CAJ | 학술논문

感染性角膜炎是一种严重的致盲性眼病,早期病原学诊断直接影响着患者的治疗效果.如何快速、准确地鉴别致病病原体目前还是一个挑战.活体共聚焦显微镜检查(IVCM)作为一种非侵入性图像诊断技术,可在细胞水平提供高分辨率图像以显示眼表组织的结构特征.IVCM对感染性角膜炎中棘阿米巴性角膜炎及丝状真菌性角膜炎的诊断具有重要应用价值,已在临床开始推广使用,逐渐成为感染角膜炎随诊的客观依据.本文对近年来IVCM在感染性角膜炎诊治中的应用及进展进行综述.
감염성각막염시일충엄중적치맹성안병,조기병원학진단직접영향착환자적치료효과.여하쾌속、준학지감별치병병원체목전환시일개도전.활체공취초현미경검사(IVCM)작위일충비침입성도상진단기술,가재세포수평제공고분변솔도상이현시안표조직적결구특정.IVCM대감염성각막염중극아미파성각막염급사상진균성각막염적진단구유중요응용개치,이재림상개시추엄사용,축점성위감염각막염수진적객관의거.본문대근년래IVCM재감염성각막염진치중적응용급진전진행종술.
Infectious keratitis remains a severe ocular condition that can lead to irreversible conplications and even blindness.An early diagnosis of an infective microorganism leading to effective treatment may improve the outcome of infectious keratitis.However,the accurate and rapid identification of the infectious agent remains a challenge for the ophthalmologist.In vivo confocal microscopy (IVCM) is a noninvasive imaging technique that provides high-resolution images of ocular surface structures at a cellular level and infectious keratitis represents one of its most important clinical uses.The value of IVCM has been demonstrated in the diagnosis of acanthamoeba and filamentous fungal keratitis.The follow-up of such corneal infections may also be improved by this noninvasive imaging technique.However,the current resolution of IVCM limits its use in cases of bacterial and viral keratitis.