CAJ | 학술논문

目的比较3种不同图像模式测量的脉络膜厚度值差异.方法临床检查确诊的中心性浆液性脉络膜视网膜病变患者20例21只眼(A组)纳入研究.所有患眼视网膜倾斜且与水平线夹角大于5.0°.选取视网膜倾斜角度测量结果为视网膜水平的20例21只眼(B组)作为对照.2组间性别、年龄、等效球镜度数等比较,差异均无统计学意义(t=0.00、-0.345、0.489,P＞0.05).频域光相干断层扫描增强扫描模式下分别在1∶1像素、1∶1 ∶m、连续测量3种图像模式下测量其距离黄斑中心凹鼻侧或者颞侧1500∶m处的脉络膜厚度.比较1∶1像素模式、连续测量模式与1∶1 μm模式测量的脉络膜厚度值的差异.结果 A组1∶1μm、1∶1像素、连续测量图像模式测量所得脉络膜厚度分别为(304.81±87.74)、(342.86±91.43)、(307.86±89.35) μm.1∶1像素图像模式测得的脉络膜厚度值比1∶1 μm图像模式测得的脉络膜厚度值显著增加,差异有统计学意义(t=-8.499,P＜0.01)；连续测量图像模式测得的脉络膜厚度值与1∶1 μm图像模式测得的脉络膜厚度值比较,差异无统计学意义(t=-0.790,P＞0.05).B组1∶1像素图像模式、连续测量图像模式脉络膜厚度测量值与1∶1 μm图像模式脉络膜厚度测量值比较,差异均无统计学意义(t=-1.521、-1.822,P＞0.05).结论 1∶1像素图像模式测量的脉络膜厚度值偏大；1∶1μm图像模式测量脉络膜厚度较为准确；连续测量图像模式提供了随访测量脉络膜厚度更方便准确的方法.
목적 비교3충불동도상모식측량적맥락막후도치차이.방법 림상검사학진적중심성장액성맥락막시망막병변환자20례21지안(A조)납입연구.소유환안시망막경사차여수평선협각대우5.0°.선취시망막경사각도측량결과위시망막수평적20례21지안(B조)작위대조.2조간성별、년령、등효구경도수등비교,차이균무통계학의의(t=0.00、-0.345、0.489,P＞0.05).빈역광상간단층소묘증강소묘모식하분별재1∶1상소、1∶1 ∶m、련속측량3충도상모식하측량기거리황반중심요비측혹자섭측1500∶m처적맥락막후도.비교1∶1상소모식、련속측량모식여1∶1 μm모식측량적맥락막후도치적차이.결과 A조1∶1μm、1∶1상소、련속측량도상모식측량소득맥락막후도분별위(304.81±87.74)、(342.86±91.43)、(307.86±89.35) μm.1∶1상소도상모식측득적맥락막후도치비1∶1 μm도상모식측득적맥락막후도치현저증가,차이유통계학의의(t=-8.499,P＜0.01)；련속측량도상모식측득적맥락막후도치여1∶1 μm도상모식측득적맥락막후도치비교,차이무통계학의의(t=-0.790,P＞0.05).B조1∶1상소도상모식、련속측량도상모식맥락막후도측량치여1∶1 μm도상모식맥락막후도측량치비교,차이균무통계학의의(t=-1.521、-1.822,P＞0.05).결론 1∶1상소도상모식측량적맥락막후도치편대；1∶1μm도상모식측량맥락막후도교위준학；련속측량도상모식제공료수방측량맥락막후도경방편준학적방법.
Objective To compare the differences in the choroidal thickness at 1500 μm nasal or temporal to the fovea between three measurements of different imaging modes.Methods In this retrospective study,21 eyes from 20 patients diagnosed with central serous chorioretinopathy (CSC),whose retinas tilt over 5.0 degree to the horizontal line were included (retina tilt group).The control group (retinal horizontal group) also included 21 eyes from 20 individuals whose retinas are horizontal indicated by retinal tilt angle measurement.There were no statistical significance (t=0.00,-0.345,0.489; P＞0.05) in gender,age and spherical equivalent distributions between the two groups.The choroidal thickness at 1500μm nasal or temporal to the fovea was measured by spectral-domain optical coherence tomography (COT) enhanced depth scanning under three modes (1∶1 pixel,1∶1 micron and continuous measurement).The differences of choroidal thickness between these three measure modes were analyzed by a paired t test.Results The choroidal thickness was (304.81± 87.74),(342.86± 91.43),(307.86± 89.35) μm respectively measured by 1 ∶ 1 pixel,1 ∶ 1 micron and continuous measurement modes in retinal tilt group.The choroidal thickness measured by 1 ∶ 1 pixel was increased compare to that by 1 ∶ 1 micron,the difference was statistically significant (t =-8.499,P ＜ 0.01).The choroidal thickness measured by continuous measurement mode was the same of that by 1∶1 micron,the difference was not statistically significant (t=0.790,P＞0.05).In retinal horizontal group,the choroidal thickness measured by these 3 modes was the same,the difference was not statistically significant (t =-1.521,-1.822; P ＞ 0.05).Conclusions Spectralis OCT with 1∶1 pixel mode exhibits horizontally compressed image,the values of choroidal thickness under tilted retinas measured by this condition were significantly greater than the true ones.The choroidal thickness measured by 1∶1 micron mode measurement is more accurate.Continuous measurement mode provides more accurate and convenient choroidal thickness measurement during follow up of patients.