CAJ | 학술논문

目的评估自体唇腺移植治疗重症干眼的短期临床疗效.方法对8例(8只眼)重症干眼患者进行了自体唇腺移植,术后随访6个月,并对患者的术前、术后临床资料,包括最佳矫正视力、泪液分泌试验、主观满意度、主观症状评分、人工泪液使用、泪液镜以及裂隙灯显微镜检查等进行评估.结果所有移植腺体术后存活率100％.患者术前及术后1周及1、3、6个月眼干、异物感、畏光、烧灼感等评分均值分别为11.17、5.67、4.33、4.25,人工泪液使用频率分别为16、9、4、3、3次/d.但患者术后的最佳矫正视力、泪液镜检查评分无明显提高.结论自体唇腺移植是治疗重症干眼行之有效的方法,但其长期疗效尚需进一步研究.
목적 평고자체진선이식치료중증간안적단기림상료효.방법 대8례(8지안)중증간안환자진행료자체진선이식,술후수방6개월,병대환자적술전、술후림상자료,포괄최가교정시력、루액분비시험、주관만의도、주관증상평분、인공루액사용、루액경이급렬극등현미경검사등진행평고.결과 소유이식선체술후존활솔100％.환자술전급술후1주급1、3、6개월안간、이물감、외광、소작감등평분균치분별위11.17、5.67、4.33、4.25,인공루액사용빈솔분별위16、9、4、3、3차/d.단환자술후적최가교정시력、루액경검사평분무명현제고.결론 자체진선이식시치료중증간안행지유효적방법,단기장기료효상수진일보연구.
Objective Aotologous labial salivary gland transplantation has been a promising alternative for the treatment of severe dry eye.In this article,we describe the results of the ocular surface changes after labial salivary gland transplantation and investigate the feasiblity of this treatment.Methods The results of this technique in 8 patients (eyes) who suffered from severe dry eye were prospectively analyzed after surgery (follow-up of 6 months).The best-corrected visual acuity,Schirmer Ⅰ test,degree of discomfort,usage of pharmaceutical tear substitutes,tear interferometry and slit lamp examination were investigated at different time before and after surgery.Results All grafts remained viable and the survival rate is 100％.All patients showed significant increase in the Schirmer's test and they expressed great improvement in their ocular discomfort.The use of artificial tear substitutes was reduced because of the increased ocular surface lubrication.Conclusion Although the authors' long-term experience still is limited,we believe that the procedure is a promising alternative approach for severe dry eye