中华眼科杂志
中華眼科雜誌
중화안과잡지
Chinese Journal of Ophthalmology
2013年
1期
37-40
,共4页
儿童%眼肿瘤%视网膜母细胞瘤%皮样囊肿
兒童%眼腫瘤%視網膜母細胞瘤%皮樣囊腫
인동%안종류%시망막모세포류%피양낭종
Child%Eye neoplasms%Retinoblastoma%Dermoid cyst
目的 探讨儿童眼部肿瘤的病理分类特点.方法 回顾性系列病例研究.对2001年1月至2007年12月河南省眼科研究所病理室存档的213例214只眼儿童眼部肿瘤的病理诊断按发病部位及性质进行分类.患儿年龄2个月至14岁,男性123例123只眼,女性90例91只眼.结果 眼睑肿瘤17例17只眼(7.94％),均为良性肿瘤,位居前两位的是囊肿和鳞状上皮乳头状瘤,前者4例4只眼,包括表皮样囊肿1例1只眼和皮样囊肿3例3只眼,后者3例3只眼；结膜和角膜肿瘤84例84只眼(39.25％),其中恶性肿瘤1例(1.19％),为上皮内瘤变,其余均为良性肿瘤,前3位依次为角膜皮样瘤64例(76.19％),结膜色素痣10例(11.49％),鳞状上皮乳头状瘤4例(4.76％)；眼内肿瘤73例73只眼(34.11％),包括视网膜母细胞瘤66例66只眼(90.41％),葡萄膜肿瘤7例7只眼(9.59％),其中虹膜囊肿6例,虹膜黑色素瘤1例；37例38只眼(17.76％)眼眶肿瘤中,良性肿瘤32例33只眼,其中前3位依次是囊肿16例16只眼(42.11％),血管错构瘤7例7只眼(18.42％),炎性假瘤3例4只眼(10.53％),恶性肿瘤5例5只眼,其中继发性肿瘤3例3只眼(7.89％),均为视网膜母细胞瘤眶内蔓延,横纹肌肉瘤2例2只眼(5.26％)；巩膜肿瘤2例2只眼(0.93％),巩膜骨性迷芽瘤及先天性巩膜囊肿各1例.良性肿瘤共134例135只眼(63.08％),恶性肿瘤共79例79只眼(36.92％).结论 儿童眼部肿瘤以胚胎性和先天性肿瘤为主,视网膜母细胞瘤是儿童最常见的眼部肿瘤,其次是角膜皮样瘤.
目的 探討兒童眼部腫瘤的病理分類特點.方法 迴顧性繫列病例研究.對2001年1月至2007年12月河南省眼科研究所病理室存檔的213例214隻眼兒童眼部腫瘤的病理診斷按髮病部位及性質進行分類.患兒年齡2箇月至14歲,男性123例123隻眼,女性90例91隻眼.結果 眼瞼腫瘤17例17隻眼(7.94％),均為良性腫瘤,位居前兩位的是囊腫和鱗狀上皮乳頭狀瘤,前者4例4隻眼,包括錶皮樣囊腫1例1隻眼和皮樣囊腫3例3隻眼,後者3例3隻眼；結膜和角膜腫瘤84例84隻眼(39.25％),其中噁性腫瘤1例(1.19％),為上皮內瘤變,其餘均為良性腫瘤,前3位依次為角膜皮樣瘤64例(76.19％),結膜色素痣10例(11.49％),鱗狀上皮乳頭狀瘤4例(4.76％)；眼內腫瘤73例73隻眼(34.11％),包括視網膜母細胞瘤66例66隻眼(90.41％),葡萄膜腫瘤7例7隻眼(9.59％),其中虹膜囊腫6例,虹膜黑色素瘤1例；37例38隻眼(17.76％)眼眶腫瘤中,良性腫瘤32例33隻眼,其中前3位依次是囊腫16例16隻眼(42.11％),血管錯構瘤7例7隻眼(18.42％),炎性假瘤3例4隻眼(10.53％),噁性腫瘤5例5隻眼,其中繼髮性腫瘤3例3隻眼(7.89％),均為視網膜母細胞瘤眶內蔓延,橫紋肌肉瘤2例2隻眼(5.26％)；鞏膜腫瘤2例2隻眼(0.93％),鞏膜骨性迷芽瘤及先天性鞏膜囊腫各1例.良性腫瘤共134例135隻眼(63.08％),噁性腫瘤共79例79隻眼(36.92％).結論 兒童眼部腫瘤以胚胎性和先天性腫瘤為主,視網膜母細胞瘤是兒童最常見的眼部腫瘤,其次是角膜皮樣瘤.
