 μm,差异有统计学意义(95％可信区间-78.80～-47.26 μm,P＜0.01)；相关性分析结果显示,SFCT与患者年龄(r=0.124)、屈光度(r=0.277)、糖尿病病程(r=0.286)、空腹血糖水平(r=0.408)、BCVA(r=0.087)、中央视网膜厚度(r=0.036)无相关性(P＞0.05)；不同类型黄斑水肿之间SFCT值比较,差异无统计学意义(F=0.042,P＞0.05).结论 DME患者SFCT较同年龄段正常人群明显变薄.
目的 觀察糖尿病黃斑水腫(DME)患者中心凹下脈絡膜厚度(SFCT)的變化.方法 橫斷麵觀察研究.20例DME患者32隻眼納入研究.男性12例,女性8例.平均年齡(57.6±9.3)歲.均行最佳矯正視力(BCVA)、頻域(SD)光相榦斷層掃描(OCT)、驗光檢查.根據OCT黃斑水腫形態,分為瀰漫水腫型、囊樣水腫型、漿液性神經上皮脫離型、硬性滲齣為主型.應用Cirrus HD-OCT對患眼黃斑區行加彊深度掃描(EDI),測量SFCT.與國內同年齡段正常人群平均SFCT值(286.84±28.80) μm進行比較.患者年齡、屈光度、糖尿病病程、空腹血糖、BCVA、中央視網膜厚度與SFCT的相關性應用Pearson相關分析；不同類型黃斑水腫間SFCT差異比較行單因素變量分析.結果 患眼SFCT 120.50～361.50μm,平均SFCT(223.81±43.74) μm,與正常人群平均SFCT值比較,厚度下降63.03 μm,差異有統計學意義(95％可信區間-78.80～-47.26 μm,P＜0.01)；相關性分析結果顯示,SFCT與患者年齡(r=0.124)、屈光度(r=0.277)、糖尿病病程(r=0.286)、空腹血糖水平(r=0.408)、BCVA(r=0.087)、中央視網膜厚度(r=0.036)無相關性(P＞0.05)；不同類型黃斑水腫之間SFCT值比較,差異無統計學意義(F=0.042,P＞0.05).結論 DME患者SFCT較同年齡段正常人群明顯變薄.
목적 관찰당뇨병황반수종(DME)환자중심요하맥락막후도(SFCT)적변화.방법 횡단면관찰연구.20례DME환자32지안납입연구.남성12례,녀성8례.평균년령(57.6±9.3)세.균행최가교정시력(BCVA)、빈역(SD)광상간단층소묘(OCT)、험광검사.근거OCT황반수종형태,분위미만수종형、낭양수종형、장액성신경상피탈리형、경성삼출위주형.응용Cirrus HD-OCT대환안황반구행가강심도소묘(EDI),측량SFCT.여국내동년령단정상인군평균SFCT치(286.84±28.80) μm진행비교.환자년령、굴광도、당뇨병병정、공복혈당、BCVA、중앙시망막후도여SFCT적상관성응용Pearson상관분석；불동류형황반수종간SFCT차이비교행단인소변량분석.결과 환안SFCT 120.50～361.50μm,평균SFCT(223.81±43.74) μm,여정상인군평균SFCT치비교,후도하강63.03 μm,차이유통계학의의(95％가신구간-78.80～-47.26 μm,P＜0.01)；상관성분석결과현시,SFCT여환자년령(r=0.124)、굴광도(r=0.277)、당뇨병병정(r=0.286)、공복혈당수평(r=0.408)、BCVA(r=0.087)、중앙시망막후도(r=0.036)무상관성(P＞0.05)；불동류형황반수종지간SFCT치비교,차이무통계학의의(F=0.042,P＞0.05).결론 DME환자SFCT교동년령단정상인군명현변박.
Objective To observe the subfoveal choroidal thickness (SFCT) in eyes of patients with diabetic macular edema (DME).Methods Twenty patients (32 eyes) with DME were enrolled in this crosssectional observational study.The patients included 12 males and eight females,with a mean age of (47.3± 10.2) years.All the patients were examined documenting best corrected visual acuity (BCVA),spectraldomain optical coherence tomography (OCT) and ophthalmological examination.According to OCT DME morphology,samples are divided into diffuse macular edema,cystoid macular edema,serous retinal detachment and hard exudate groups.The SFCT was measured by a Cirrus HD-OCT with enhanced depth imaging (EDI) and was compared with the average SFCT (286.84 ± 28.80) μm of same age group.Correlation between SFCT and age,diopter,diabetic duration,fasting blood glucose,BCVA and central retinal thickness were analyzed by Pearson Analysis.SFCT of different DME types were analyzed by ANOVA Analysis.Results The mean SFCT of 32 eyes was (223.81±43.74) μm (ranging from 120.50 to 361.50 μm),which was lower by 63.03 μm (95％ confidence interval,-78.80 to-47.26 μm,P＜0.01)from normal SFCT.SFCT was independent of age (r=0.124),diopter (r=0.277),diabetic duration (r=0.286),fasting blood glucose (r=0.408),BCVA (r=0.087),and central retinal thickness (r=0.036).There was no significant difference of SFCT between different DME types (F =0.042,P ＞ 0.05).Conclusion SFCT is thinner in eyes with DME as compared to normal eyes of the same age.
