CAJ | 학술논문

目的探讨颈部血管彩色超声检查发现的劲动脉狭窄对视网膜分支静脉阻塞(BRVO)患者的临床意义.方法病例对照研究.以云南省大理州人民医院眼科2010年1月至2012年1月收治的BRVO患者30例为观察组,同期无眼部症状及全身不适症状的30名健康体检者为对照组,对两组患者进行颈部血管彩色超声检查.应用x2检验对颈动脉粥样斑块发生率和颈动脉狭窄率及颈动脉阻力指数(resistance index,RI)进行比较,并对颈动脉狭窄率及颈动脉RI进行Logistic回归分析.结果观察组30例BRVO患者中,有颈动脉粥样斑块23例,发生率为76.7％,有颈动脉狭窄19例,发生率为63.3％,平均RI为0.66;对照组中有颈动脉粥样斑块6例,发生率为20.0％,有颈动脉狭窄3例,发生率为10.0％,平均RI为0.61;观察组患者的颈动脉粥样斑块发生率、颈动脉狭窄发生率及平均RI明显高于对照组,差异有统计学意义(P值均＜0.05).Logistic回归分析结果显示,颈动脉狭窄(偏回归系数为2.263,OR =9.611,P=0.004)与RI(偏回归系数为23.713,OR=669.273,P=0.006)对BRVO的患病有影响,是BRVO患病的危险因素.结论颈动脉血管彩色超声检查发现的早期颈动脉粥样硬化和颈动脉血管狭窄情况对预防或治疗BRVO疾病具有重要的意义.
목적 탐토경부혈관채색초성검사발현적경동맥협착대시망막분지정맥조새(BRVO)환자적림상의의.방법 병례대조연구.이운남성대리주인민의원안과2010년1월지2012년1월수치적BRVO환자30례위관찰조,동기무안부증상급전신불괄증상적30명건강체검자위대조조,대량조환자진행경부혈관채색초성검사.응용x2검험대경동맥죽양반괴발생솔화경동맥협착솔급경동맥조력지수(resistance index,RI)진행비교,병대경동맥협착솔급경동맥RI진행Logistic회귀분석.결과 관찰조30례BRVO환자중,유경동맥죽양반괴23례,발생솔위76.7％,유경동맥협착19례,발생솔위63.3％,평균RI위0.66;대조조중유경동맥죽양반괴6례,발생솔위20.0％,유경동맥협착3례,발생솔위10.0％,평균RI위0.61;관찰조환자적경동맥죽양반괴발생솔、경동맥협착발생솔급평균RI명현고우대조조,차이유통계학의의(P치균＜0.05).Logistic회귀분석결과현시,경동맥협착(편회귀계수위2.263,OR =9.611,P=0.004)여RI(편회귀계수위23.713,OR=669.273,P=0.006)대BRVO적환병유영향,시BRVO환병적위험인소.결론 경동맥혈관채색초성검사발현적조기경동맥죽양경화화경동맥혈관협착정황대예방혹치료BRVO질병구유중요적의의.
Objective To discuss the clinical significance of the neck vascular ultrasound examination in patients with branch retinal vein occlusion (BRVO).Methods Case-control study.Thirty patients of BRVO and 30 healthy subjects with no ophthalmic and systemic symptoms were recruited from January 2010 to January 2012 in the Department of Ophthalmology of the First People's Hospital of Dali Prefecture.The neck vascular ultrasound examination was performed in two groups.The incidence of carotid atheromatous plaque,the rate of carotid stenosis and the carotid artery resistance index (RI) were compared using chi square test.Logistic regression analysis of the rate of carotid stenosis and carotid artery RI were performed.Results In BRVO group,23 cases had carotid atheromatous plaque with the incidence of 76.7％ Nineteen cases had carotid stenosis with the incidence of 63.3％.The average carotid artery RI was 0.66.In control group,carotid artery atheromatous plaque was found on 6 subjects with incidence of 20.0％.Carotid artery stenosis was detected in 3 subjects with incidence of 10.0％.The average carotid artery RI was 0.61.The incidence of carotid artery atheromatous plaque and carotid stenosis and carotid artery RI in BRVO group were significantly higher than the control group.The difference was statistically significant(P ＜ 0.05).Logistic regression analysis showed that carotid artery stenosis(partial regression coefficient =2.263,OR =9.611,P =0.004) and carotid artery RI (partial regression coefficient =23.713,OR =669.273,P =0.006) had influence in BRVO patients as risk factors.Conclusion Early detection of carotid scleratheroma and carotid artery stenosis by the carotid artery ultrasound examination played an important role in prevention or treatment of BRVO.