목적 탐토인동안부종류적병리분류특점.방법 회고성계렬병례연구.대2001년1월지2007년12월하남성안과연구소병리실존당적213례214지안인동안부종류적병리진단안발병부위급성질진행분류.환인년령2개월지14세,남성123례123지안,녀성90례91지안.결과 안검종류17례17지안(7.94％),균위량성종류,위거전량위적시낭종화린상상피유두상류,전자4례4지안,포괄표피양낭종1례1지안화피양낭종3례3지안,후자3례3지안；결막화각막종류84례84지안(39.25％),기중악성종류1례(1.19％),위상피내류변,기여균위량성종류,전3위의차위각막피양류64례(76.19％),결막색소지10례(11.49％),린상상피유두상류4례(4.76％)；안내종류73례73지안(34.11％),포괄시망막모세포류66례66지안(90.41％),포도막종류7례7지안(9.59％),기중홍막낭종6례,홍막흑색소류1례；37례38지안(17.76％)안광종류중,량성종류32례33지안,기중전3위의차시낭종16례16지안(42.11％),혈관착구류7례7지안(18.42％),염성가류3례4지안(10.53％),악성종류5례5지안,기중계발성종류3례3지안(7.89％),균위시망막모세포류광내만연,횡문기육류2례2지안(5.26％)；공막종류2례2지안(0.93％),공막골성미아류급선천성공막낭종각1례.량성종류공134례135지안(63.08％),악성종류공79례79지안(36.92％).결론 인동안부종류이배태성화선천성종류위주,시망막모세포류시인동최상견적안부종류,기차시각막피양류.
Objective To analyze the pathological classification of ocular tumor in children.Methods 213 cases (214 eyes) of ocular tumor in children below 14 years old between January 2001 and December 2007 in Henan Eye Institute were reviewed retrospectively,the pathological classification were made according to the location and nature of the tumor.Results There were 17 eyes (7.94％) of 214 eyes with benign tumor of eyelid,the leading two tumor were 4 eyes with cyst,in which 1 eye with epidermoid cyst and 3 eyes with dermoid cyst were included,and 3 eyes with squamous papilloma.There were 84 eyes (39.25％) of 214 eyes with conjunctival and corneal tumor,1 eye with intraepithelial tumor was found,other tumors were all benign tumor,the leading three tumors were corneal dermoid (64 eyes),conjunctival nevus (10 eyes) and suamous papilloma (4 eyes).There were 73 eyes (34.11％) with intraocular tumor including 66 eyes (90.41％) with retinoblastoma,6 eyes (8.22％) with iris cyst and 1 eye (1.37％) with iris melanoma.Of 38 eyes of orbital tumor,cyst (16 eyes),vascular hamartoma (7 eyes) and inflammatory pseudotumor (4 eyes) were the most common benign tumors,there were 3 eyes (7.89％) with orbital extention of retinoblastoma and 2 eyes (5.26％) with rhabdosarcoma.There were 2 eyes with scleral tumor,including 1 eye with scleral bony choristoma and 1 eye with congenital scleral cyst.Altogether,there are 135 eyes (63.08％) with benign tumor and 79 eyes (36.92％) with malignant tumors.Conclusions Most children's ocular tumors are congenital and embryonic tumors.Retinoblastoma is the most common malignant ocular tumor in children,then is corneal dermoid.
