CAJ | 학술논문

目的探讨执行控制过程中健康人大脑前扣带回(ACC)与背外侧额前皮质(DLPFC)之间的功能连接及其与行为学表现之间的关系.方法 2011年1至5月25名17～20岁的健康志愿者在青岛大学医学院附属医院放射科进行3.0T功能磁共振扫描,采用注意网络测试(ANT)作为试验范式,计算ACC和DLPFC之间的功能连接,并与ANT的行为学得分做相关分析.结果在执行控制过程中,背侧ACC(dACC)与两侧的DLPFC之间存在显著的功能连接,其中左侧的dACC和DLPFC之间的功能连接系数与执行控制的行为学得分存在显著负相关(r=-0.63;P ＜0.01).结论 ACC与DLPFC之间存在功能连接,并对注意的执行控制功能存在有利的影响,这有助于我们理解注意功能中相关脑区的功能整合作用.
목적 탐토집행공제과정중건강인대뇌전구대회(ACC)여배외측액전피질(DLPFC)지간적공능련접급기여행위학표현지간적관계.방법 2011년1지5월25명17～20세적건강지원자재청도대학의학원부속의원방사과진행3.0T공능자공진소묘,채용주의망락측시(ANT)작위시험범식,계산ACC화DLPFC지간적공능련접,병여ANT적행위학득분주상관분석.결과 재집행공제과정중,배측ACC(dACC)여량측적DLPFC지간존재현저적공능련접,기중좌측적dACC화DLPFC지간적공능련접계수여집행공제적행위학득분존재현저부상관(r=-0.63;P ＜0.01).결론 ACC여DLPFC지간존재공능련접,병대주의적집행공제공능존재유리적영향,저유조우아문리해주의공능중상관뇌구적공능정합작용.
Objective To explore the presence of functional connectivity between anterior cingulate cortex (ACC) and dorsolateral prefrontal cortex (DLPFC) during the manipulation of attentional network test (ANT) and its relationship with behavioral performance.Methods Functional magnetic resonance imaging was performed on 25 healthy subjects aged 17-20 years.And ANT was used as a paradigm.Functional connectivity between ACC-DLPFC was tested and correlation analysis conducted between functional connectivity coefficients and behavioral scores of ANT.Results Significant functional connectivity between the dorsal ACC (dACC) with bilateral DLPFC was found.Furthermore,event-related functional connectivity coefficients between left dACC and lefi DLPFC were negatively associated with the behavioral scores of executive control (r =-0.63 ; P ＜ 0.01).Conclusion Our findings provide new evidence that ACC and DLPFC are functionally connected and such functional connectivity has advantageous influence on executive control function of attention so as to contribute to our understanding of the integrated role of these brain regions in attentional network.