中华眼科杂志
中華眼科雜誌
중화안과잡지
Chinese Journal of Ophthalmology
2013年
7期
615-620
,共6页
龚静文%孙朝晖%王丽萍%申屠形超%宋峰伟
龔靜文%孫朝暉%王麗萍%申屠形超%宋峰偉
공정문%손조휘%왕려평%신도형초%송봉위
弱视%视敏度%对比敏感度%深度知觉
弱視%視敏度%對比敏感度%深度知覺
약시%시민도%대비민감도%심도지각
Amblyopia%Visual acuity%Contrast sensitivity%Depth perception
目的 探讨斜视性和屈光参差性弱视存在的视功能缺损模式.方法 病例对照研究.运用光栅视敏度、边缘对比敏感度、双眼融合、对比敏感度函数等视功能检测方法,对147例8～40岁的弱视患者,进行视功能检测.对弱视患者的视敏度与光栅视敏度函数(CSF)、边缘对比敏感度分别进行相关性及回归分析；对斜视性和屈光参差性弱视患者在各个空间频率下的对比敏感度进行成组设计的两样本均数t检验；对有双眼视功能组与无双眼视功能组的视敏度进行两样本均数t检验.结果 正常对照眼其光栅视敏度为1.82′±0.25′,边缘对比敏感度为0.019±0.007.视敏度与光栅视敏度之间呈强相关性(R=0.81)；最佳拟合直线斜率为0.55,视敏度与边缘对比敏感度之间呈弱相关性(R=0.24).斜视性弱视样本的散点图分布约低于总体趋势的15％；总体弱视样本的边缘对比敏感度与视觉敏锐度的呈弱相关性(R=0.24).屈光参差性样本的对比敏感度阈值的分布约高于(差于)总体趋势的15％,斜视及混合性弱视样本的对比敏感度阈值分布约低于(好于)总体趋势的17％.屈光参差性弱视眼和斜视性弱视眼CSF曲线均较相对健眼的CSF低平,峰值向低空间频率区移位,在中高空间频率区有明显受损,在1.0 c/d的低频区分别为0.053±0.060和0.025±0.011,两者差异有统计学意义(t=2.239,P＜0.05).结论 斜视性和屈光参差性弱视视敏度、光栅视敏度、边缘对比敏感度、CSF存在不同程度的缺损,两者在视功能方面也有一些特征性改变.
目的 探討斜視性和屈光參差性弱視存在的視功能缺損模式.方法 病例對照研究.運用光柵視敏度、邊緣對比敏感度、雙眼融閤、對比敏感度函數等視功能檢測方法,對147例8～40歲的弱視患者,進行視功能檢測.對弱視患者的視敏度與光柵視敏度函數(CSF)、邊緣對比敏感度分彆進行相關性及迴歸分析；對斜視性和屈光參差性弱視患者在各箇空間頻率下的對比敏感度進行成組設計的兩樣本均數t檢驗；對有雙眼視功能組與無雙眼視功能組的視敏度進行兩樣本均數t檢驗.結果 正常對照眼其光柵視敏度為1.82′±0.25′,邊緣對比敏感度為0.019±0.007.視敏度與光柵視敏度之間呈彊相關性(R=0.81)；最佳擬閤直線斜率為0.55,視敏度與邊緣對比敏感度之間呈弱相關性(R=0.24).斜視性弱視樣本的散點圖分佈約低于總體趨勢的15％；總體弱視樣本的邊緣對比敏感度與視覺敏銳度的呈弱相關性(R=0.24).屈光參差性樣本的對比敏感度閾值的分佈約高于(差于)總體趨勢的15％,斜視及混閤性弱視樣本的對比敏感度閾值分佈約低于(好于)總體趨勢的17％.屈光參差性弱視眼和斜視性弱視眼CSF麯線均較相對健眼的CSF低平,峰值嚮低空間頻率區移位,在中高空間頻率區有明顯受損,在1.0 c/d的低頻區分彆為0.053±0.060和0.025±0.011,兩者差異有統計學意義(t=2.239,P＜0.05).結論 斜視性和屈光參差性弱視視敏度、光柵視敏度、邊緣對比敏感度、CSF存在不同程度的缺損,兩者在視功能方麵也有一些特徵性改變.
목적 탐토사시성화굴광삼차성약시존재적시공능결손모식.방법 병례대조연구.운용광책시민도、변연대비민감도、쌍안융합、대비민감도함수등시공능검측방법,대147례8～40세적약시환자,진행시공능검측.대약시환자적시민도여광책시민도함수(CSF)、변연대비민감도분별진행상관성급회귀분석；대사시성화굴광삼차성약시환자재각개공간빈솔하적대비민감도진행성조설계적량양본균수t검험；대유쌍안시공능조여무쌍안시공능조적시민도진행량양본균수t검험.결과 정상대조안기광책시민도위1.82′±0.25′,변연대비민감도위0.019±0.007.시민도여광책시민도지간정강상관성(R=0.81)；최가의합직선사솔위0.55,시민도여변연대비민감도지간정약상관성(R=0.24).사시성약시양본적산점도분포약저우총체추세적15％；총체약시양본적변연대비민감도여시각민예도적정약상관성(R=0.24).굴광삼차성양본적대비민감도역치적분포약고우(차우)총체추세적15％,사시급혼합성약시양본적대비민감도역치분포약저우(호우)총체추세적17％.굴광삼차성약시안화사시성약시안CSF곡선균교상대건안적CSF저평,봉치향저공간빈솔구이위,재중고공간빈솔구유명현수손,재1.0 c/d적저빈구분별위0.053±0.060화0.025±0.011,량자차이유통계학의의(t=2.239,P＜0.05).결론 사시성화굴광삼차성약시시민도、광책시민도、변연대비민감도、CSF존재불동정도적결손,량자재시공능방면야유일사특정성개변.
Objective To elucidate the difference in the pathogenesis between strabismic and anisometropic amblyopia.Methods It was a case-control study.We used psychophysical methods,including grating acuity,edge contrast sensitivity,contrast sensitivity function tests,and examined the visual functions of 150 cases from 8 to 40-year-old.Then we applied the Origin 8.0 software for statistical analysis of experimental data,we did the correlation analysis between the grating acuity,edge contrast sensitivity and optotype acuity,and the similarity comparison of the contrast sensitivity function curve between the strabismic and anisometropic amblyopia.Results The grating acuity had a strong correlation with optotype acuity,the correlation value was 0.81.The grating acuity of the srabismic group was roughly 15％ lower than the whole abnormal population,for any given level of optotype acuity;the edge contrast threshold had a weak correlation with optotype acuity,the correlation value was 0.24.Anisometropes,for a given level of optotype acuity,had edge contrast thresholds that were 15％ higher(worse)than the whole population,while strabismic and strabismic-anisometropes had edge contrast thresholds that are 17％ lower(better)than the whole population.The CSF of all amblyopic eyes were reduced in comparison with the non-amblyopic eye of the same person,the peak sensitivity shifted toward to the low spatial frequency region,the CS curve was depressed especially in the middle and high spatial frequencies,there were no significant difference,but at low frequency area(1.0 c/d)there were statistically significant between the two types of amblyopia(t=2.239,P＜0.05).Conclusion There were differences in the patterns of visual loss between strabismic and anisometropic amblyopic patients.
